公开(公告)号：US20240041943A1

公开(公告)日：2024-02-08

申请号：US18265655

申请日：2021-01-08

申请人： ADEN INTERNATIONAL CO.,LTD.

发明人： Prachya KONGTAWELERT

IPC分类号： A61K35/618 ,  A61P35/00

CPC分类号： A61K35/618 ,  A61P35/00

摘要： Heparin-like substances (HLS) have their structure similar with heparin, the highly sulfated glycosaminoglycan (GAGs). The polysaccharide, a product of mast cells, is isolated from animal tissues (pig intestinal mucosa, bovine lung), and owes its anticoagulant activity, activates antithrombin and proteases inhibitor. Disclosed herein are novel methods of isolation, purification and characterization of HLS from snail mucus (Achatina fulica), and its uses. This HLS can be used to develop a simple, sensitive and specific assay for its biological activities of anti-SARs-CoV-2 (COVID-19) and anti-PD-L1 on the breast cancer cell.

公开(公告)号：US20230346869A1

公开(公告)日：2023-11-02

申请号：US18206355

申请日：2023-06-06

申请人： StellaLife, Inc.

发明人： Walter Tatch

IPC分类号： A61K36/714 ,  A61K33/28 ,  A61K35/618 ,  A61K36/28 ,  A61K36/56 ,  A61K36/68 ,  A61K36/75 ,  A61K41/00 ,  A61K45/06

CPC分类号： A61K36/714 ,  A61K33/28 ,  A61K35/618 ,  A61K36/28 ,  A61K36/56 ,  A61K36/68 ,  A61K36/75 ,  A61K41/0004 ,  A61K45/06

摘要： Methods of maintaining general oral care as well as reducing inflammation, pain, and bruising after oral surgery with a homeopathic recovery kit are disclosed.

公开(公告)号：US20230310535A1

公开(公告)日：2023-10-05

申请号：US18206349

申请日：2023-06-06

申请人： StellaLife, Inc.

发明人： Walter Tatch

IPC分类号： A61K36/714 ,  A61K35/618 ,  A61K36/28 ,  A61K36/75 ,  A61K33/28 ,  A61K36/56 ,  A61K41/00 ,  A61K45/06 ,  A61K36/68

CPC分类号： A61K36/714 ,  A61K35/618 ,  A61K36/28 ,  A61K36/75 ,  A61K33/28 ,  A61K36/56 ,  A61K41/0004 ,  A61K45/06 ,  A61K36/68

摘要： Methods of maintaining general oral care as well as reducing inflammation, pain, and bruising after oral surgery with a homeopathic recovery kit are disclosed.

公开(公告)号：US20180271818A1

公开(公告)日：2018-09-27

申请号：US15935913

申请日：2018-03-26

申请人： Solutex NA LLC

发明人： Gerhardus Lucas Bannenberg ,  Charles Nicholas Serhan ,  Fernando Moreno Egea

IPC分类号： A61K31/202 ,  A61K36/02 ,  A61K35/612 ,  A61K31/557 ,  A61K35/60 ,  A61K35/618

CPC分类号： A61K31/202 ,  A61K31/557 ,  A61K35/60 ,  A61K35/612 ,  A61K35/618 ,  A61K36/02

摘要： The present invention encompasses oils that have anti-inflammatory or resolution-stimulating activity that contain or are enriched with Specialized Proresolving Mediators (SPM) or SPM precursors, which originate from an oil obtained from organisms containing long chain omega-3 polyunsaturated fatty acids, such as fish, crustaceae, algae, and mollusks. The invention also encompasses a method for the production of these oils, and the utilization of the oils for nutritional supplements, pharmaceutical formulations, and cosmetic formulations, which can be employed for treating an inflammatory condition.

