公开(公告)号：US20250125003A1

公开(公告)日：2025-04-17

申请号：US18608945

申请日：2024-03-19

Applicant: ZHEJIANG LAB

Inventor： Zenghui XU ,  Jin TANG ,  Yu ZHANG ,  Gaoxiang CHEN ,  Ting YU ,  Jin ZHAO ,  Ji ZHANG

IPC: G16B15/00

Abstract: A graph calculation method of RNA similarity analysis, an apparatus, a device, and a medium are provided. The method includes: converting sequence data of a looked-up RNA into a looked-up RNA structure graph; obtain a first similarity between the looked-up RNA structure graph and a target RNA structure graph; obtaining a second similarity based on the number of base constituent structures in the looked-up RNA structure graph and the number of base constituent structures in the target RNA structure graph; reconstructing the looked-up RNA structure graph based on the base constituent structures in the looked-up RNA structure graph to generate a looked-up RNA higher-order graph; and analyzing similarity between the looked-up RNA higher-order graph and a target RNA higher-order graph to obtain a third similarity; and obtaining a final similarity between the looked-up RNA and the target RNA based on the first similarity, the second similarity, and the third similarity.