-
公开(公告)号：US09840711B2
公开(公告)日：2017-12-12
申请号：US15442784
申请日：2017-02-27
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yosef Shaul , Peter Tsvetkov , Julia Adler
IPC: A61K48/00 , C12N15/113
CPC classification number: C12N15/1137 , A61K31/713 , C12N15/1135 , C12N2310/14 , C12Q1/025 , C12Q1/68 , G01N33/5011 , G01N2333/4703 , G01N2500/04 , G01N2500/10
Abstract: A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an agent which induces a dissociation of the 26S proteasomal complex into a 20S component and a 19S component to thereby inhibit 26S proteasomal activity, wherein the pharmaceutical agent is devoid of a chemotherapeutic agent.
-
公开(公告)号：US09579339B2
公开(公告)日：2017-02-28
申请号：US14866957
申请日：2015-09-27
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yosef Shaul , Peter Tsvetkov , Julia Adler
IPC: A61K48/00 , A61K31/713 , C12N15/113 , C12Q1/02 , C12Q1/68 , G01N33/50
CPC classification number: C12N15/1137 , A61K31/713 , C12N15/1135 , C12N2310/14 , C12Q1/025 , C12Q1/68 , G01N33/5011 , G01N2333/4703 , G01N2500/04 , G01N2500/10
Abstract: A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an agent which induces a dissociation of the 26S proteasomal complex into a 20S component and a 19S component to thereby inhibit 26S proteasomal activity, wherein the pharmaceutical agent is devoid of a chemotherapeutic agent.
Abstract translation: 公开了一种治疗癌症的方法。 该方法包括向受试者施用治疗有效量的药物组合物，其包含诱导26S蛋白酶体复合体解离成20S组分和19S组分从而抑制26S蛋白酶体活性的试剂，其中所述药剂没有 化疗剂。
-
Patent Agency Ranking
公开(公告)号：US20160008390A1
公开(公告)日：2016-01-14
申请号：US14866957
申请日：2015-09-27
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yosef SHAUL , Peter Tsvetkov , Julia Adler
IPC: A61K31/713 , C12N15/113 , G01N33/50
CPC classification number: C12N15/1137 , A61K31/713 , C12N15/1135 , C12N2310/14 , C12Q1/025 , C12Q1/68 , G01N33/5011 , G01N2333/4703 , G01N2500/04 , G01N2500/10
Abstract: A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an agent which induces a dissociation of the 26S proteasomal complex into a 20S component and a 19S component to thereby inhibit 26S proteasomal activity, wherein the pharmaceutical agent is devoid of a chemotherapeutic agent.
Abstract translation: 公开了一种治疗癌症的方法。 该方法包括向受试者施用治疗有效量的药物组合物，其包含诱导26S蛋白酶体复合体解离成20S组分和19S组分从而抑制26S蛋白酶体活性的试剂，其中所述药剂没有 化疗剂。
-
公开(公告)号：US10155949B2
公开(公告)日：2018-12-18
申请号：US15834110
申请日：2017-12-07
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yosef Shaul , Peter Tsvetkov , Julia Adler
IPC: A61K48/00 , C12N15/113 , A61K31/713 , C12Q1/02 , C12Q1/68 , G01N33/50
Abstract: A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an agent which induces a dissociation of the 26S proteasomal complex into a 20S component and a 19S component to thereby inhibit 26S proteasomal activity, wherein the pharmaceutical agent is devoid of a chemotherapeutic agent.
-
公开(公告)号：US20180087057A1
公开(公告)日：2018-03-29
申请号：US15834110
申请日：2017-12-07
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yosef Shaul , Peter Tsvetkov , Julia Adler
IPC: C12N15/113
CPC classification number: C12N15/1137 , A61K31/713 , C12N15/1135 , C12N2310/14 , C12Q1/025 , C12Q1/68 , G01N33/5011 , G01N2333/4703 , G01N2500/04 , G01N2500/10
Abstract: A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an agent which induces a dissociation of the 26S proteasomal complex into a 20S component and a 19S component to thereby inhibit 26S proteasomal activity, wherein the pharmaceutical agent is devoid of a chemotherapeutic agent.
-
公开(公告)号：US09145559B2
公开(公告)日：2015-09-29
申请号：US14354580
申请日：2012-10-25
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yosef Shaul , Peter Tsvetkov , Julia Adler
IPC: A61K48/00 , C12N15/113 , A61K31/713 , C12Q1/02 , C12Q1/68
CPC classification number: C12N15/1137 , A61K31/713 , C12N15/1135 , C12N2310/14 , C12Q1/025 , C12Q1/68 , G01N33/5011 , G01N2333/4703 , G01N2500/04 , G01N2500/10
Abstract: A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an agent which induces a dissociation of the 26S proteasomal complex into a 20S component and a 19S component to thereby inhibit 26S proteasomal activity, wherein the pharmaceutical agent is devoid of a chemotherapeutic agent.
Abstract translation: 公开了一种治疗癌症的方法。 该方法包括向受试者施用治疗有效量的药物组合物，其包含诱导26S蛋白酶体复合体解离成20S组分和19S组分从而抑制26S蛋白酶体活性的试剂，其中所述药剂没有 化疗剂。
-
公开(公告)号：US20140288157A1
公开(公告)日：2014-09-25
申请号：US14354580
申请日：2012-10-25
Applicant: Yeda Research and Development Co. Ltd.
Inventor： Yosef Shaul , Peter Tsvetkov , Julia Adler
IPC: C12N15/113 , C12Q1/68 , C12Q1/02
CPC classification number: C12N15/1137 , A61K31/713 , C12N15/1135 , C12N2310/14 , C12Q1/025 , C12Q1/68 , G01N33/5011 , G01N2333/4703 , G01N2500/04 , G01N2500/10
Abstract: A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising an agent which induces a dissociation of the 26S proteasomal complex into a 20S component and a 19S component to thereby inhibit 26S proteasomal activity, wherein the pharmaceutical agent is devoid of a chemotherapeutic agent.
Abstract translation: 公开了一种治疗癌症的方法。 该方法包括向受试者施用治疗有效量的药物组合物，其包含诱导26S蛋白酶体复合体解离成20S组分和19S组分从而抑制26S蛋白酶体活性的试剂，其中所述药剂没有 化疗剂。
-
-
-
-
-
-
Search Results
7
records
(took 0.028 seconds)