公开(公告)号：US20180055874A1

公开(公告)日：2018-03-01

申请号：US15805079

申请日：2017-11-06

申请人： James Sullivan ,  Forrest Haag ,  Lianne Maso de Moya

发明人： James Sullivan ,  Forrest Haag ,  Lianne Maso de Moya

IPC分类号： A61K31/737 ,  A61K31/56 ,  A61K9/48 ,  A61K31/232 ,  A61K31/7008 ,  A61K36/76 ,  A61K35/618 ,  A61K36/232 ,  A61K36/324 ,  A61K9/00 ,  A61K31/7034 ,  A61K31/19 ,  A61K31/202

CPC分类号： A61K31/737 ,  A61K9/0053 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4875 ,  A61K31/19 ,  A61K31/202 ,  A61K31/232 ,  A61K31/56 ,  A61K31/7008 ,  A61K31/7034 ,  A61K35/618 ,  A61K36/232 ,  A61K36/324 ,  A61K36/76 ,  A61K2300/00

摘要： The instant invention provides a method and composition for treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis, lameness, post operative arthroscopic surgery, deterioration of proper joint function including joint mobility, the reduction or inhibition of metabolic activity of chondrocytes, the activity of enzymes that degrade cartilage, said method comprising administering effective amounts of Boswellia Serrata, effective amounts of freeze dried green lipped mussle, effective amounts of white willow bark extract containing salicin, effective amounts of angelica root, effective amounts of glucosamine and salts thereof, effective amounts of chondroitin and salts thereof and effective amounts of omega 3 fatty acids.

公开(公告)号：US20170290873A1

公开(公告)日：2017-10-12

申请号：US15093786

申请日：2016-04-08

申请人： Stellalife

发明人： Walter Tatch

IPC分类号： A61K36/714 ,  A61K36/28 ,  A61K36/56 ,  A61K33/28 ,  A61K36/185 ,  A61K36/51 ,  A61K35/618 ,  A61K36/75

CPC分类号： A61K36/714 ,  A61K33/28 ,  A61K35/618 ,  A61K36/28 ,  A61K36/56 ,  A61K36/68 ,  A61K36/75 ,  A61K41/0004 ,  A61K45/06 ,  A61K2300/00

摘要： Methods of maintaining general oral care as well as reducing inflammation, pain and bruising after oral surgery with a homeopathic recovery kit are disclosed.

公开(公告)号：US20170049804A1

公开(公告)日：2017-02-23

申请号：US15345399

申请日：2016-11-07

申请人： James Sullivan ,  Forrest Haag ,  Lianne Maso de Moya

发明人： James Sullivan ,  Forrest Haag ,  Lianne Maso de Moya

IPC分类号： A61K31/737 ,  A61K36/232 ,  A61K35/618 ,  A61K36/76 ,  A61K9/48 ,  A61K31/7008 ,  A61K31/202 ,  A61K36/324 ,  A61K9/00 ,  A61K31/56 ,  A61K31/7034

CPC分类号： A61K31/737 ,  A61K9/0053 ,  A61K9/4825 ,  A61K9/4858 ,  A61K9/4875 ,  A61K31/19 ,  A61K31/202 ,  A61K31/232 ,  A61K31/56 ,  A61K31/7008 ,  A61K31/7034 ,  A61K35/618 ,  A61K36/232 ,  A61K36/324 ,  A61K36/76 ,  A61K2300/00

摘要： The instant invention provides a method and composition for treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis, lameness, post operative arthroscopic surgery, deterioration of proper joint function including joint mobility, the reduction or inhibition of metabolic activity of chondrocytes, the activity of enzymes that degrade cartilage, said method comprising administering effective amounts of Boswellia Serrata, effective amounts of freeze dried green lipped mussle, effective amounts of white willow bark extract containing salicin, effective amounts of angelica root, effective amounts of glucosamine and salts thereof, effective amounts of chondroitin and salts thereof and effective amounts of omega 3 fatty acids.

摘要翻译： 本发明提供了用于治疗或预防骨关节炎，关节积液，关节炎症和疼痛，滑膜炎，跛行，术后关节镜手术，包括关节活动性的适当关节功能恶化，软骨细胞代谢活性降低或抑制的方法和组合物， 所述方法包括施用有效量的乳香型乳杆菌，有效量的冷冻干燥绿色唇彩，有效量的含有水杨酸的白柳树皮提取物，有效量的当归根，有效量的葡糖胺及其盐 ，有效量的软骨素及其盐和有效量的ω3脂肪酸。

公开(公告)号：US09282735B2

公开(公告)日：2016-03-15

申请号：US14707650

申请日：2015-05-08

申请人： Innospec Limited ,  W. Neudorff GMBH KG

发明人： Nicholas John Dixon ,  Derek Bassett ,  Reinhard Arndt ,  Andreas Prokop ,  Diana Parker ,  Tianye Chen

IPC分类号： A01N25/00 ,  A61K35/618 ,  A01N59/26 ,  C05G3/02

CPC分类号： A01N25/008 ,  A01N25/00 ,  A01N59/26 ,  A61K35/618 ,  C05G3/02 ,  A01N37/44 ,  A01N2300/00

摘要： A molluscicidal composition, comprising: a molluscicidal activity promoting additive comprising a calcium-containing salt of ethylene disuccinic acid or calcium ions and ethylenediamine disuccinic moieties, having at least 1 mole of calcium per mole of ethylenediamine disuccinic acid; and a carrier material edible to molluscs.

