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公开(公告)号：US20230414490A1
公开(公告)日：2023-12-28
申请号：US18244446
申请日：2023-09-11
申请人： Wyeth, LLC
IPC分类号： A61K9/00 , A61K47/18 , A61K31/485 , A61K47/02
CPC分类号： A61K9/0019 , A61K47/183 , A61K31/485 , A61K47/02
摘要： The present invention provides formulations that achieve effective delivery of methylnaltrexone compositions. The provided formulations are useful for preventing, treating delaying, diminishing or reducing the severity of side effects resulting from use of analgesic opioids.
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公开(公告)号：US09694078B2
公开(公告)日：2017-07-04
申请号：US15010116
申请日：2016-01-29
申请人： Wyeth LLC
发明人： Mahdi B. Fawzi , Tianmin Zhu , Syed M. Shah
摘要： The present invention relates to novel tigecycline compositions with improved stability in both solid and solution states and processes for making these compositions. These compositions comprise tigecycline, a suitable carbohydrate, and an acid or buffer.
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公开(公告)号：US09254328B2
公开(公告)日：2016-02-09
申请号：US14604924
申请日：2015-01-26
申请人： Wyeth LLC
发明人： Mahdi B. Fawzi , Tianmin Zhu , Syed M. Shah
摘要： The present invention relates to novel tigecycline compositions with improved stability in both solid and solution states and processes for making these compositions. These compositions comprise tigecycline, a suitable carbohydrate, and an acid or buffer.
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公开(公告)号：US10588975B2
公开(公告)日：2020-03-17
申请号：US15613588
申请日：2017-06-05
申请人： Wyeth LLC
发明人： Mahdi B. Fawzi , Tianmin Zhu , Syed M. Shah
摘要： The present invention relates to novel tigecycline compositions with improved stability in both solid and solution states and processes for making these compositions. These compositions comprise tigecycline, a suitable carbohydrate, and an acid or buffer.
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公开(公告)号：US20150141379A1
公开(公告)日：2015-05-21
申请号：US14604924
申请日：2015-01-26
申请人： Wyeth LLC
发明人： Mahdi B. Fawzi , Tianmin Zhu , Syed M. Shah
摘要： The present invention relates to novel tigecycline compositions with improved stability in both solid and solution states and processes for making these compositions. These compositions comprise tigecycline, a suitable carbohydrate, and an acid or buffer.
摘要翻译： 本发明涉及在固体和溶液状态下具有改善的稳定性的新型替加环素组合物以及制备这些组合物的方法。 这些组合物包含替加环素，合适的碳水化合物和酸或缓冲液。
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公开(公告)号：US20220023200A1
公开(公告)日：2022-01-27
申请号：US17357023
申请日：2021-06-24
申请人： Wyeth, LLC
IPC分类号： A61K9/00 , A61K47/18 , A61K31/485 , A61K47/02
摘要： The present invention provides formulations that achieve effective delivery of methylnaltrexone compositions. The provided formulations are useful for preventing, treating delaying, diminishing or reducing the severity of side effects resulting from use of analgesic opioids.
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公开(公告)号：US20200179270A1
公开(公告)日：2020-06-11
申请号：US16514722
申请日：2019-07-17
申请人： Wyeth, LLC
IPC分类号： A61K9/00 , A61K47/02 , A61K31/485 , A61K47/18
摘要： The present invention provides formulations that achieve effective delivery of methylnaltrexone compositions. The provided formulations are useful for preventing, treating delaying, diminishing or reducing the severity of side effects resulting from use of analgesic opioids.
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