专利检索 caee:"ADEN INTERNATIONAL CO.,LTD." 第 1 页

1.

发明公开
METHOD OF ISOLATION, PURIFICATION, AND CHARACTERIZATION OF HEPARIN-LIKE SUBSTANCES FROM SNAIL MUCUS (ACHATINA FULICA) AND ITS USES 审中-公开

公开(公告)号：US20240041943A1

公开(公告)日：2024-02-08

申请号：US18265655

申请日：2021-01-08

申请人： ADEN INTERNATIONAL CO.,LTD.

发明人： Prachya KONGTAWELERT

IPC分类号： A61K35/618 , A61P35/00

CPC分类号： A61K35/618 , A61P35/00

摘要： Heparin-like substances (HLS) have their structure similar with heparin, the highly sulfated glycosaminoglycan (GAGs). The polysaccharide, a product of mast cells, is isolated from animal tissues (pig intestinal mucosa, bovine lung), and owes its anticoagulant activity, activates antithrombin and proteases inhibitor. Disclosed herein are novel methods of isolation, purification and characterization of HLS from snail mucus (Achatina fulica), and its uses. This HLS can be used to develop a simple, sensitive and specific assay for its biological activities of anti-SARs-CoV-2 (COVID-19) and anti-PD-L1 on the breast cancer cell.