公开(公告)号：US09695402B2

公开(公告)日：2017-07-04

申请号：US15022280

申请日：2014-09-15

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Rony Seger ,  Alexander Plotnikov

IPC: A61K38/12 ,  C12N9/12 ,  A61K38/00

CPC classification number: C12N9/12 ,  A61K38/00 ,  A61K38/12 ,  A61K47/64 ,  C12N9/1205 ,  C12Y207/11 ,  C12Y207/11024

Abstract: An isolated peptide being no longer than 20 amino acids comprising a sequence at least 95% homologous to the sequence GQLNHILGILGX1PX2QED (SEQ ID NO: 4), wherein X1 and X2 are any amino acid, the peptide being capable of preventing extracellular signal-regulated kinase1/2 (ERK) translocation into the nucleus.

公开(公告)号：US10240133B2

公开(公告)日：2019-03-26

申请号：US15498493

申请日：2017-04-27

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Rony Seger ,  Alexander Plotnikov

IPC: A61K38/12 ,  C12N9/12 ,  A61K47/64 ,  A61K38/00

Abstract: An isolated peptide being no longer than 20 amino acids comprising a sequence at least 95% homologous to the sequence GQLNHILGILGX1PX2QED (SEQ ID NO: 4), wherein X1 and X2 are any amino acid, the peptide being capable of preventing extracellular signal-regulated kinase1/2 (ERK) translocation into the nucleus.