专利检索 ap:("eFFECTOR Therapeutics, Inc.") AND inv:"Samuel SPERRY" 第 1 页

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发明申请
Piperidine-Substituted Mnk Inhibitors and Methods Related Thereto 审中-公开

公开(公告)号：US20180228803A1

公开(公告)日：2018-08-16

申请号：US15895523

申请日：2018-02-13

申请人： eFFECTOR Therapeutics, Inc.

发明人： Justin T. ERNST , Paul A. SPRENGELER , Siegfried H. REICH , Samuel SPERRY

IPC分类号： A61K31/506 , A61P35/02 , A61P29/00

CPC分类号： A61K31/506 , A61P29/00 , A61P35/02

摘要： The present invention relates to compounds according to Formula (I): or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof wherein X1, X2, R1, R2, R3 and n are as defined herein. Also described are pharmaceutically acceptable compositions of Formula (I) compounds as well as methods for utilizing the compounds of Formula (I) and the pharmaceutically acceptable compositions of Formula (I) compounds as inhibitors of Mnk as well as therapeutics for the treatment of diseases such as cancer.