-
公开(公告)号：US12075907B2
公开(公告)日：2024-09-03
申请号：US17417088
申请日：2019-12-26
申请人： Lion Corporation
发明人： Yuya Kimoto
CPC分类号： A46B15/004 , A46B5/02 , A46B2200/1066
摘要： An object of the present invention is to provide a toothbrush that enables an appropriate brushing pressure to be more reliably recognized. A head portion (10) provided on a tip end side in a long axis direction and having a bristle tufting surface (11), a grip portion (30) disposed on a rear end side from the head portion, and a neck portion (20) disposed between the bristle tufting surface and the grip portion are provided. A sound generation portion (70) that generates a click sound due to deformation when an external force in a first direction orthogonal to the bristle tufting surface exceeds a threshold value is provided on a rear end side from the bristle tufting surface.
-
公开(公告)号：US11957506B2
公开(公告)日：2024-04-16
申请号：US16970702
申请日：2019-02-26
申请人： LION CORPORATION
CPC分类号： A61B8/0858 , A61B8/12 , A61C19/04
摘要： Provided is a testing method for determining an oral indicator by which an oral indicator can be determined. The testing method for determining an oral indicator includes an image acquisition step of acquiring an ultrasonic image of an inside of an attached gingiva of a subject, using a measurement probe, an average brightness acquisition step of acquiring average brightness of the ultrasonic image, and an indicator determination step of determining an oral indicator of the subject by referring to the average brightness and a reference of an oral indicator.
-
公开(公告)号：US20220071382A1
公开(公告)日：2022-03-10
申请号：US17417088
申请日：2019-12-26
申请人： Lion Corporation
发明人： Yuya KIMOTO
摘要： An object of the present invention is to provide a toothbrush that enables an appropriate brushing pressure to be more reliably recognized. A head portion (10) provided on a tip end side in a long axis direction and having a bristle tufting surface (11), a grip portion (30) disposed on a rear end side from the head portion, and a neck portion (20) disposed between the bristle tufting surface and the grip portion are provided. A sound generation portion (70) that generates a click sound due to deformation when an external force in a first direction orthogonal to the bristle tufting surface exceeds a threshold value is provided on a rear end side from the bristle tufting surface.
-
公开(公告)号：US20220015531A1
公开(公告)日：2022-01-20
申请号：US17312384
申请日：2019-12-26
申请人： Lion Corporation
发明人： Reona NODA
摘要： A toothbrush enables an appropriate brushing pressure and includes a sensing portion for sensing that an external force in a first direction orthogonal to the bristle tufting surface exceeds a predetermined value on a rear end side from the bristle tufting surface. The sensing portion changes a relationship between a displacement amount of the head portion when a load is applied to the head portion and a repulsive force generated according to the displacement amount from an increase to a decrease in the repulsive force at a first threshold value. The first threshold value relates to an increase in the displacement amount, and stops the decrease in the repulsive force at a second threshold value. The second threshold value relates to when the displacement amount is larger than the first threshold value.
-
公开(公告)号：US11013310B2
公开(公告)日：2021-05-25
申请号：US16344336
申请日：2017-10-25
申请人： Lion Corporation
摘要： A toothbrush capable of inhibiting damage of an oral cavity of a user that includes: a head section that has a bristle implanting surface on a front end side; a handle section that is disposed on a rear end side from the head section and has a handle section main body; and a neck section that is disposed between the bristle implanting surface and the handle section. The toothbrush has a deforming portion that is located on the rear end side from the bristle implanting surface and is deformed, while stress characteristics associated with bending due to an external force acting on the head section are in a plane stress condition.
-
公开(公告)号：US09982222B2
公开(公告)日：2018-05-29
申请号：US14896635
申请日：2014-06-12
申请人： LION CORPORATION
发明人： Makoto Makino , Atsushi Tsuda , Takuya Tsutsui
摘要： A detergent composition containing an α-sulfo fatty acid alkyl ester salt and a fragrance composition, wherein the amount of the α-sulfo fatty acid alkyl ester salt is from 1 to 30% by mass relative to the total mass of the detergent composition, the fragrance composition contains a fragrance (A) described below, and the amount of the fragrance (A) is from 0.07 to 0.5% by mass relative to the total mass of the detergent composition. Fragrance (A): a fragrance composed of at least one fragrance component selected from the group consisting of dihydromyrcenol, isobornyl acetate, α-hexyl cinnamic aldehyde, lilial, tetrahydrolinalool, amyl salicylate, verdox, vertenex, tricyclodecenyl acetate, tricyclodecenyl propionate, Iso E Super and habanolide.
