公开(公告)号：US20160069896A1

公开(公告)日：2016-03-10

申请号：US14652425

申请日：2013-12-16

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Irun R. COHEN ,  Eytan DOMANY ,  Ittai FATTAL ,  Noam SHENTAL

IPC: G01N33/68

CPC classification number: G01N33/6854 ,  G01N33/564 ,  G01N2800/104 ,  G01N2800/60

Abstract: Methods and kits for diagnosing systemic lupus erythematosus (SLE) or scleroderma in a subject are provided. Particularly, the present invention relates to a specific antibody reactivity profile useful in diagnosing SLE or scleroderma in a subject.

Abstract translation: 提供了用于诊断受试者系统性红斑狼疮（SLE）或硬皮病的方法和试剂盒。 特别地，本发明涉及可用于诊断受试者中的SLE或硬皮病的特异性抗体反应性分布。

公开(公告)号：US20200225223A1

公开(公告)日：2020-07-16

申请号：US16748001

申请日：2020-01-21

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Irun R. COHEN ,  Eytan DOMANY ,  Francisco Javier QUINTANA ,  Guy HED ,  Gad GETZ

IPC: G01N33/564 ,  G16B20/00 ,  G01N33/68

Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.

公开(公告)号：US20140229116A1

公开(公告)日：2014-08-14

申请号：US14180374

申请日：2014-02-14

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Eytan DOMANY ,  Michal SHEFFER ,  Shlomo URBACH ,  Yotam DRIER

IPC: G06F19/24

CPC classification number: G16B40/00

Abstract: A system and method for non-linear quantification of pathway deregulation in an individual biological sample for analysis of malignancies.

Abstract translation: 用于非线性量化用于分析恶性肿瘤的个体生物样品中的途径去调节的系统和方法。

公开(公告)号：US20200264172A1

公开(公告)日：2020-08-20

申请号：US16751831

申请日：2020-01-24

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Irun R. COHEN ,  Eytan DOMANY ,  Noam SHENTAL ,  Ittai FATTAL

IPC: G01N33/564 ,  A61K31/711 ,  C12Q1/6883

Abstract: Methods and kits for diagnosing systemic lupus erythematosus (SLE) in a subject are provided. Particularly, the present invention relates to specific oligonucleotide antibody reactivities useful in diagnosing SLE in a subject.

公开(公告)号：US20190004045A1

公开(公告)日：2019-01-03

申请号：US16123385

申请日：2018-09-06

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Irun R. COHEN ,  Eytan DOMANY ,  Francisco Javier QUINTANA ,  Guy HED ,  Gad GETZ

IPC: G01N33/564 ,  G01N33/68 ,  G06F19/18

Abstract: Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.