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公开(公告)号:US20210403518A1
公开(公告)日:2021-12-30
申请号:US17478926
申请日:2021-09-19
Applicant: Yeda Research and Development Co. Ltd.
Inventor: Ofer YIZHAR , Mathias MAHN
Abstract: Bistable type II opsins are provided. Accordingly, there is provided a polypeptide comprising a bistable type II opsin and a heterologous ER export signal and/or membrane trafficking signal. Also provided are polynucleotides encoding same, cells expressing same and methods of use thereof.