REGULATORY IMMUNE CELLS WITH ENHANCED TARGETED CELL DEATH EFFECT
    1.
    发明申请
    REGULATORY IMMUNE CELLS WITH ENHANCED TARGETED CELL DEATH EFFECT 有权
    具有增强的靶向细胞死亡效应的调节性免疫细胞

    公开(公告)号:US20130129771A1

    公开(公告)日:2013-05-23

    申请号:US13811374

    申请日:2011-07-21

    IPC分类号: C12N5/0783 A61K35/14

    摘要: An isolated immune regulatory cell having an exogenous cell death-inducing moiety attached to a surface thereof is disclosed herein. Additionally, a molecule comprising a cell death-inducing moiety heterologously attached to an immune regulatory cell-specific binding moiety is disclosed herein. Methods of generating and using same as well as pharmaceutical compositions comprising same are also disclosed.

    摘要翻译: 本文公开了具有连接到其表面的外源性细胞死亡诱导部分的分离的免疫调节细胞。 此外,本文公开了包含异源连接到免疫调节细胞特异性结合部分的细胞死亡诱导部分的分子。 还公开了产生和使用它们的方法以及包含其的药物组合物。

    Methods of selecting stem cells and uses thereof
    2.
    发明授权
    Methods of selecting stem cells and uses thereof 有权
    选择干细胞的方法及其用途

    公开(公告)号:US08435786B2

    公开(公告)日:2013-05-07

    申请号:US12227865

    申请日:2007-05-31

    申请人: Nadir Askenasy

    发明人: Nadir Askenasy

    IPC分类号: C12N5/00

    摘要: A method of selecting stem cells from heterogeneous population of cells is disclosed. The method comprises contacting the population of cells with an apoptosis inducing agent under conditions which are apoptotic to non-stem cells and non-apoptotic to stem cells, thereby selecting the stem cells from the heterogeneous population of cells. The selected stem cells may then be used for a variety of applications including transportation and differentiation.

    摘要翻译: 公开了从异种细胞群体中选择干细胞的方法。 该方法包括在凋亡至非干细胞和非细胞凋亡至干细胞的条件下使细胞群与凋亡诱导剂接触,从而从异源细胞群中选择干细胞。 所选择的干细胞然后可以用于各种应用,包括运输和分化。