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公开(公告)号：US11583440B2
公开(公告)日：2023-02-21
申请号：US16650465
申请日：2018-09-26
申请人： Pixium Vision SA
发明人： Elodie Bouillet , Martin Deterre , Yves Ruffieux , Hans Bernhard
摘要： The present invention relates to a tip for use with delivery devices, particularly for use in implanting retinal implants into the retinal space of an eye. The tip includes a flexible envelope and an internal sliding member. Further, the invention relates to an inserter attachment and a delivery device including said tip.
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2.发明授权Device with flexible multilayer system for contacting or electrostimulation of living tissue cells or nerves 有权具有用于接触或电刺激活组织细胞或神经的柔性多层系统的装置公开(公告)号：US08918186B2
公开(公告)日：2014-12-23
申请号：US12280123
申请日：2007-01-26
申请人： Hans-Jürgen Tiedtke
发明人： Hans-Jürgen Tiedtke
CPC分类号： A61N1/05 , A61N1/0541 , A61N1/0543 , A61N1/40
摘要： The object,—to create a printed circuit board for an implant having improved properties in connection with the electrical contacting via the contact points of the conductor tracks on the printed circuit board,—is achieved, according to the present invention, by means of a device for contacting and/or electrostimulation of living tissue cells or nerves with having a printed circuit board having with at least one contact point for electrical contacting, the printed circuit board encompassing comprising a flexible multilayer system with at least one conductor track. In accordance with the invention, the contact points for the conductor track in the multilayer system are galvanically reinforced. To this end, a galvanically reinforced layer is grown onto the already preprocessed contact point, for example by means of a galvanic process. By virtue of the application of one or more additional material layers onto the contact points of the conductor tracks, these latter are mechanically more stably anchored in the printed circuit board in mechanically more stable manner and hence become more reliable in their function.
摘要翻译： 本发明的目的是为了通过印刷电路板上的导体轨迹的接触点，创建一种具有改进的性质与电接触的性质的印刷电路板，根据本发明，通过 用于接触和/或电刺激活组织细胞或神经的装置，其具有具有至少一个用于电接触的接触点的印刷电路板，所述印刷电路板包括具有至少一个导体轨道的柔性多层系统。 根据本发明，多层系统中的导体轨迹的接触点是电流增强的。 为此，将电加强层生长到已经预处理的接触点上，例如通过电镀工艺。 由于在导体轨道的接触点上施加一个或多个附加材料层，这些后者以机械上更稳定的方式机械地更稳定地锚定在印刷电路板中，因此在其功能上变得更可靠。
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公开(公告)号：US11559684B2
公开(公告)日：2023-01-24
申请号：US16631029
申请日：2018-07-13
申请人： PIXIUM VISION SA
发明人： Martin Deterre , Elodie Bouillet
IPC分类号： H01L27/146 , A61N1/36 , A61N1/05
摘要： The present invention relates to photosensitive arrays comprising a plurality of photosensitive elements disposed in or on a suitable substrate. The photosensitive arrays are useful as implants, in particular as retinal implants. Methods for manufacturing such arrays are also provided.
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4.发明申请公开(公告)号：US20220197022A1
公开(公告)日：2022-06-23
申请号：US17593276
申请日：2020-03-27
申请人： PIXIUM VISION SA
发明人： Martin DETERRE , Ralf HORNIG , Emmanuel SIMON , Eric ABHAMON
摘要： The present invention pertains to a projector device for projecting a light beam onto a retina of a human eye, comprising a projector for projecting a light beam from the exterior of a human eye through a pupil of the eye, wherein the projector is configured such that an exit pupil diameter of the light beam is set smaller than an eye pupil diameter of the eye, a corresponding method, and a device comprising such a projector device.
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公开(公告)号：US09636212B2
公开(公告)日：2017-05-02
申请号：US12293788
申请日：2007-01-26
CPC分类号： A61F2/148 , A61F2/14 , A61F9/007 , A61F2220/0008 , A61F2220/0016 , A61N1/0543
摘要： The object of providing a device for reversibly attaching an implant to an eye, with which the implant can be attached in a simple way to the eye and can if necessary be detached or removed from the eye, is achieved according to the present invention by means of a device for attaching an implant by means of a pin that comprises a substantially elongated shaft, wherein the implant includes an implant film for contacting living tissue or nerves in the visual system of the eye and the implant film has an opening through which the shaft of the pin can be at least partially inserted, characterised in that the device includes a holding element that can be arranged on the shaft of the pin so that the holding element engages on the shaft of the pin and is fixed in an attachment position to the pin. By means of the device according to the invention the implant is on the one hand reliably attached, but can if necessary be detached from the retina by removing the holding element or retainer, wherein the pin anchored in the eye does not have to be removed at the same time, but can be re-used. Damage or injury to the tissue of the eye that would otherwise be associated with the removal of the pin can thereby also be avoided.
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公开(公告)号：US09233026B2
公开(公告)日：2016-01-12
申请号：US13931101
申请日：2013-06-28
发明人： Patrick Ziemeck , Marcus Dapper , Christian Kopka , Ralf Hornig
CPC分类号： A61F9/08 , A61N1/36046 , G02B27/017 , G02B2027/0132 , G02B2027/0138 , G02B2027/014
摘要： The task of providing a device which makes it possible for the natural visual faculty of a partially vision-impaired person to be restored or supported as realistically as possible by means of a visual aid or visual prosthesis is achieved with the visual aid according to the invention in that, beyond the pure acquisition of a two-dimensional image, additional information is included in the image processing. For this purpose, a visual aid system is proposed which, during the reproduction of the processed image, visualizes additional information regarding the spatial position and/or specific attributes of objects in the acquired image which is associated with objects in the acquired image. The present invention thus affords the advantage that a three-dimensional image of the current environment of the user can be acquired owing to the fact that the image visualized to the user by the visual aid system according to the invention comprises additional information, for example, about the relative distance of the objects contained in the image and a depth-selective representation of the acquired image can thus be achieved.
