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1.发明授权Application of highly conserved domain sequences from viral genome as template to design therapeutic slirnas 有权将来自病毒基因组的高度保守的结构域序列应用于模板，设计治疗性疾病公开(公告)号：US08217163B2
公开(公告)日：2012-07-10
申请号：US12886446
申请日：2010-09-20
申请人： York Yuan Yuan Zhu , Li Chen , TieJun Li , YiXiang Lu , YunCheng Sun , Jinkang Wang
发明人： York Yuan Yuan Zhu , Li Chen , TieJun Li , YiXiang Lu , YunCheng Sun , Jinkang Wang
CPC分类号： C12N15/115 , A61K31/713 , C12N2310/13 , C12N2310/16 , Y02A50/465
摘要： This invention relates to the application of the highly conserved sequences of viral genome, especially from a highly conserved domain of enteroviral genome as templates to design target small ligand RNAs (sliRNAs). The resulting sliRNAs are therapeutically active ingredients in the treatment of the related diseases caused by pathological angiogenesis.
摘要翻译： 本发明涉及病毒基因组的高度保守序列的应用，特别是来自肠道病毒基因组的高度保守结构域作为模板来设计靶小配体RNA（sliRNA）。 所得的sliRNA是治疗由病理性血管发生引起的相关疾病的治疗活性成分。
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2.发明申请Application of Highly Conserved Domain Sequences From Viral Genome As Template To Design Therapeutic Slirnas 有权应用病毒基因组的高保守域序列作为设计治疗性Slirnas的模板公开(公告)号：US20120071542A1
公开(公告)日：2012-03-22
申请号：US12886446
申请日：2010-09-20
申请人： York YuanYuan Zhu , Li Chen , TieJun Li , YiXiang Lu , YunCheng Sun , Jinkang Wang
发明人： York YuanYuan Zhu , Li Chen , TieJun Li , YiXiang Lu , YunCheng Sun , Jinkang Wang
IPC分类号： A61K31/713 , A61P27/02 , A61P35/00 , C07H21/02 , C12Q1/68
CPC分类号： C12N15/115 , A61K31/713 , C12N2310/13 , C12N2310/16 , Y02A50/465
摘要： This invention relates to the application of the highly conserved sequences of viral genome, especially from a highly conserved domain of enteroviral genome as templates to design target small ligand RNAs (sliRNAs). The resulting sliRNAs are therapeutically active ingredients in the treatment of the related diseases caused by pathological angiogenesis.
摘要翻译： 本发明涉及病毒基因组的高度保守序列的应用，特别是来自肠道病毒基因组的高度保守结构域作为模板来设计靶小配体RNA（sliRNA）。 所得的sliRNA是治疗由病理性血管发生引起的相关疾病的治疗活性成分。
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