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公开(公告)号:US20130303600A1
公开(公告)日:2013-11-14
申请号:US13941932
申请日:2013-07-15
申请人: Young-Hoon JI , Dong-Hee KIM , Jung-Ae KIM , Jae-Seon KANG , Sung-Uk CHUNG , Sung-Woo HWANG , Kyung-Ran KANG , You-Ra KANG
发明人: Young-Hoon JI , Dong-Hee KIM , Jung-Ae KIM , Jae-Seon KANG , Sung-Uk CHUNG , Sung-Woo HWANG , Kyung-Ran KANG , You-Ra KANG
IPC分类号: A61K31/365
CPC分类号: A61K31/365 , A61K31/335
摘要: The present invention relates to an anti-angiogenic composition containing macrolactin compounds such as macrolactin A, 7-O-malonyl macrolactin A, and 7-O-succinyl macrolactin A as active ingredients. The macrolactin compounds according to the present invention strongly suppress angiogenesis in in vivo experiments and can be used as a pharmaceutical composition for preventing or treating diseases caused by angiogenesis.