摘要翻译： 使用根据本发明的视觉辅助功能来实现提供使得部分视力受损的人的自然视觉学科可能通过视觉辅助或视觉假体尽可能实际地恢复或支持的装置的任务 因为除了二维图像的纯粹获取之外，附加信息被包括在图像处理中。 为此，提出了一种视觉辅助系统，其在处理的图像的再现期间可视化与所获取的图像中的对象相关联的获取的图像中的对象的空间位置和/或特定属性的附加信息。 因此，本发明的优点在于，由于根据本发明的视觉辅助系统对用户可视化的图像包括附加信息，所以可以获取用户的当前环境的三维图像， 可以实现关于包含在图像中的对象的相对距离和所获取的图像的深度选择性表示。
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公开(公告)号：US20220023645A1
公开(公告)日：2022-01-27
申请号：US17296685
申请日：2019-12-09
申请人： PIXIUM VISION SA
摘要： The present invention relates to the field of electronic devices, in particular implantable electronic devices, e.g. for bio-medical applications, and more particularly, to hermetically packaged electronic devices for bio-medical in vivo applications and packaging methods for such electronic devices.
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公开(公告)号：US09452289B2
公开(公告)日：2016-09-27
申请号：US14005818
申请日：2012-03-19
IPC分类号： A61N1/05 , A61N1/36 , A61B5/0496 , A61B5/00
CPC分类号： A61N1/36046 , A61B5/0496 , A61B5/4851 , A61B5/6821 , A61B5/7264 , A61N1/0543
摘要： Retinal prostheses are configured to apply retinal stimulus signals based on retinal cell classification such as cell types or cell clusters identified based on retinal cell signals. Cell types are identified based on spontaneous or induced retinal electrical signals and analyzed based on temporal patterns of electrical activity, spatio-temporal voltage waveforms, and signal correlations that can be obtained from temporal spike patterns. Cell type indications are stored, and a signals are applied to the retina based on the stored cell type indications.
摘要翻译： 视网膜假体配置为基于视网膜细胞分类应用视网膜刺激信号，例如基于视网膜细胞信号识别的细胞类型或细胞簇。 基于自发或诱导的视网膜电信号识别细胞类型，并且基于可从时间尖峰图案获得的电活动，时空电压波形和信号相关性的时间模式进行分析。 存储细胞类型指示，并且基于存储的细胞类型指示将信号施加到视网膜。
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公开(公告)号：US20150352360A1
公开(公告)日：2015-12-10
申请号：US14656428
申请日：2015-03-12
申请人： PIXIUM VISION SA
发明人： Hans-Jürgen Tiedtke
CPC分类号： A61N1/36046 , A61N1/025 , A61N1/0543 , A61N1/3787
摘要： The present invention relates to a microelectronics element, such as an optical receiver element, for a medical implant device to be implanted in the human or animal body, particularly for a retinal implant device. The microelectronics element comprises a functional unit including application specific microelectronics, such as a photodiode, for performing a function in the medical implant device, and rectifier means adapted for converting an AC supply voltage into a DC voltage. The DC voltage provided by the rectifier means, or an operating voltage derived from the DC voltage, is configured to be supplied to the functional unit. Further, the functional unit and the rectifier means are integrated on a common semiconductor substrate and configured such that the rectifier means isolates the microelectronics element from application of an external DC supply voltage. The invention also relates to a medical implant device, such as a retinal implant, which incorporates such a microelectronics element.
摘要翻译： 本发明涉及一种微电子元件，例如光接收元件，用于植入人体或动物体内的医疗植入装置，特别是用于视网膜植入装置。 微电子元件包括功能单元，其包括用于在医用植入装置中执行功能的诸如光电二极管的特定应用的微电子学，以及适于将AC电源电压转换为DC电压的整流装置。 由整流装置提供的直流电压或从直流电压导出的工作电压被配置为提供给功能单元。 此外，功能单元和整流器装置集成在公共半导体衬底上，并且被配置为使得整流器装置将微电子元件与外部DC电源电压的应用隔离。 本发明还涉及一种医疗植入装置，例如视网膜植入物，其结合了这种微电子元件。
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公开(公告)号：US09079042B2
公开(公告)日：2015-07-14
申请号：US12921728
申请日：2008-03-20
CPC分类号： A61N1/3787 , A61F9/08 , A61N1/36046
摘要： A power supply for a retina implant at least partly located in the interior of a patient's eye is described. The power supply comprises a first transmission coil (4, 23), a second transmission coil (5, 24). The power supply further comprises a signal generation unit adapted for generating a first high frequency signal and a second high frequency signal, and for applying the first high frequency signal to the first transmission coil and the second high frequency signal to the second transmission coil, the second high frequency signal being phase shifted relative to the first high frequency signal. The first transmission coil is adapted for transmitting the first high frequency signal, and the second transmission coil is adapted for transmitting the second high frequency signal.
摘要翻译： 描述了至少部分位于患者眼睛内部的视网膜植入物的电源。 电源包括第一传输线圈（4,23），第二传输线圈（5,24）。 电源还包括适于产生第一高频信号和第二高频信号的信号产生单元，并且用于将第一高频信号施加到第一传输线圈，将第二高频信号施加到第二传输线圈， 第二高频信号相对于第一高频信号相移。 第一发送线圈适于发送第一高频信号，第二发送线圈适于发送第二高频信号。
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