公开(公告)号：US08753688B2

公开(公告)日：2014-06-17

申请号：US13260171

申请日：2009-12-10

申请人： Xijun Wang ,  Xiuhong Wu ,  Hui Sun ,  Wenjun Sun

发明人： Xijun Wang ,  Xiuhong Wu ,  Hui Sun ,  Wenjun Sun

IPC分类号： A61K9/00 ,  A61P31/14

CPC分类号： A61K9/00 ,  A61K9/0019 ,  A61K9/0095 ,  A61K9/02 ,  A61K9/06 ,  A61K9/12

摘要： A bear bile macromolecular extract with anti-HCV virus function is disclosed. A preparation method comprises the following steps of: taking fresh bear bile or dissolving bear bile powder with water, centrifuging it by a molecular sieve filter membrane with molecular weight cut-off of 100,000 or an ultrafiltration membrane, filtering to obtain sediment, dissolving the sediment with water, adding the solution to sephadex column, separating the solution by using water or buffer as elution solvent, and freeze-drying the eluent to obtain the bear bile macromolecular extract. Experiments show that the bear bile macromolecular extract has anti-HCV virus function and can be used for treating hepatitis C.

摘要翻译： 公开了具有抗HCV病毒功能的熊胆大分子提取物。 一种制备方法，包括：将新鲜的胆汁胆汁或溶解的胆汁粉末用水分离，用分子筛截止值为100,000的分子筛滤膜或超滤膜离心，过滤得到沉淀物，溶解沉淀物 用水加入到sephadex柱中，用水或缓冲液作为洗脱溶剂分离溶液，冷冻干燥洗脱液，得到熊胆大分子提取物。 实验表明，熊胆大分子提取物具有抗HCV病毒功能，可用于治疗丙型肝炎。

公开(公告)号：US20120020895A1

公开(公告)日：2012-01-26

申请号：US13260171

申请日：2009-12-10

申请人： Xijun Wang ,  Xiuhong Wu ,  Hui Sun ,  Wenjun Sun

发明人： Xijun Wang ,  Xiuhong Wu ,  Hui Sun ,  Wenjun Sun

IPC分类号： A61K35/413 ,  A61P31/14 ,  A61K9/12

CPC分类号： A61K9/00 ,  A61K9/0019 ,  A61K9/0095 ,  A61K9/02 ,  A61K9/06 ,  A61K9/12

摘要： A bear bile macromolecular extract with anti-HCV virus function is disclosed. A preparation method comprises the following steps of: taking fresh bear bile or dissolving bear bile powder with water, centrifuging it by a molecular sieve filter membrane with molecular weight cut-off of 100,000 or an ultrafiltration membrane, filtering to obtain sediment, dissolving the sediment with water, adding the solution to sephadex column, separating the solution by using water or buffer as elution solvent, and freeze-drying the eluent to obtain the bear bile macromolecular extract. Experiments show that the bear bile macromolecular extract has anti-HCV virus function and can be used for treating hepatitis C.

摘要翻译： 公开了具有抗HCV病毒功能的熊胆大分子提取物。 一种制备方法，包括：将新鲜的胆汁胆汁或溶解的胆汁粉末用水分离，用分子筛截止值为100,000的分子筛滤膜或超滤膜离心，过滤得到沉淀物，溶解沉淀物 用水加入到sephadex柱中，用水或缓冲液作为洗脱溶剂分离溶液，冷冻干燥洗脱液，得到熊胆大分子提取物。 实验表明，熊胆大分子提取物具有抗HCV病毒功能，可用于治疗丙型肝炎。