公开(公告)号：US4407844A

公开(公告)日：1983-10-04

申请号：US304100

申请日：1981-09-21

申请人： Guido W. Melliger

发明人： Guido W. Melliger

IPC分类号： A61J3/00 ,  B01J2/00 ,  A01N25/10

CPC分类号： A61J3/005 ,  B01J2/006 ,  A61J2200/74 ,  A61J2205/20

摘要： This invention provides an apparatus and process for automatically coating solid pharmaceutical dosage forms, e.g., tablets. The apparatus comprises a coating pan, having a rotating means, e.g., motor and a weighing means, e.g., scales in combination with the pan and motor. A process controller is in electronic communication with both the pan motor and scales, for controlling the pan rotation and monitoring the weight of the coating pan contents. There is also provided a plurality of material containing reservoirs having conduit means communicating with the interior of the pan. The material containing reservoirs may also have weighing means, e.g., scales in combination with the reservoirs, which are also in electronic communication with the process controller. These reservoirs may contain a water supply, a coating syrup supply, color suspension supply, and polishing ingredients for use in coating the tablets. The process controller is pre-programmed to dispense the various coating ingredients in a precise sequence, while monitoring the coating weight of the tablets, whereby the entire coating process is automatically effectuated in one continuous operation.

摘要翻译： 本发明提供了一种用于自动涂覆固体药物剂型例如片剂的装置和方法。 该设备包括涂覆盘，其具有旋转装置，例如马达和称重装置，例如与盘和马达组合的秤。 过程控制器与锅式电动机和秤两者进行电子通信，用于控制盘旋转并监测涂布盘内容物的重量。 还提供了多个含有储存器的材料，其具有与盘的内部连通的管道装置。 含有储存器的材料还可以具有称重装置，例如与储存器组合的秤，其也与过程控制器电子通信。 这些储存器可以包含用于涂布片剂的供水，涂料糖浆供应，颜色悬浮液供应和抛光成分。 过程控制器被预编程为以精确的顺​​序分配各种涂层成分，同时监测片剂的涂层重量，由此整个涂布过程在一个连续的操作中自动实现。

公开(公告)号：US4617872A

公开(公告)日：1986-10-21

申请号：US762577

申请日：1985-08-05

申请人： Guido W. Melliger

发明人： Guido W. Melliger

IPC分类号： A61J3/00 ,  B01J2/00 ,  G05B19/04 ,  A23G3/20

CPC分类号： G05B19/04 ,  A61J3/005 ,  B01J2/006 ,  A61J2200/74 ,  A61J2205/20

摘要： This invention provides an apparatus and process for automatically coating solid pharmaceutical dosage forms, e.g., tablets. The apparatus comprises a coating pan, having a rotating means, e.g., motor and a weighing means, e.g., scales in combination with the pan and motor. A process controller is in electronic communication with both the pan motor and scales, for controlling the pan rotation and monitoring the weight of the coating pan contents. There is also provided a plurality of material containing reservoirs having conduit means communicating with the interior of the pan. The material containing reservoirs may also have weighing means, e.g., scales in combination with the reservoirs, which are also in electronic communication with the process controller. These reservoirs may contain a water supply, a coating syrup supply, color suspension supply, and polishing ingredients for use in coating the tablets. The process controller is pre-programmed to dispense the various coating ingredients in a precise sequence, while monitoring the coating weight of the tablets, whereby the entire coating process is automatically effectuated in one continuous operation.

