公开(公告)号：US20040247535A1

公开(公告)日：2004-12-09

申请号：US10491109

申请日：2004-03-26

发明人： Taek-Kyun Kang ,  Young-Ho Kim ,  Jae-Hyun Ahn

IPC分类号： A61K007/16

CPC分类号： A61Q11/00 ,  A61K8/24

摘要： The present invention relates to an oral composition which may prevent or treat sensitive teeth. The oral composition contains potassium phosphates, wherein potassium ions inactivate dental nerves to relieve temporary pains, and phosphates not only prevent the exposure of dentinal tubules, which is the basic cause of sensitive teeth, but also block the exposed dentinal tubules. The oral composition further comprises ursodesoxycholic acid, thereby improving the effect of relieving the pain caused by sensitive teeth.

摘要翻译： 本发明涉及可以预防或治疗敏感牙齿的口腔用组合物。 口服组合物含有磷酸钾，其中钾离子灭活牙神经以缓解临时疼痛，磷酸盐不仅可以防止作为敏感牙齿的基本原因的牙质小管的暴露，而且可以阻挡暴露的牙质小管。 口服组合物还包含熊去氧胆酸，从而改善缓解由敏感牙齿引起的疼痛的效果。

公开(公告)号：US20040241109A1

公开(公告)日：2004-12-02

申请号：US10827724

申请日：2004-04-20

发明人： Rita Parikh

IPC分类号： A61K007/16 ,  A61K007/18

CPC分类号： A61Q11/00 ,  A61K8/33 ,  A61K8/34 ,  A61K8/347 ,  A61K8/365 ,  A61K8/37 ,  A61K8/4913

摘要： The present invention is directed to an oral care composition including a synergistically effective combination of (i) at least one essential oil selected from the group consisting of thymol, menthol, eucalyptol, methyl salicylate, anethol and eugenol, and (ii) at least one lactic acid ingredient selected from the group consisting of lactic acid and salts of lactic acid. The pH of the composition is about 3.0 to about 5.5.

摘要翻译： 本发明涉及一种口腔护理组合物，其包括协同有效组合的（i）至少一种选自百里酚，薄荷醇，桉树脑油，水杨酸甲酯，丁香醇和丁子香酚的精油，和（ii）至少一种 选自乳酸和乳酸盐的乳酸成分。 组合物的pH为约3.0至约5.5。

公开(公告)号：US20040224004A1

公开(公告)日：2004-11-11

申请号：US10297376

申请日：2003-06-20

发明人： Jan Zielinski

IPC分类号： A61K031/70 ,  A61K007/16

CPC分类号： A61Q11/00 ,  A23K20/121 ,  A23K20/147 ,  A23K20/163 ,  A23K50/40 ,  A23L33/10 ,  A23L33/105 ,  A61K8/498 ,  A61K31/70 ,  A61K36/82 ,  A61K45/06 ,  A61K2300/00

摘要： Methods and compositions are directed towards a product comprising a food serving that includes at least one of silymarin, an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, and glucuronic acid in an amount effective to reduce volatile sulfur compounds in breath of an individual at least 10% when the food serving is administered to the individual. Preferred food servings are packaged to form a standard serving size. Thus, particularly contemplated methods comprise a step in which a standard serving size is identified. In a further step, at least one ingredient selected from the group consisting of silymarin, an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, and glucuronic acid is included in the serving size, and in a still further step, the product is advertised as a treatment of bad breath.

摘要翻译： 方法和组合物涉及包含食物的产品，该食品包括有效降低挥发性硫化合物的量的水飞蓟素，抗氧化剂，谷胱甘肽，甲基供体，硫基供体，乙酰辅酶A和葡萄糖醛酸中的至少一种 当个人服食食物时，个体呼吸至少10％。 优选的食品包装以形成标准尺寸。 因此，特别考虑的方法包括识别标准服务大小的步骤。 在另一步骤中，包含水飞蓟素，抗氧化剂，谷胱甘肽，甲基供体，硫基供体，乙酰辅酶A和葡萄糖醛酸中的至少一种成分，其中还包括 一步，产品被广告为口臭的治疗。

公开(公告)号：US20040208834A1

公开(公告)日：2004-10-21

申请号：US10483665

申请日：2004-06-10

发明人： Takashi Koudate ,  Akira Shimotoyodome

IPC分类号： A61K007/16

CPC分类号： C08F290/062 ,  A61K8/8135 ,  A61K8/8152 ,  A61K8/91 ,  A61K31/80 ,  A61Q11/00 ,  Y02A50/406

摘要： The present invention provides an oral-use polymer that is provided with a polymer chain (hereinafter, referred to as polymer chain 1) containing a repetitive structure derived from a monomer having a residue obtained by removing one hydrogen atom from one kind or more of phosphorus-containing acids selected from the group consisting of phosphoric acid, polyphosphoric acid, phosphonic acid, polyphosphonic acid, phosphinic acid, partial esters thereof and salts thereof, and a hydrophilic polymer chain (hereinafter, referred to as polymer chain 2), as well as a composition of such an oral-use polymer. These make it possible to inhibit adsorption of bacterial onto the tooth surface and also to suppress formation of bacterial plaque.

