公开(公告)号：US20060058377A1

公开(公告)日：2006-03-16

申请号：US11083371

申请日：2005-03-18

申请人： Yu-Dong Zhou ,  Dale Nagle ,  Asjad Mohammed ,  Chowdhury Hossain

发明人： Yu-Dong Zhou ,  Dale Nagle ,  Asjad Mohammed ,  Chowdhury Hossain

IPC分类号： A61K31/343 ,  C07D493/04

CPC分类号： C07D493/06

摘要： Compounds and compositions of the following formula: and analogs and stereoisomers thereof (and pharmaceutically acceptable carriers). Additionally disclosed is a method of inhibiting hypoxia-inducible factor-1 function in a patient or sample thereof, comprising administering to the patient or sample an effective inhibiting amount of a compound or composition of the present invention.

摘要翻译： 下式的化合物和组成：