公开(公告)号：US20170095449A1

公开(公告)日：2017-04-06

申请号：US15290676

申请日：2016-10-11

Applicant: Xenon Pharmaceuticals Inc.

Inventor： Conrad Stewart Winters ,  Meidong Yang ,  Haigang Chen

IPC: A61K31/407 ,  A61K47/14 ,  A61K47/10 ,  A61K9/00 ,  A61K9/06

CPC classification number: A61K31/407 ,  A61K9/0014 ,  A61K9/06 ,  A61K47/10 ,  A61K47/14

Abstract: This invention is directed to pharmaceutical compositions for topical administration to a mammal, wherein the pharmaceutical compositions comprise a spiro-oxindole compound, as an enantiomer, a racemate or a non-racemic mixture, or a pharmaceutically acceptable salt thereof. These pharmaceutical compositions are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions.