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1.发明授权Fused ring compound containing furan or salt thereof and pharmaceutical composition comprising same 有权含有呋喃或其盐的稠环化合物和包含其的药物组合物公开(公告)号：US09493478B2
公开(公告)日：2016-11-15
申请号：US14416079
申请日：2013-07-23
申请人： YUHAN CORPORATION
发明人： Hyoung Sig Seo , Tae Kyun Kim , Hyun Joo Lee , Dong Hoon Kim , Gyu Jin Lee , Jun Chul Park , Ji Yeong Gal , Tae-hoon Kim , Kwan Hoon Hyun , Kyoung Kyu Ahn , Kaapjoo Park , Su Youn Nam , Ge Hyeong Lee , Hee Jong Lim
IPC分类号： C07D491/048
CPC分类号： C07D491/048
摘要： The present invention provides a fused ring compound containing furan or a pharmaceutically acceptable salt thereof, a method for preparing same, a pharmaceutical composition comprising same, and a use thereof. The fused ring compound containing furan or a pharmaceutically acceptable salt thereof inhibits the activity of phosphatidylinositol 3-kinase (PI3K) and can therefore be used in a pharmaceutical composition for treating and preventing respiratory diseases, inflammatory diseases, proliferative diseases, cardiovascular diseases, or central nervous system diseases which occur due to the over-activation of PI3K.
摘要翻译： 本发明提供含有呋喃或其药学上可接受的盐的稠环化合物，其制备方法，包含其的药物组合物及其用途。 含有呋喃或其药学上可接受的盐的稠环化合物抑制磷脂酰肌醇3-激酶（PI3K）的活性，因此可用于治疗和预防呼吸系统疾病，炎性疾病，增殖性疾病，心血管疾病或中枢的药物组合物 由于PI3K的过度激活而发生的神经系统疾病。
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2.发明申请FUSED RING COMPOUND CONTAINING FURAN OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 有权含有FURAN或其盐的熔融环化合物和包含其的药物组合物公开(公告)号：US20150191478A1
公开(公告)日：2015-07-09
申请号：US14416079
申请日：2013-07-23
申请人： YUHAN CORPORATION
发明人： Hyoung Sig Seo , Tae Kyun Kim , Hyun Joo Lee , Dong Hoon Kim , Gyu Jin Lee , Jun Chul Park , Ji Yeong Gal , Tae-hoon Kim , Kwan Hoon Hyun , Kyoung Kyu Ahn , Kaapjoo Park , Su Youn Nam , Ge Hyeong Lee , Hee Jong Lim
IPC分类号： C07D491/048
CPC分类号： C07D491/048
摘要： The present invention provides a fused ring compound containing furan or a pharmaceutically acceptable salt thereof, a method for preparing same, a pharmaceutical composition comprising same, and a use thereof. The fused ring compound containing furan or a pharmaceutically acceptable salt thereof inhibits the activity of phosphatidylinositol 3-kinase (PI3K) and can therefore be used in a pharmaceutical composition for treating and preventing respiratory diseases, inflammatory diseases, proliferative diseases, cardiovascular diseases, or central nervous system diseases which occur due to the over-activation of PI3K.
摘要翻译： 本发明提供含有呋喃或其药学上可接受的盐的稠环化合物，其制备方法，包含其的药物组合物及其用途。 含有呋喃或其药学上可接受的盐的稠环化合物抑制磷脂酰肌醇3-激酶（PI3K）的活性，因此可用于治疗和预防呼吸系统疾病，炎性疾病，增殖性疾病，心血管疾病或中枢的药物组合物 由于PI3K的过度激活而发生的神经系统疾病。
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