公开(公告)号：US20130260386A1

公开(公告)日：2013-10-03

申请号：US13914686

申请日：2013-06-11

Applicant: Yeda Research and Development Co., Ltd.

Inventor： Lior NISSIM ,  Roy Bar-Ziv

IPC: C12Q1/68

CPC classification number: C12Q1/6897 ,  C12N15/1055 ,  C12N15/85 ,  C12N2830/007 ,  C12N2830/008 ,  G01N33/5008 ,  G01N33/5091

Abstract: Nucleic acid construct systems are disclosed capable of diagnosing and treating a cell state (e.g. disease state). Methods of diagnosing and treating disease states using the nucleic acid constructs described herein are also disclosed. In addition, methods of screening for agents capable of reversing a disease phenotype using the nucleic acid constructs of the present invention are disclosed.

Abstract translation: 公开了能够诊断和治疗细胞状态（例如疾病状态）的核酸构建系统。 还公开了使用本文所述的核酸构建体诊断和治疗疾病状态的方法。 此外，公开了使用本发明的核酸构建体筛选能够逆转疾病表型的试剂的方法。

公开(公告)号：US12172159B2

公开(公告)日：2024-12-24

申请号：US17029228

申请日：2020-09-23

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Roy Bar-Ziv ,  Alexandra Tayar ,  Shirley Shulman Daube ,  Yuval Efrath ,  Michael Levy

IPC: B01L3/00 ,  C12N13/00 ,  C12N15/10 ,  G01N27/447

Abstract: Methods of controlling biological processes by altering the electric field gradient in a test chamber are disclosed. A portion of a surface of the test chamber is attached to at least one immobilized component of the biological process. Microfluidic devices capable of same are also disclosed.