公开(公告)号：US12233110B2

公开(公告)日：2025-02-25

申请号：US18444443

申请日：2024-02-16

Applicant: i20 Therapeutics, Inc.

Inventor： Tyler Brown ,  Kelly Ibsen

IPC: A61K38/22 ,  A61K9/08 ,  A61K31/14 ,  A61K38/26 ,  A61K47/12 ,  A61K47/18 ,  A61K47/54 ,  A61K47/68 ,  C07K14/575 ,  C07K14/605 ,  C07K16/24 ,  A61K38/00

Abstract: Provided herein are compounds having the structure of Formula I, wherein the compounds comprises a therapeutic agent having the sequence of SEQ ID NO: 35, and the compounds have an anion:cation molar ratio of from about 1:1 to about 1:7, and methods of using thereof for the treatment of metabolic diseases or disorders, including type 1 diabetes, type 2 diabetes, obesity, overweight, and nonalcoholic steatohepatitis, and for reducing weight in a subject in need thereof.