公开(公告)号：US20240076279A1

公开(公告)日：2024-03-07

申请号：US18271523

申请日：2021-12-17

申请人： XUZHOU MEDICAL UNIVERSITY ,  SHANGHAITECH UNIVERSITY

发明人： Dong GUO ,  Xudong CAO ,  Wenzhong YAN ,  Jianjun CHENG ,  Ying SUN ,  Limin SU ,  Ying REN ,  Ruoqi WANG ,  Haoran ZHANG ,  Haoxing YUAN

IPC分类号： C07D401/12 ,  A61P13/12 ,  C07D223/16

CPC分类号： C07D401/12 ,  A61P13/12 ,  C07D223/16

摘要： The present application relates to a novel benzoazepine compound, comprising a pharmaceutically acceptable salt thereof. The present application also provides a pharmaceutical composition comprising the compound and a pharmaceutically acceptable salt thereof. The present application relates to use of the compound and the composition in the prevention or treatment of diseases related to arginine vasopressin V1a receptor, arginine vasopressin V1b receptor, arginine vasopressin V2 receptor, sympathetic nervous system or renin-angiotensin-aldosterone system. The present application also provides a method for preventing and/or treating arginine vasopressin-related diseases.