公开(公告)号：US5756469A

公开(公告)日：1998-05-26

申请号：US686820

申请日：1996-07-26

Applicant: Paxton K. Beale

Inventor： Paxton K. Beale

IPC: A61K31/19 ,  A61K45/06 ,  A61K31/70 ,  A61K31/715 ,  A61K31/685

CPC classification number: A61K31/19 ,  A61K45/06

Abstract: The present invention is based, in part, upon the discovery that the use of pyruvate in combination with a cortisol blocker, such as phosphatidylserine, produces a synergistic effect in increasing lean body mass or muscle tissue, decreasing fat deposition, increasing endurance and athletic performance of a mammal consuming same. The invention also relates to a method of treating the catabolic effects of diseases such as cancer and AIDS by the administration of pyruvate and a cortisol blocker. The present invention also discloses a synergistic composition comprising pyruvate and a cortisol blocker. More specifically, the present invention relates to a composition which comprises pyruvate and/or derivatives of pyruvate and phosphatidylserine.

Abstract translation: 本发明部分地基于以下发现：丙酮酸与皮质醇阻滞剂（例如磷脂酰丝氨酸）组合的使用在增加瘦体重或肌肉组织，减少脂肪沉积，增加耐力和运动表现方面产生协同作用 消耗它的哺乳动物。 本发明还涉及通过施用丙酮酸和皮质醇阻滞剂来治疗诸如癌症和AIDS的疾病的分解代谢作用的方法。 本发明还公开了包含丙酮酸和皮质醇阻滞剂的协同组合物。 更具体地，本发明涉及包含丙酮酸和/或丙酮酸和磷脂酰丝氨酸的衍生物的组合物。

公开(公告)号：US6008252A

公开(公告)日：1999-12-28

申请号：US71008

申请日：1998-05-01

Applicant: Paxton K. Beale

Inventor： Paxton K. Beale

IPC: A61K31/19 ,  A61K31/195 ,  A01N37/12

CPC classification number: A61K31/19 ,  A61K31/195

Abstract: The present invention is based in part upon the discovery that the use of pyruvate in enteral formulations, in combination with anaerobic exercise produces a synergistic effect in increasing the amount of lean body mass or muscle tissue in a mammal. The present invention relates generally to a composition for enhancing the protein concentration or muscle mass of a mammal and a method for enhancing the protein concentration or muscle mass in a mammal. More specifically, the present invention relates to the consumption of a composition which comprises calcium pyruvate and potassium pyruvate and derivatives of pyruvate such as pyruvyl-creatine and anaerobic exercise to enhance muscle mass. The method of the present invention comprises administering to a mammal in need of enhancing its protein concentration or muscle mass, a composition comprising pyruvate and the subjecting of a mammal to anaerobic exercise. The pyruvate composition can take the form of powders, liquids, pills, capsules, tablets, food additives, candies or confections.

Abstract translation: 本发明部分地基于以下发现：肠内制剂中的丙酮酸盐与无氧运动的组合在增加哺乳动物中瘦体重或肌肉组织的量方面产生协同效应。 本发明一般涉及用于增强哺乳动物的蛋白质浓度或肌肉质量的组合物以及用于增强哺乳动物蛋白质浓度或肌肉质量的方法。 更具体地，本发明涉及包含丙酮酸钙和丙酮酸钾以及丙酮酸衍生物如丙酮酸和无氧运动的组合物的消耗，以增强肌肉质量。 本发明的方法包括向需要增强其蛋白质浓度或肌肉质量的哺乳动物施用包含丙酮酸盐的组合物和使哺乳动物进行无氧运动。 丙酮酸组合物可以采取粉末，液体，丸剂，胶囊，片剂，食品添加剂，糖果或糖果的形式。

公开(公告)号：US5889040A

公开(公告)日：1999-03-30

申请号：US951547

申请日：1997-10-16

Applicant: Paxton K. Beale ,  Donald O. Nickey

Inventor： Paxton K. Beale ,  Donald O. Nickey

IPC: A61K31/19 ,  A61K31/195 ,  A61K31/415

CPC classification number: A61K31/19 ,  A61K31/195 ,  A61K31/415

Abstract: The present invention is based in part upon the discovery that the use of pyruvate in enteral formulations, in combination with an anabolic protein composition, produces a synergistic effect in increasing the lean body mass or muscle tissue of a mammal consuming same. The present invention also provides a method for enhanced endurance of athletes.The present invention relates generally to a composition for enhancing the protein concentration or muscle mass of a mammal and a method for enhancing the protein concentration or muscle mass in a mammal. More specifically, the present invention relates to a composition which comprises pyruvate and/or derivatives of pyruvate and an anabolic protein composition. The method of the present invention comprises administering to a mammal in need of enhancing its protein concentration or muscle mass, a composition comprising pyruvate and an anabolic protein composition.The pyruvate/anabolic protein composition can take the form of powders, liquids, pills, capsules, tablets, food additives, candies or confections.

