公开(公告)号：US06552183B1

公开(公告)日：2003-04-22

申请号：US09633493

申请日：2000-08-07

申请人： Kandasamy Ramasamy ,  Robert Tam ,  Devron Averett

发明人： Kandasamy Ramasamy ,  Robert Tam ,  Devron Averett

IPC分类号： C07H19044

CPC分类号： C07H19/04

摘要： Novel monocyclic L-Nucleoside compounds have the general formula Embodiments of these compounds are contemplated to be useful in treating a wide variety of diseases including infections, infestations, neoplasms, and autoimmune diseases. Viewed in terms of mechanism, embodiments of the novel compounds show immunomodulatory activity, and are expected to be useful in modulating the cytokine pattern, including modulation of Th1 and Th2 response.

摘要翻译： 新型单环L-核苷化合物具有通式。这些化合物的实施方案被认为可用于治疗各种疾病，包括感染，感染，肿瘤和自身免疫性疾病。 从机理来看，新化合物的实施方案显示免疫调节活性，并且预期可用于调节细胞因子模式，包括Th1和Th2应答的调节。