摘要翻译： 本发明提供了一种用于自动涂覆固体药物剂型例如片剂的装置和方法。 该设备包括涂覆盘，其具有旋转装置，例如马达和称重装置，例如与盘和马达组合的秤。 过程控制器与锅式电动机和秤两者进行电子通信，用于控制盘旋转并监测涂布盘内容物的重量。 还提供了多个含有储存器的材料，其具有与盘的内部连通的管道装置。 含有储存器的材料还可以具有称重装置，例如与储存器组合的秤，其也与过程控制器电子通信。 这些储存器可以包含用于涂布片剂的供水，涂料糖浆供应，颜色悬浮液供应和抛光成分。 过程控制器被预编程为以精确的顺​​序分配各种涂层成分，同时监测片剂的涂层重量，由此整个涂布过程在一个连续的操作中自动实现。

公开(公告)号：US4310562A

公开(公告)日：1982-01-12

申请号：US140469

申请日：1980-04-17

申请人： Guido W. Melliger

发明人： Guido W. Melliger

IPC分类号： A61J3/00 ,  B01J2/00 ,  B44D1/14

CPC分类号： B01J2/006 ,  A61J3/005 ,  A61J2200/74 ,  A61J2205/20

摘要： This invention provides an apparatus and process for automatically coating solid pharmaceutical dosage forms, e.g., tablets. The apparatus comprises a coating pan, having a rotating means, e.g., motor and a weighing means, e.g., scales in combination with the pan and motor. A process controller is in electronic communication with both the pan motor and scales, for controlling the pan rotation and monitoring the weight of the coating pan contents. There is also provided a plurality of material containing reservoirs having conduit means communicating with the interior of the pan. The material containing reservoirs may also have weighing means, e.g., scales in combination with the reservoirs, which are also in electronic communication with the process controller. These reservoirs may contain a water supply, a coating syrup supply, color suspension supply, and polishing ingredients for use in coating the tablets. The process controller is pre-programmed to dispense the various coating ingredients in a precise sequence, while monitoring the coating weight of the tablets, whereby the entire coating process is automatically effectuated in one continuous operation.

公开(公告)号：US4133290A

公开(公告)日：1979-01-09

申请号：US777468

申请日：1977-03-14

申请人： Guido W. Melliger

发明人： Guido W. Melliger

IPC分类号： A61J3/06 ,  A61J3/00 ,  B01J2/00 ,  G05B19/04 ,  B05C3/08 ,  B05C11/02

CPC分类号： A61J3/005 ,  B01J2/006 ,  G05B19/04 ,  A61J2200/74 ,  A61J2205/20

摘要： This invention provides an apparatus and process for automatically coating solid pharmaceutical dosage forms, e.g., tablets. The apparatus comprises a coating pan, having a rotating means, e.g., motor and a weighing means, e.g., scales in combination with the pan and motor. A process controller is in electronic communication with both the pan motor and scales, for controlling the pan rotation and monitoring the weight of the coating pan contents. There is also provided a plurality of material containing reservoirs having conduit means communicating with the interior of the pan. The material containing reservoirs may also have weighing means, e.g, scales in combination with the reservoirs, which are also in electronic communication with the process controller. These reservoirs may contain a water supply, a coating syrup supply, color suspension supply, and polishing ingredients for use in coating the tablets. The process controller is pre-programmed to dispense the various coating ingredients in a precise sequence, while monitoring the coating weight of the tablets, whereby the entire coating process is automatically effectuated in one continuous operation.

摘要翻译： 本发明提供了一种用于自动涂覆固体药物剂型例如片剂的装置和方法。 该设备包括涂覆盘，其具有旋转装置，例如马达和称重装置，例如与盘和马达组合的秤。 过程控制器与锅式电动机和秤两者进行电子通信，用于控制盘旋转并监测涂布盘内容物的重量。 还提供了多个含有储存器的材料，其具有与盘的内部连通的管道装置。 含有储存器的材料还可以具有称重装置，例如与储存器组合的秤，其也与过程控制器电子通信。 这些储存器可以包含用于涂布片剂的供水，涂料糖浆供应，颜色悬浮液供应和抛光成分。 过程控制器被预编程为以精确的顺​​序分配各种涂层成分，同时监测片剂的涂层重量，由此整个涂布过程在一个连续的操作中自动实现。