Abstract translation: 本发明部分地基于以下发现：肠内制剂中的丙酮酸与合成代谢蛋白质组合物的组合在增加消耗其的哺乳动物的瘦体重或肌肉组织中产生协同效应。 本发明还提供一种增强运动员耐力的方法。 本发明一般涉及用于增强哺乳动物的蛋白质浓度或肌肉质量的组合物以及用于增强哺乳动物蛋白质浓度或肌肉质量的方法。 更具体地，本发明涉及包含丙酮酸和/或丙酮酸衍生物和合成代谢蛋白质组合物的组合物。 本发明的方法包括向需要增强其蛋白质浓度或肌肉质量的哺乳动物施用包含丙酮酸和合成代谢蛋白质组合物的组合物。 丙酮酸/合成代谢蛋白质组合物可以采取粉末，液体，丸剂，胶囊，片剂，食品添加剂，糖果或糖果的形式。

公开(公告)号：US5716926A

公开(公告)日：1998-02-10

申请号：US686819

申请日：1996-07-26

Applicant: Paxton K. Beale ,  Donald O. Nickey

Inventor： Paxton K. Beale ,  Donald O. Nickey

IPC: A61K31/19 ,  A61K31/195 ,  A61K31/415 ,  A23L1/305 ,  A61K31/22 ,  A61K38/01

CPC classification number: A61K31/19 ,  A61K31/195 ,  A61K31/415

Abstract: The present invention is based in part upon the discovery that the use of pyruvate in enteral formulations, in combination with an anabolic protein composition, produces a synergistic effect in increasing the lean body mass or muscle tissue of a mammal consuming same. The present invention also provides a method for enhanced endurance of athletes. The present invention relates generally to a composition for enhancing the protein concentration or muscle mass of a mammal and a method for enhancing the protein concentration or muscle mass in a mammal. More specifically, the present invention relates to a composition which comprises pyruvate and/or derivatives of pyruvate and an anabolic protein composition. The method of the present invention comprises administering to a mammal in need of enhancing its protein concentration or muscle mass, a composition comprising pyruvate and an anabolic protein composition. The pyruvate/anabolic protein composition can take the form of powders, liquids, pills, capsules, tablets, food additives, candies or confections.

Abstract translation: 本发明部分地基于以下发现：肠内制剂中的丙酮酸与合成代谢蛋白质组合物的组合在增加消耗其的哺乳动物的瘦体重或肌肉组织中产生协同效应。 本发明还提供一种增强运动员耐力的方法。 本发明一般涉及用于增强哺乳动物的蛋白质浓度或肌肉质量的组合物以及用于增强哺乳动物蛋白质浓度或肌肉质量的方法。 更具体地，本发明涉及包含丙酮酸和/或丙酮酸衍生物和合成代谢蛋白质组合物的组合物。 本发明的方法包括向需要增强其蛋白质浓度或肌肉质量的哺乳动物施用包含丙酮酸和合成代谢蛋白质组合物的组合物。 丙酮酸/合成代谢蛋白质组合物可以采取粉末，液体，丸剂，胶囊，片剂，食品添加剂，糖果或糖果的形式。

公开(公告)号：US5919767A

公开(公告)日：1999-07-06

申请号：US27522

申请日：1998-02-23

Applicant: Paxton K. Beale

Inventor： Paxton K. Beale

IPC: A61K31/19 ,  A61K45/06 ,  A61K31/70 ,  A61K31/715 ,  A61K31/685

CPC classification number: A61K31/19 ,  A61K45/06

Abstract: The present invention is based, in part, upon the discovery that the use of pyruvate in combination with a cortisol blocker, such as phosphatidylserine, produces a synergistic effect in increasing lean body mass or muscle tissue, decreasing fat deposition, increasing endurance and athletic performance of a mammal consuming same. The invention also relates to a method of treating the catabolic effects of diseases such as cancer and AIDS by the administration of pyruvate and a cortisol blocker.The present invention also discloses a synergistic composition comprising pyruvate and a cortisol blocker. More specifically, the present invention relates to a composition which comprises pyruvate and/or derivatives of pyruvate and phosphatidylserine.

Abstract translation: 本发明部分地基于以下发现：丙酮酸与皮质醇阻滞剂（例如磷脂酰丝氨酸）组合的使用在增加瘦体重或肌肉组织，减少脂肪沉积，增加耐力和运动表现方面产生协同作用 消耗它的哺乳动物。 本发明还涉及通过施用丙酮酸和皮质醇阻滞剂来治疗诸如癌症和AIDS的疾病的分解代谢作用的方法。 本发明还公开了包含丙酮酸和皮质醇阻滞剂的协同组合物。 更具体地，本发明涉及包含丙酮酸和/或丙酮酸和磷脂酰丝氨酸的衍生物的组合物。

公开(公告)号：US4743009A

公开(公告)日：1988-05-10

申请号：US933102

申请日：1986-11-20

Applicant: Paxton K. Beale

Inventor： Paxton K. Beale

IPC: A63B22/02 ,  A63B23/02 ,  A63B23/06 ,  A61H1/02

CPC classification number: A63B22/02 ,  A63B69/0057 ,  A63B2208/02 ,  A63B2208/0261 ,  A63B23/0233 ,  Y10S482/901

Abstract: Apparatus for training a person to walk with proper or improved pelvic posture. The apparatus includes a treadmill and mechanical means for controllably imposing a preselected pelvic posture on a person on the treadmill. A control circuit coupled to the mechanical means causes the mechanical means to impose a preselected pelvic posture on a person on the treadmill for a preselected training time period, and then releases the person's pelvis. Using this apparatus, a person walking on the treadmill can learn to walk with proper pelvic posture by first walking during a training time period with a preselected pelvic posture, and by thereafter walking without being restrained by the mechanical means while trying to maintain the pelvic posture position learned during the training time period.

Abstract translation: 用于训练人以适当或改善的骨盆姿势行走的装置。 该装置包括跑步机和机械装置，用于可控地将预选的盆腔姿势施加在跑步机上的人身上。 耦合到机械装置的控制电路使得机械装置对预选的训练时间段在跑步机上的人施加预选的盆腔姿势，然后释放人的骨盆。 使用该装置，在跑步机上行走的人可以通过在具有预选的盆腔姿势的训练时间段期间首先行走，并且随后在不受机械装置的限制的情况下行走时可以通过适当的盆腔姿势行走，同时尝试维持骨盆姿势 在训练期间学习的职位。