-
公开(公告)号：US09970946B2
公开(公告)日：2018-05-15
申请号：US14438479
申请日：2013-12-10
申请人： LION CORPORATION
发明人： Chiyoko Uchiyama , Kei Kurita
CPC分类号： G01N33/6893 , C07K14/47 , G01N33/68 , G01N2333/47 , G01N2333/8139 , G01N2800/042 , G01N2800/50
摘要： The object of the present invention is to provide a marker substance capable of determining a risk of hyperglycemia in vivo with high accuracy. The present invention provides the following: a marker peptide for determining the risk of hyperglycemia; an antibody or an aptamer bound to the marker peptide for determining the risk of hyperglycemia; a microarray wherein the antibody or the aptamer to be bound to the marker peptide for determining the risk of hyperglycemia has been immobilized onto a carrier; a method of determining the risk of hyperglycemia wherein an amount or the presence/absence of the marker peptide for determining the risk of hyperglycemia is measured in a biological sample collected from a subject; and a kit for determining the risk of hyperglycemia comprising the antibody or the aptamer, or the microarray.
-
公开(公告)号：US20150285821A1
公开(公告)日：2015-10-08
申请号：US14438479
申请日：2013-12-10
申请人： LION CORPORATION
发明人： Chiyoko Uchiyama , Kei Kurita
CPC分类号： G01N33/6893 , C07K14/47 , G01N33/68 , G01N2333/47 , G01N2333/8139 , G01N2800/042 , G01N2800/50
摘要： The object of the present invention is to provide a marker substance capable of determining a risk of hyperglycemia in vivo with high accuracy. The present invention provides the following: a marker peptide for determining the risk of hyperglycemia; an antibody or an aptamer bound to the marker peptide for determining the risk of hyperglycemia; a microarray wherein the antibody or the aptamer to be bound to the marker peptide for determining the risk of hyperglycemia has been immobilized onto a carrier; a method of determining the risk of hyperglycemia wherein an amount or the presence/absence of the marker peptide for determining the risk of hyperglycemia is measured in a biological sample collected from a subject; and a kit for determining the risk of hyperglycemia comprising the antibody or the aptamer, or the microarray.
摘要翻译： 本发明的目的是提供能够以高精度确定体内高血糖风险的标记物质。 本发明提供以下内容：用于确定高血糖风险的标记肽; 与标记肽结合的抗体或适配体，用于确定高血糖风险; 一种微阵列，其中待结合标记肽的抗体或适配体用于确定高血糖风险已被固定在载体上; 确定高血糖风险的方法，其中在从受试者收集的生物样品中测量用于确定高血糖风险的标记肽的量或存在/不存在; 以及用于确定包含抗体或适体或微阵列的高血糖风险的试剂盒。
-
公开(公告)号：US09119827B2
公开(公告)日：2015-09-01
申请号：US13381604
申请日：2010-06-29
申请人： Akito Odaka , Chieko Inoue , Manabu Hattori , Nobuhito Tabuchi
发明人： Akito Odaka , Chieko Inoue , Manabu Hattori , Nobuhito Tabuchi
IPC分类号： A61K9/00 , A61K47/44 , A61K31/74 , A61K31/203 , A61K31/20 , A61K31/22 , A61K31/23 , A61K31/232
CPC分类号： A61K31/203 , A61K9/0048 , A61K31/20 , A61K31/22 , A61K31/23 , A61K31/232 , A61K47/44
摘要： Disclosed is an ophthalmic composition which is characterized by containing (A) a vitamin A, (B) a polyoxyethylene polyoxypropylene glycol, and (C) an oil component that is selected from the group consisting of castor oil, soybean oil, sesame oil, peanut oil, olive oil, almond oil, wheat germ oil, corn oil, rapeseed oil, sunflower oil, purified lanolin and gel hydrocarbon.
