公开(公告)号：US20140243393A1

公开(公告)日：2014-08-28

申请号：US14277825

申请日：2014-05-15

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Eran HORNSTEIN ,  Alon Chen ,  Sharon Haramati ,  Elik Chapnik

IPC: C12N15/113

CPC classification number: C12N15/113 ,  A61K31/7088

Abstract: Use of an agent which upregulates an activity or amount of miRNA-9 or miRNA-9* is disclosed for the preparation of a medicament for the treatment of a motor neuron disease (MND).

Abstract translation: 公开了用于制备用于治疗运动神经元疾病（MND）的药物的上调miRNA-9或miRNA-9 *的活性或量的药剂的用途。

公开(公告)号：US09359607B2

公开(公告)日：2016-06-07

申请号：US14277825

申请日：2014-05-15

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Eran Hornstein ,  Alon Chen ,  Sharon Haramati ,  Elik Chapnik

IPC: C12N15/113 ,  C12Q1/68 ,  A61P25/02 ,  A61K31/7088

CPC classification number: C12N15/113 ,  A61K31/7088

Abstract: Use of an agent which upregulates an activity or amount of miRNA-9 or miRNA-9* is disclosed for the preparation of a medicament for the treatment of a motor neuron disease (MND).

Abstract translation: 公开了用于制备用于治疗运动神经元疾病（MND）的药物的上调miRNA-9或miRNA-9 *的活性或量的试剂的用途。

公开(公告)号：US09901593B2

公开(公告)日：2018-02-27

申请号：US14856697

申请日：2015-09-17

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Alon Chen ,  Eran Hornstein ,  Orna Issler ,  Sharon Haramati ,  Naama Volk

IPC: C12N15/11 ,  A61K31/7105 ,  A61K31/713 ,  C12N15/113 ,  C12Q1/68 ,  A61K48/00

CPC classification number: A61K31/7105 ,  A61K31/713 ,  A61K48/0058 ,  C12N15/113 ,  C12N2310/141 ,  C12Q1/6883 ,  C12Q2600/178

Abstract: microRNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone-associated medical conditions are provided.

公开(公告)号：US12016876B2

公开(公告)日：2024-06-25

申请号：US17734199

申请日：2022-05-02

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Alon Chen ,  Eran Hornstein ,  Orna Issler ,  Sharon Haramati ,  Naama Volk

IPC: C12N15/11 ,  A61K31/7105 ,  A61K31/713 ,  A61K48/00 ,  C12N15/113 ,  C12Q1/6883

CPC classification number: A61K31/7105 ,  A61K31/713 ,  A61K48/0058 ,  C12N15/113 ,  C12Q1/6883 ,  C12N2310/141 ,  C12Q2600/178

Abstract: microRNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone-associated medical conditions are provided.

公开(公告)号：US10238681B2

公开(公告)日：2019-03-26

申请号：US15873998

申请日：2018-01-18

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Alon Chen ,  Eran Hornstein ,  Orna Issler ,  Sharon Haramati ,  Naama Volk

IPC: C12N15/11 ,  A61K31/7105 ,  A61K31/713 ,  C12N15/113 ,  C12Q1/6883 ,  A61K48/00

Abstract: microRNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone-associated medical conditions are provided.