公开(公告)号：US06699992B2

公开(公告)日：2004-03-02

申请号：US10344643

申请日：2003-02-12

申请人： Yuncai Wang ,  Rongye Chen ,  Haijun Nan

发明人： Yuncai Wang ,  Rongye Chen ,  Haijun Nan

IPC分类号： C07D21556

CPC分类号： C07D215/56 ,  C07C49/807

摘要： The present invention provides a process for preparing quinolonecarboxylic acid derivatives having the formula (I): wherein R1 is H, halogen, or amino; R2 is halogen; R3 is H, halogen, C1-4 alkoxyl, or CN; R4 is selected from the group consisting of C3-6cycloalkyl, C1-4alkyl, C1-4alkoxyC1-4alkyl, and C1-4alkylaminoC1-4alkyl. The invention also provides new acetophenones having the formula (II) that are intermediates for preparing the compound of the formula (I).

摘要翻译： 本发明提供了制备具有式（I）的喹诺酮羧酸衍生物的方法：其中R1是H，卤素或氨基; R2是卤素; R3是H，卤素，C1-4烷氧基或CN; R 4选自C 3-6环烷基，C 1-4烷基，C 1-4烷氧基C 1-4烷基和C 1-4烷基氨基C 1-4烷基。 本发明还提供了具有式（II）的新的苯乙酮，它是制备式（I）化合物的中间体。