公开(公告)号：US06756386B1

公开(公告)日：2004-06-29

申请号：US09550379

申请日：2000-04-14

申请人： Dan Peters ,  Gunnar M. Olsen ,  Simon F. Nielsen ,  Elsebet Østergaard Nielsen

发明人： Dan Peters ,  Gunnar M. Olsen ,  Simon F. Nielsen ,  Elsebet Østergaard Nielsen

IPC分类号： A61K314462

CPC分类号： C07D401/02 ,  C07D401/12 ,  C07D403/12

摘要： The present invention relates to novel pyridylether derivatives which are cholinergic ligands at nicotinic Ach receptors. The compounds of the invention are useful for the treatment of conditions, disorders, or diseases involving the cholinergic system of the central nervous system, pain, inflammatory diseases, diseases caused by smooth muscle contractions and as assistance in the cessation of chemical substance abuse.

摘要翻译： 本发明涉及新颖的吡啶基醚衍生物，它们是烟碱型Ach受体的胆碱能配体。 本发明的化合物可用于治疗涉及中枢神经系统的胆碱能系统，疼痛，炎性疾病，由平滑肌收缩引起的疾病以及停止化学物质滥用的协助的疾病，病症或疾病。