摘要翻译： 本发明提供一种具有聚合物链（以下称为聚合物链1）的口服用聚合物，其含有由具有通过从一种或多种磷中除去一个氢原子获得的残基的单体衍生的重复结构 选自磷酸，多磷酸，膦酸，多膦酸，次膦酸，其偏酯及其盐，和亲水性聚合物链（以下称为聚合物链2）的酸，以及 这种口服用聚合物的组合物。 这些使得可以抑制细菌吸附到牙齿表面上并抑制细菌斑块的形成。

公开(公告)号：US20040175332A1

公开(公告)日：2004-09-09

申请号：US10477056

申请日：2003-11-07

发明人： Horst Westenfelder

IPC分类号： A61K007/16 ,  A61K007/22

CPC分类号： A61Q11/00 ,  A61K8/44 ,  A61K8/676 ,  A61K2800/59

摘要： A method for suppressing discoloration of a composition in which a discoloration suppressing amount of ethylenediaminetetraacetic acid or a salt thereof is incorporated into a composition containing an ascorbic acid derivative. Compositions that resist discoloration containing an ascorbic acid derivative and ethylenediaminetetraacetic acid or a salt thereof, and methods of making such compositions.

摘要翻译： 将含有乙二胺四乙酸或其盐的变色抑制量的组合物的变色抑制在含有抗坏血酸衍生物的组合物中的方法。 抗变色的组合物，其含有抗坏血酸衍生物和乙二胺四乙酸或其盐，以及制备这种组合物的方法。

公开(公告)号：US20040166068A1

公开(公告)日：2004-08-26

申请号：US10370909

申请日：2003-02-20

申请人： The Procter & Gamble Company

发明人： Jayanth Rajaiah ,  Mark Ieuan Edwards ,  Ann Maria Kneipp ,  Jeanine Leslie Winston

IPC分类号： A61K007/16 ,  A61K006/00

CPC分类号： A61K8/894 ,  A61K6/0026 ,  A61K2800/52 ,  A61Q11/00 ,  C08L83/10 ,  C08L83/12

摘要： The present invention relates to a denture adhesive composition comprising a safe and effective adhesive amount of denture adhesive component; a safe and effective amount of an antiplaque/antistain agent selected from the group consisting of dimethicone copolyol, silicone surfactant, aminoalkylsilicone, organosiloxane resin, and mixtures thereof; and a non-aqueous denture adhesive carrier. The present invention further relates to a method of increasing the antiplaque, antistain, and/or antideposition efficacy or effect in the oral cavity of a denture wearer, in need thereof, by applying the above composition to the oral cavity.

摘要翻译： 本发明涉及一种义齿粘合剂组合物，其包含安全有效的义齿粘合剂组分的粘合量; 选自二甲聚硅氧烷共聚多元醇，硅氧烷表面活性剂，氨基烷基硅氧烷，有机硅氧烷树脂及其混合物的安全有效量的抗菌/抗粘剂剂; 和非水性义齿粘合剂载体。 本发明还涉及通过将上述组合物应用于口腔来增加有需要的义齿穿着者的口腔中的抗牙斑，抗粘连，和/或抗沉积功效或效果的方法。

公开(公告)号：US20040146465A1

公开(公告)日：2004-07-29

申请号：US10481853

申请日：2003-12-22

发明人： Koichi Fujisawa

IPC分类号： A61K007/16

CPC分类号： A61Q11/00 ,  A61K8/25 ,  A61K8/466

摘要： An oral composition comprising 0.5 to 10% by weight of an abrasive precipitated silica having a 50 percentile (d50) of particle diameter being 5 nullm or less, a 90 percentile (d90) of particle diameter being 15 nullm or less and an RDA value of 120 or more, and 0.01 to 5% by weight of at least one of sulfosuccinate surfactants represented by general formula (1) 1 nullwherein either X1 or X2 is ROnull (AO)nnull or the like and the other is M2Onull; M1 and M2 are the same or different and each represent hydrogen, alkali metal, etc.; R1 is C8-22 alkyl, etc.; AO is C2-3 oxyalkylene and the average number of moles of AO addition polymerization, nullnnull, is 0 to 20; and B is nullNHnull etc.null

