公开(公告)号：US5075338A

公开(公告)日：1991-12-24

申请号：US420058

申请日：1989-10-11

申请人： Jozsef Knoll ,  Antal Simay ,  Eva Szinnyei ,  Eva Somfai ,  Zoltan Torok ,  Karoly Mozsolits ,  Janos Bergmann

发明人： Jozsef Knoll ,  Antal Simay ,  Eva Szinnyei ,  Eva Somfai ,  Zoltan Torok ,  Karoly Mozsolits ,  Janos Bergmann

IPC分类号： C07C211/27 ,  A61K31/135 ,  A61K31/137 ,  A61P25/24

CPC分类号： A61K31/135

摘要： A method of treating a learning deficiency is disclosed wherein a patient in need of stimulating learning ability is treated with a therapeutically effective amount of a compound of the Formula (I) ##STR1## wherein R.sup.1 is C.sub.1 to C.sub.8 straight or branched chain alkyl, C.sub.7 to C.sub.10 phenylalkyl, phenyl, or C.sub.3 to C.sub.8 cycloalkyl; andR.sup.2 is C.sub.1 to C.sub.8 straight or branched chain alkyl, unsubstituted or substituted by halogen, hydroxy, C.sub.1 to C.sub.4 alkoxy or by 1 or 2 phenyl groups; or is C.sub.3 to C.sub.8 cycloalkyl;with the proviso that R.sup.1 and R.sup.2 together contain at least 3 carbon atoms; or a pharmaceutically acceptable salt thereof.

摘要翻译： 公开了一种治疗学习缺陷的方法，其中需要刺激学习能力的患者用治疗有效量的式（I）化合物（I）治疗，其中R1为C1至C8直链或支链 烷基，C7至C10苯基烷基，苯基或C3至C8环烷基; R2为C1至C8直链或支链烷基，未取代或被卤素，羟基，C1至C4烷氧基取代或被1或2个苯基取代; 或为C3至C8环烷基; 条件是R1和R2一起含有至少3个碳原子; 或其药学上可接受的盐。