摘要翻译： 一种杀软体动物组合物，其包含：杀软体动物活性促进添加剂，其包含乙二琥珀酸或钙离子的钙盐和乙二胺二琥珀酸部分，每摩尔乙二胺二琥珀酸具有至少1摩尔钙/ 和可食用于软体动物的载体材料。

公开(公告)号：US20150258181A1

公开(公告)日：2015-09-17

申请号：US14656304

申请日：2015-03-12

申请人： LivePet, LLC

发明人： Ian Mitchell ,  Ayyappan Subbiah ,  Daniel David Bensimon

IPC分类号： A61K38/48 ,  A61K31/015 ,  A61K38/07

CPC分类号： A61K38/4806 ,  A61K31/00 ,  A61K31/015 ,  A61K35/618 ,  A61K36/63 ,  A61K38/05 ,  A61K38/07 ,  A61K38/4886 ,  C12Y304/2404 ,  A61K2300/00

摘要： In some embodiments, a chemical composition may include C60, serrapeptase, or a tetrapeptide. The tetrapeptide may include ALA,GLU,ASP,GLY. In some embodiments, the chemical composition may include a dipeptide. The dipeptide may include carnosine or camatine. In some embodiments, the chemical composition may include at least one lipid. One or more components of the chemical composition may be suspended in and/or dissolved in the at least one lipid. At least one lipid may include olive oil or mussel oil. In some embodiments, a method may include administering to a subject an effective amount of a pharmaceutically acceptable formulation comprising the chemical composition. The method may include inhibiting and/or ameliorating inflammation and/or a malady associated with inflammation. In some embodiments, the subject may include a human or a nonhuman mammal. Nonhuman mammals may include equines, canines, or felines.

摘要翻译： 在一些实施方案中，化学组合物可包括C60，锯齿酶解酶或四肽。 四肽可以包括ALA，GLU，ASP，GLY。 在一些实施方案中，化学组合物可以包括二肽。 二肽可以包括肌肽或卡马汀。 在一些实施方案中，化学组合物可以包括至少一种脂质。 化学组合物的一种或多种组分可以悬浮在和/或溶解于至少一种脂质中。 至少一种脂质可以包括橄榄油或贻贝油。 在一些实施方案中，方法可以包括向受试者施用有效量的包含化学组成的药学上可接受的制剂。 该方法可以包括抑制和/或改善炎症和/或与炎症相关的疾病。 在一些实施方案中，受试者可以包括人或非人类哺乳动物。 非人类哺乳动物可能包括马，犬或猫科动物。

公开(公告)号：US20150237850A1

公开(公告)日：2015-08-27

申请号：US14707650

申请日：2015-05-08

申请人： Nicholas John Dixon ,  Derek Bassett ,  Reinhard Arndt ,  Andreas Prokop ,  Diana Parker ,  Tianye Chen

发明人： Nicholas John Dixon ,  Derek Bassett ,  Reinhard Arndt ,  Andreas Prokop ,  Diana Parker ,  Tianye Chen

IPC分类号： A01N25/00 ,  A01N59/26

CPC分类号： A01N25/008 ,  A01N25/00 ,  A01N59/26 ,  A61K35/618 ,  C05G3/02 ,  A01N37/44 ,  A01N2300/00

摘要： A molluscicidal composition, comprising: a molluscicidal activity promoting additive comprising a calcium-containing salt of ethylene disuccinic acid or calcium ions and ethylenediamine disuccinic moieties, having at least 1 mole of calcium per mole of ethylenediamine disuccinic acid; and a carrier material edible to molluscs.

摘要翻译： 一种杀软体动物组合物，其包含：杀软体动物活性促进添加剂，其包含乙二琥珀酸或钙离子的钙盐和乙二胺二琥珀酸部分，每摩尔乙二胺二琥珀酸具有至少1摩尔钙/ 和可食用于软体动物的载体材料。