公开(公告)号：US5442077A

公开(公告)日：1995-08-15

申请号：US285719

申请日：1994-08-04

申请人： Yutaka Baba ,  Toshinao Usui ,  Noriyuki Iwata ,  Takuji Kakigami ,  Yoshiro Ozeki ,  Katsura Tsukamoto ,  Nobuyuki Ito

发明人： Yutaka Baba ,  Toshinao Usui ,  Noriyuki Iwata ,  Takuji Kakigami ,  Yoshiro Ozeki ,  Katsura Tsukamoto ,  Nobuyuki Ito

IPC分类号： A61K31/40 ,  A61P1/00 ,  C07D487/04

CPC分类号： C07D487/04

摘要： There are disclosed a benzo[b]furancarboxamide derivative of the formula ##STR1## wherein R.sup.a, R.sup.b, R.sup.c and R.sup.d are a hydrogen atom or lower alkyl group, respectively; R.sup.e is a hydrogen atom, amino radical, lower alkylamino group or acylamino group; X is a hydrogen atom or halogen atom; and n is an integer of 1-5,and including racemic compounds and stereo-isomers thereof, a salt of the compounds, a process for the preparation of the compounds and salts as well as use thereof for improving hypermotility.

摘要翻译： 公开了式（I）的苯并[b]呋喃甲酰胺衍生物，其中R a，R b，R c和R d分别是氢原子或低级烷基; Re为氢原子，氨基，低级烷基氨基或酰氨基; X是氢原子或卤素原子; n为1-5的整数，并且包括外消旋化合物及其立体异构体，化合物的盐，化合物和盐的制备方法以及其用于改善过度运动性的用途。

公开(公告)号：US5539125A

公开(公告)日：1996-07-23

申请号：US489709

申请日：1995-06-13

申请人： Yutaka Baba ,  Toshinao Usui ,  Takuji Kakigami ,  Yoshiro Ozeki ,  Katsura Tsukamoto ,  Nobuyuki Itoh

发明人： Yutaka Baba ,  Toshinao Usui ,  Takuji Kakigami ,  Yoshiro Ozeki ,  Katsura Tsukamoto ,  Nobuyuki Itoh

IPC分类号： A61K31/40 ,  A61P1/00 ,  C07D487/04 ,  C07D403/12 ,  C07D405/12

CPC分类号： C07D487/04

摘要： There are disclosed a 1-azabicyclo[3.3.0]octan derivative of the formula ##STR1## wherein n is an integer of 1-5; and Ar is an aromatic residue. a pharmacologically acceptable salt of the compound, a process for the preparation of the compound and salt as well as use thereof as hypermotility agents.

摘要翻译： 公开了式（I）的1-氮杂双环[3.3.0]辛烷衍生物，其中n是1-5的整数; 并且Ar是芳族残基。 化合物的药理学上可接受的盐，化合物和盐的制备方法以及其作为超运动剂的用途。

公开(公告)号：US5502209A

公开(公告)日：1996-03-26

申请号：US489770

申请日：1995-06-13

申请人： Yutaka Baba ,  Toshinao Usui ,  Takuji Kakigami ,  Yoshiro Ozeki ,  Katsura Tsukamoto ,  Nobuyuki Asaeda ,  Nobuyuki Itoh

发明人： Yutaka Baba ,  Toshinao Usui ,  Takuji Kakigami ,  Yoshiro Ozeki ,  Katsura Tsukamoto ,  Nobuyuki Asaeda ,  Nobuyuki Itoh

IPC分类号： A61K31/40 ,  A61P1/00 ,  C07D487/04 ,  C07D471/06

CPC分类号： C07D487/04

摘要： There are disclosed a benzopyrancarboxamide derivative of the formula ##STR1## wherein R.sup.1 is hydrogen atom or a lower alkyl group; R.sup.2 is hydrogen atom, a lower alkyl group, halogen atom, an amino radical or an acylamino group; R.sup.3 is hydrogen atom, a lower alkyl group, a lower alkoxy group or halogen atom; dotted line is a possible double bond; and n is an integer of 1-5,and a pharmacologically acceptable salt of the compound, a process for the preparation of the compound and salt as well as use thereof.

摘要翻译： 公开了式（I）的苯并吡喃甲酰胺衍生物，其中R 1是氢原子或低级烷基; R2是氢原子，低级烷基，卤素原子，氨基或酰氨基; R3是氢原子，低级烷基，低级烷氧基或卤素原子; 虚线是可能的双重键; 和n为1-5的整数，化合物的药理学上可接受的盐，化合物和盐的制备方法及其用途。