-
公开(公告)号:US20100003712A1
公开(公告)日:2010-01-07
申请号:US12474413
申请日:2009-05-29
IPC分类号: C12Q1/02 , C07K14/715
CPC分类号: C12Q1/37 , G01N33/6869 , G01N2333/9648 , G01N2500/10
摘要: A biomarker that correlates to treatment with drugs that inhibit chymase is disclosed. This biomarker has been shown to have utility in assessing response to chymase inhibitor compounds. The immunoreactivity or levels of the biomarker is increased upon treatment with chymase inhibitor compounds, thus indicating that this biomarker is involved in chymase activity.
摘要翻译: 公开了与用抑制胃促胰酶的药物治疗相关的生物标志物。 该生物标志物已被证明可用于评估对胃促胰酶抑制剂化合物的反应。 在用糜酶抑制剂化合物治疗时,生物标志物的免疫反应性或水平增加,因此表明该生物标志物参与糜酶活性。