公开(公告)号：US20220096595A1

公开(公告)日：2022-03-31

申请号：US17427109

申请日：2020-03-30

Applicant: ZHENGZHOU UNIVERSITY

Inventor： Qiaozhen KANG ,  Xin LIU ,  Jike LU ,  Zhenyu JI ,  Ting WANG ,  Juanjuan YI ,  Chenglong ZHANG ,  Xun GUO

IPC: A61K38/17 ,  A61P17/04

Abstract: Provided is an anti-atopic dermatitis protein. A corresponding pharmaceutical composition contains a pharmaceutically acceptable carrier and the anti-atopic dermatitis protein. The anti-atopic dermatitis protein is one or more proteins selected from the group consisting of Helicobacter pylori-neutrophil-activating protein (HP-NAP) and recombinant maltose-binding protein fused to neutrophil-activating protein (rMBP-NAP). HP-NAP and rMBP-NAP can effectively treat AD in an oxazolone-induced AD model, providing brand-new drugs for the treatment of AD.