摘要翻译： 一种口服组合物，其包含0.5至10重量％的具有50个百分比（d50）的粒径为5μm或更小的研磨沉淀二氧化硅，90个百分数（d90）的粒径为15μm或更小，RDA值为 120以上0.01〜5重量％的通式（1）表示的磺基琥珀酸盐表面活性剂中的至少一种[其中X1或X2为RO-（AO）n - 等，另一个为M 2 O - ; M1和M2相同或不同，各自表示氢，碱金属等; R1为C8-22烷基等; AO是C2-3氧化烯，AO加成聚合的平均摩尔数“n”为0〜20; B为-NH-等]

公开(公告)号：US20040134010A1

公开(公告)日：2004-07-15

申请号：US10663352

申请日：2003-09-15

申请人： The Gillette Company, a Delaware Corporation

发明人： Mingchih M. Tseng ,  Carl M. Philbrook

IPC分类号： A46B009/04 ,  A61K007/16

CPC分类号： A46B11/00 ,  A61K8/43 ,  A61K8/8135 ,  A61K8/86 ,  A61K2800/43 ,  A61Q11/00 ,  Y10T428/2913 ,  Y10T428/2929 ,  Y10T428/2938 ,  Y10T428/2967 ,  Y10T428/2969 ,  Y10T428/2971

摘要： A sustained-release matrix for dental application includes either an anti-microbial agent or a colorant that is released from the matrix when the matrix contacts water. The preferred matrices include a water-soluble polymer and a water-insoluble support resin.

摘要翻译： 用于牙科应用的持续释放基质包括当基质与水接触时从基质释放的抗微生物剂或着色剂。 优选的基质包括水溶性聚合物和水不溶性支撑树脂。

公开(公告)号：US20040131557A1

公开(公告)日：2004-07-08

申请号：US10475914

申请日：2003-12-10

发明人： Robert D. Kross

IPC分类号： A61K007/16

CPC分类号： A61K8/20 ,  A61C1/0076 ,  A61K6/0017 ,  A61K8/365 ,  A61Q11/00

摘要： This invention relates generally to compositions and methods useful for oral hygiene rinses, and more specifically to oral rinses in which the antimicrobial activity of chlorous acid is supplemented by that of lactic acid as one of a combination of antimicrobial acids, preferably acids which serve to partially convert chlorite ion to chlorous acid.

摘要翻译： 本发明一般涉及用于口腔卫生漂洗的组合物和方法，更具体地涉及口腔冲洗液，其中氯酸的抗微生物活性由乳酸的抗微生物活性补充为抗微生物酸的组合之一，优选酸为部分 将亚氯酸盐离子转化成氯酸。

公开(公告)号：US20040091432A1

公开(公告)日：2004-05-13

申请号：US10700784

申请日：2003-11-03

发明人： Jacques M. Dulin

IPC分类号： A61K007/16 ,  A61K009/70

CPC分类号： A61K8/368 ,  A61K8/19 ,  A61K9/0063 ,  A61Q11/00

摘要： Portable medication delivery system for treatment of bad breath, gingivitis, ANUG, plaque, etc., comprising small, shirt pocket-sized re-closable pouches having 2 to 4 sterile, single-use, disposable, treated cotton rolls carrying a selected periodontal anti-microbial, such as mouthwash, or a fluoride, enzyme or antibiotic composition. The anti-microbial is preferably a neutral, alcohol-free solution, but may be a dry or gel composition. The treated rolls are placed in the upper and/or lower buccal vestibules where they release, over time, the anti-microbial solution. The treatment directly targets the critical areas, tiny nullsulcusnull grooves and spaces between the teeth, both significant reservoirs for bacteria. The rolls are left in place for extended periods, on the order of 5-30 minutes or more, without discomfort and without interfering with normal activities of speaking or travel. Tests show the inventive medicated rolls are truly effective in treatment of bad breath.

摘要翻译： 用于治疗口臭，牙龈炎，ANUG，斑块等的便携式药物输送系统，包括具有2至4个无菌，一次性，一次性处理的棉花卷的小型衬衫口袋尺寸的可重复关闭的小袋，其携带选定的牙周抗 - 微生物，如漱口水，或氟，酶或抗生素组合物。 抗微生物剂优选是中性的，不含醇的溶液，但可以是干燥或凝胶组合物。 经处理的卷被放置在上部和/或下部颊部前庭中，随着时间的推移，它们释放抗微生物溶液。 治疗直接针对关键区域，微小的“沟”凹槽和牙齿之间的空间，两个显着的细菌储存器。 这些卷长时间放置在适当位置，时间为5-30分钟或更长，没有不适，也不干扰正常的演讲或旅行活动。 测试显示，本发明的药物卷在口臭治疗中是真正有效的。