公开(公告)号：US20230354784A1

公开(公告)日：2023-11-09

申请号：US18344913

申请日：2023-06-30

Applicant: Zhejiang University

Inventor： Jinming PAN ,  Li ZENG ,  Qiong LIU ,  Tao WANG ,  Jian LI ,  Zunzhong YE

IPC: A01K41/02

CPC classification number: A01K41/023

Abstract: A method for reducing the negative effect of heat acclimatization for the hatching of a poultry hatching egg is provided. A special light source is used as an ambient light to hatch the poultry hatching egg. The special light source is light-emitting diode (LED) monochromatic blue light with a light intensity of 20 lux to 50 lux and a wavelength of about 450 nm, such that the light can reduce the negative effect of heat acclimatization at a hatching stage of the poultry hatching egg. The method can reduce the levels of oxidation products such as malondialdehyde (MDA) and corticosterone in a chicken embryo during heat acclimatization at the hatching stage of the poultry hatching egg and increase the expression levels of antioxidase and heat shock protein (HSP) genes, and the special light source reduces the metabolic heat production of the chicken embryo.

公开(公告)号：US20200326343A1

公开(公告)日：2020-10-15

申请号：US16794240

申请日：2020-02-19

Applicant: Zhejiang University

Inventor： Tianhua ZHOU ,  Yi LU ,  Yuehong YANG ,  Qiong LIU ,  Yaoping HUANG ,  Shanshan XIE

IPC: G01N33/574 ,  C07K16/30

Abstract: The present disclosure discloses the Twa1 gene and its expression products and applications. This disclosure first discovers and verifies the role of the Twa1 gene and its expression product in the occurrence and development of cancer. The Twa1 gene and its expression product has the ability to promote cell proliferation, growth, migration, invasion, and tumor formation, thereby providing a diagnosis of malignant tumors. This disclosure also provides new targets and strategies for inhibiting or interfering with the occurrence and development of many malignant tumors. The present disclosure provides an expression vector containing the Twa1 gene and a transgenic cell line and host bacteria containing the expression vector.