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公开(公告)号:US6087348A
公开(公告)日:2000-07-11
申请号:US328743
申请日:1999-06-09
申请人: Raymond Baker , Neil Roy Curtis , Jason Matthew Elliott , Timothy Harrison , Gregory John Hollingworth , Philip Stephen Jackson , Janusz Jozef Kulagowski , Nadia Melanie Rupniak , Eileen Mary Seward , Christopher John Swain , Brian John Williams
发明人: Raymond Baker , Neil Roy Curtis , Jason Matthew Elliott , Timothy Harrison , Gregory John Hollingworth , Philip Stephen Jackson , Janusz Jozef Kulagowski , Nadia Melanie Rupniak , Eileen Mary Seward , Christopher John Swain , Brian John Williams
IPC分类号: A61K31/44 , A61K31/535 , A61K31/675 , A61K31/4445
CPC分类号: A61K31/44 , A61K31/535 , A61K31/675
摘要: The present invention provides the use of an orally active, long acting, CNS-penetrant NK-1 receptor antagonist for the manufacture of a medicament adapted for oral administration for the treatment or prevention of stress disorders without concomitant therapy with other anti-stress agents, methods of treatment using such a NK-1 receptor antagonist and pharmaceutical compositions comprising it.
摘要翻译: 本发明提供口服活性的长效CNS渗透剂NK-1受体拮抗剂在制备适于口服给药以治疗或预防应激障碍的药物中的用途,而不与其它抗应激剂同时治疗, 使用这样的NK-1受体拮抗剂的药物组合物的方法和包含它的药物组合物。