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1.发明申请Muscarinic Receptor Agonists that are Effective in the Treatment of Pain, Alzheimer's Disease and Schizophrenia 审中-公开有效治疗疼痛，阿尔茨海默病和精神分裂症的毒蕈碱受体激动剂公开(公告)号：US20100173935A1
公开(公告)日：2010-07-08
申请号：US12303641
申请日：2007-06-08
IPC分类号： A61K31/454 , C07D401/14 , C07D405/14 , C07D451/04 , A61K31/46 , A61P25/28 , A61P25/18 , A61P25/22 , A61P25/24 , A61P29/00
CPC分类号： C07D401/14 , C07D405/14 , C07D451/04
摘要： Compounds of Formula IA, or pharmaceutically acceptable salts thereof: IA wherein G1, G2, G3, G4, R1, R2, X, Y, Z and n are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 式IA化合物或其药学上可接受的盐：其中G1，G2，G3，G4，R1，R2，X，Y，Z和n如说明书中所定义，以及包括化合物的盐和药物组合物的制备 。 它们可用于治疗，特别是治疗疼痛。
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公开(公告)号：US07956069B2
公开(公告)日：2011-06-07
申请号：US11760011
申请日：2007-06-08
IPC分类号： A61K31/454 , C07D403/14
CPC分类号： C07D401/14 , C07D405/14 , C07D409/14
摘要： Compounds of Formulae I, or pharmaceutically acceptable salts thereof: wherein A1, A2, G1, G2 G3, R1, R2, X, Y, Z, m, n and p are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 式I化合物或其药学上可接受的盐：其中A1，A2，G1，G2 G3，R1，R2，X，Y，Z，m，n和p如说明书中所定义，以及盐和药物组合物，包括 制备化合物。 它们可用于治疗，特别是治疗疼痛。
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公开(公告)号：US20070287695A1
公开(公告)日：2007-12-13
申请号：US11760011
申请日：2007-06-08
IPC分类号： A61K31/4545 , A61K31/454 , C07D403/14
CPC分类号： C07D401/14 , C07D405/14 , C07D409/14
摘要： Compounds of Formulae I, or pharmaceutically acceptable salts thereof: wherein A1, A2, G1, G2 G3, R1, R2, X, Y, Z, m, n and p are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 式I的化合物或其药学上可接受的盐：其中A 1，A 2，G 1，G 2， R 3，R 1，R 2，X 2，X，Y，Z，m，n和p如本说明书中所定义 因为制备包括这些化合物的盐和药物组合物。 它们可用于治疗，特别是治疗疼痛。
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4.发明申请MUSCARINIC RECEPTOR AGONISTS, COMPOSITIONS, METHODS OF TREATMENT THEREOF, AND PROCESSES FOR PREPARATION THEREOF 177 审中-公开肌钙蛋白受体激动剂，组合物，其治疗方法及其制备方法177公开(公告)号：US20090221567A1
公开(公告)日：2009-09-03
申请号：US12392219
申请日：2009-02-25
申请人： Yun-Xing Cheng , Xuehong Luo , Mehrnaz Pourashraf , Vijayaratnam Santhakumar , Miroslaw Jerzy Tomaszewski
发明人： Yun-Xing Cheng , Xuehong Luo , Mehrnaz Pourashraf , Vijayaratnam Santhakumar , Miroslaw Jerzy Tomaszewski
IPC分类号： A61K31/536 , C07D401/14 , C07D413/14 , A61K31/517 , A61P25/18 , A61P25/28 , A61P29/00 , A61P25/22 , A61P25/24
CPC分类号： C07D401/14 , C07D413/14 , C07D417/14
摘要： Compounds of Formula I, or pharmaceutically acceptable salts thereof: wherein Y, X, A, R1, R2, m, p, and q are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 式I化合物或其药学上可接受的盐：其中Y，X，A，R 1，R 2，m，p和q如本说明书中所定义，以及包括该化合物的盐和药物组合物的制备。 它们可用于治疗，特别是治疗疼痛。
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