公开(公告)号：US4064200A

公开(公告)日：1977-12-20

申请号：US648756

申请日：1976-01-13

申请人： Zenichi Sato ,  Fumio Shimizu ,  Shoji Kusano ,  Keiichiro Takagi ,  Yoji Imamiya

发明人： Zenichi Sato ,  Fumio Shimizu ,  Shoji Kusano ,  Keiichiro Takagi ,  Yoji Imamiya

IPC分类号： C07F9/165 ,  C07F9/17

CPC分类号： C07F9/17 ,  C07F9/1653

摘要： O,O-Dialkyl-S-benzyl thiophosphates are obtained by reacting a diester of phosphorous acid such as dimethyl phosphite or diethyl phosphite, in an organic solvent such as toluene or xylene which is sparingly soluble or insoluble in water, with sulfur and an alkali or alkaline earth metal hydroxide or oxide such as NaOH or Ca(OH).sub.2, extracting the reaction product with water and then reacting the extract with a benzyl halide. In this manner, O,O-dialkyl-S-benzyl thiophosphates useful as agricultural and horticultural bactericidal and insecticidal agents are industrially advantageously obtained in a high purity and in a high yield.

摘要翻译： O，O-二烷基-S-苄基硫代磷酸酯通过亚磷酸二酯或亚磷酸二乙酯在有机溶剂如甲苯或微溶于水或不溶于水的二甲苯与硫和碱反应得到， 或碱土金属氢氧化物或氧化物如NaOH或Ca（OH）2，用水萃取反应产物，然后使提取物与苄基卤反应。 以这种方式，用作农业和园艺杀菌和杀虫剂的O，O-二烷基-S-苄基硫代磷酸盐在工业上有利地以高纯度和高产率获得。

公开(公告)号：US4248779A

公开(公告)日：1981-02-03

申请号：US948346

申请日：1978-10-04

申请人： Zenichi Sato ,  Fumiya Tabuchi ,  Keiichiro Takagi ,  Yoji Imamiya

发明人： Zenichi Sato ,  Fumiya Tabuchi ,  Keiichiro Takagi ,  Yoji Imamiya

IPC分类号： A01N47/10 ,  C07C67/00 ,  C07C325/00 ,  C07C333/04 ,  C07D295/21 ,  C07C155/03 ,  C07D207/32 ,  C07D295/10 ,  C07D211/06

CPC分类号： C07D295/21

摘要： A thiolcarbamate having the formula ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and respectively represent an alkyl, alkoxy, alkenyl, cycloalkyl, hydroxyalkyl, phenyl or benzyl group and R.sub.1 and R.sub.2 can form a ring by binding each other with or without oxygen atom; and R.sub.3 represents a lower alkyl or benzyl group or a substituted benzyl group having one or two substituent of halogen atom, alkyl, alkoxy, alkylthio, nitro, or cyano group, which comprises reacting carbonyl sulfide with a sec-amine having the formula ##STR2## wherein R.sub.1 and R.sub.2 are defined above, in an aqueous medium and then reacting a halogenated hydrocarbon having the formulaX--R.sub.3 (IV)wherein R.sub.3 is defined above and X represents a halogen atom, in an aqueous medium.

摘要翻译： 具有式（VI）的硫代氨基甲酸酯其中R 1和R 2相同或不同并分别表示烷基，烷氧基，烯基，环烷基，羟基烷基，苯基或苄基，并且R 1和R 2可以通过彼此结合而形成环 有或没有氧原子; 并且R 3表示低级烷基或苄基或具有一个或两个卤原子，烷基，烷氧基，烷硫基，硝基或氰基取代基的取代苄基，其包括使硫化羰与具有式 （I）其中R 1和R 2如上定义，在水性介质中，然后在水性介质中使具有式X-R3（Ⅳ）的卤代烃，其中R3定义如上，X表示卤素原子。

公开(公告)号：US3954729A

公开(公告)日：1976-05-04

申请号：US454619

申请日：1974-03-25

申请人： Zenichi Sato ,  Keiichiro Takagi ,  Masamichi Shimizu

发明人： Zenichi Sato ,  Keiichiro Takagi ,  Masamichi Shimizu

IPC分类号： C07C333/02 ,  C07C67/00 ,  C07C325/00 ,  C07C333/04 ,  C07D295/21 ,  C07C155/02

CPC分类号： C07D295/21

摘要： Thiolcarbamates are prepared by reacting a secondary amine having the formula ##EQU1## wherein R.sub.1 and R.sub.2 are the same or different and each represent hydrogen, lower alkyl, alkoxy, alkenyl, alkoxyalkyl, cycloalkyl, hydroxyalkyl, benzyl or phenyl or R.sub.1 and R.sub.2 combined is a nitrogen containing heterocyclic ring with carbonylsulfide to form an intermediate of an amine salt of a thiolcarbamic acid having the formula ##EQU2## wherein R.sub.1 and R.sub.2 are defined as above, in an organic solvent having the formula ##SPC1##Wherein n is 0, 1 or 2 and R' is hydrogen, halogen or a lower alkyl group which solvent is sparingly soluble or insoluble in water and which dissolves the amine salt of the thiolcarbonic acid, and then reacting the intermediate with an alkyl halide having the formulaX -- CH.sub.2 -- R.sub.3wherein X represents halogen, and R.sub.3 represents hydrogen, lower alkyl or naphthyl or phenyl which can be substituted with halogen, alkyl, alkoxy, alkylthio, cyano or nitro, to yield a thiolcarbamate having the formula ##EQU3##

摘要翻译： 硫代氨基甲酸盐通过使具有式R 1 ANGLE NH R 2的仲胺反应制备，其中R 1和R 2相同或不同，各自代表氢，低级烷基，烷氧基，烯基，烷氧基烷基，环烷基，羟基烷基，苄基或苯基或R 1和R 2组合 是具有羰硫基的含氮杂环，以形成具有式R 1，R 2，R 2，R 2，R 2，R 2和R 2如上定义的硫代氨基甲酸的胺盐的中间体，其中R 1和R 2如上定义， 具有式WHEREIN N IS 0,1或2的有机溶剂，R'是氢，卤素或低级烷基，其溶剂微溶或不溶于水，并溶解硫醇碳酸的胺盐，然后使中间体 与具有式X-CH 2 -R 3的烷基卤化物，其中X表示卤素，R 3表示氢，可被卤素，烷基，烷氧基，烷硫基，氰基o取代的低级烷基或萘基或苯基 r硝基，得到具有式R1O平行角N-C-S-CH2-R3的硫代氨基甲酸酯。 R2