公开(公告)号：US10159717B2

公开(公告)日：2018-12-25

申请号：US14685628

申请日：2015-04-14

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Vivian I. Teichberg ,  Angela Ruban

IPC: A61K38/43 ,  A61K38/45 ,  A61K31/194 ,  A61K31/495 ,  A61K38/44 ,  A61K31/19 ,  A61K38/51 ,  A61K38/52 ,  A61K38/53 ,  A61K31/198

Abstract: A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent which reduces blood glutamate levels and enhances brain to blood glutamate efflux to thereby treat the cancer of the central nervous system in the subject.

公开(公告)号：US20150216949A1

公开(公告)日：2015-08-06

申请号：US14685628

申请日：2015-04-14

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Vivian I. Teichberg ,  Angela Ruban

IPC: A61K38/45 ,  A61K31/495

CPC classification number: A61K38/45 ,  A61K31/19 ,  A61K31/194 ,  A61K31/198 ,  A61K31/495 ,  A61K38/44 ,  A61K38/51 ,  A61K38/52 ,  A61K38/53 ,  C12Y206/01001 ,  C12Y206/01002

Abstract: A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent which reduces blood glutamate levels and enhances brain to blood glutamate efflux to thereby treat the cancer of the central nervous system in the subject.

Abstract translation: 提供了在有需要的对象中治疗中枢神经系统癌症的方法。 该方法包括向受试者施用治疗有效量的降低血液谷氨酸水平并增强脑与血液谷氨酸流出的试剂，从而治疗受试者中的中枢神经系统的癌症。