摘要翻译： 本发明提供一种眼用组合物，其特征在于含有（A）维生素A，（B）聚氧乙烯聚氧丙烯二醇，（C）选自蓖麻油，大豆油，芝麻油，花生中的油成分 油，橄榄油，杏仁油，小麦胚芽油，玉米油，菜籽油，向日葵油，纯化羊毛脂和凝胶碳氢化合物。
-
10.发明授权Disinfectant composition for hard articles, and method for disinfecting of surface of hard article 有权用于硬制品的消毒剂组合物和用于消耗硬物品表面的方法公开(公告)号：US08951573B2
公开(公告)日：2015-02-10
申请号：US13698775
申请日：2011-04-18
申请人： Tomonari Suekuni , Takayasu Kubozono , Kodo Horie , Hiromu Sekioda , Tsuyoshi Miyakoshi , Yumi Kurogi
发明人： Tomonari Suekuni , Takayasu Kubozono , Kodo Horie , Hiromu Sekioda , Tsuyoshi Miyakoshi , Yumi Kurogi
IPC分类号： A01N59/20 , C11D7/18 , C11D7/10 , A01N25/22 , C11D1/722 , C11D3/04 , C11D3/33 , C11D3/48 , C11D17/06 , A01N59/00 , C11D3/39
CPC分类号： A01N25/22 , A01N59/00 , A01N59/20 , C11D1/722 , C11D3/046 , C11D3/33 , C11D3/3905 , C11D3/3937 , C11D3/3947 , C11D3/48 , C11D7/10 , C11D17/06 , A01N25/30 , A01N37/44 , A01N2300/00 , A01N25/12
摘要： Disclosed are a two-agent type disinfectant composition for hard articles, which includes a first agent containing a powder mixture (A) and a second agent containing an aqueous hydrogen peroxide solution (B-1), the powder mixture (A) containing an alkali metal salt (A-1) exhibiting basicity when the salt is in the form of an aqueous solution, a water-soluble copper salt (A-2), a compound (A-3) represented by the following formula (1), and a nonionic surfactant (A-4) represented by the following formula (2), and in which the molar ratio of the water-soluble copper salt (A-2) and the compound (A-3) represented by the mixing amount of (A-3)/mixing amount of (A-2) is 3.0 to 20; and a single-agent type disinfectant composition for hard articles, which includes the components (A-1) to (A-4), and an inorganic peroxide (B-2) that releases hydrogen peroxide in water, and in which the molar ratio of the water-soluble copper salt (A-2) and the compound (A-3) represented by the mixing amount of (A-3)/mixing amount of (A-2) is 3.0 to 20. Disinfectant compositions for hard articles which have high disinfecting power against the surfaces of hard articles, have satisfactory stability of hydrogen peroxide in water, and have low foaming tendency, and a method for disinfecting the surface of a hard article by using the disinfectant composition for hard articles, can be provided.
摘要翻译： 公开了一种用于硬制品的双剂型消毒剂组合物，其包括含有粉末混合物（A）的第一试剂和含有过氧化氢水溶液（B-1）的第二试剂，含有碱的粉末混合物（A） 当盐为水溶液形式时具有碱性的金属盐（A-1），水溶性铜盐（A-2），下式（1）表示的化合物（A-3））和 由下式（2）表示的非离子型表面活性剂（A-4），其中由水溶性铜盐（A-2）和化合物（A-3）的混合量 A-3）/（A-2）的混合量为3.0〜20; 和包含组分（A-1）至（A-4）和在水中释放过氧化氢的无机过氧化物（B-2）的硬质制品的单剂型消毒剂组合物，其中摩尔比 由（A-3）的混合量/（A-2）的混合量表示的水溶性铜盐（A-2）和化合物（A-3）的摩尔数为3.0〜20的硬质物的消毒剂组合物 可以提供对硬质物品的表面具有高消毒能力，具有令人满意的过氧化氢在水中的稳定性，发泡性低的现象，通过使用硬质物品的消毒剂组合物对硬质物品的表面进行消毒的方法 。
-
-
-
-
-
-
-
-
-
搜索结果
326 条记录 (耗时 0.028 秒)
