公开(公告)号：US06503761B1

公开(公告)日：2003-01-07

申请号：US09420472

申请日：1999-10-19

申请人： David W. Koenig ,  Brenda M. Nelson ,  Beth Anne Lange

发明人： David W. Koenig ,  Brenda M. Nelson ,  Beth Anne Lange

IPC分类号： G01N33335

CPC分类号： A61Q19/10 ,  A61K8/19 ,  A61K2800/47 ,  Y10S436/806

摘要： A system and method for removing contaminants from a surface. The system is designed to use particles having means thereon which are capable of selectively binding to a contaminant or contaminants of interest. The particles are applied to the surface whereupon the contaminants bind to the particle. When the particle is removed, the desired contaminants are also removed. Preferably, the present invention utilizes magnetic particles having iron therein. The particles may then be readily removed using magnets. The means for binding the contaminant to the particle preferably comprise a ligand or a charge specifically designed to remove the contaminant of interest. The particles may be included in a carrier to facilitate their application to the surface. The invention is especially useful for the removal of contaminants from skin.

摘要翻译： 用于从表面去除污染物的系统和方法。 该系统设计为使用能够选择性地结合污染物或感兴趣的污染物的具有其上的装置的颗粒。 颗粒被施加到表面，因此污染物与颗粒结合。 当除去颗粒时，也去除所需的污染物。 优选地，本发明使用其中具有铁的磁性颗粒。 然后可以使用磁体容易地除去颗粒。 用于将污染物与颗粒结合的方法优选包含特异性设计用于去除感兴趣污染物的配体或电荷。 颗粒可以包含在载体中以便于它们施加到表面。 本发明特别可用于从皮肤去除污染物。

公开(公告)号：US06417011B1

公开(公告)日：2002-07-09

申请号：US09425109

申请日：1999-10-19

申请人： Stefan Miltenyi

发明人： Stefan Miltenyi

IPC分类号： G01N33335

CPC分类号： G01N33/5434 ,  B03C1/002 ,  B03C1/01 ,  B03C1/0332 ,  B03C1/034 ,  G01N2400/22 ,  G01N2446/20 ,  G01N2446/30 ,  G01N2446/90 ,  Y10S436/807 ,  Y10S436/824

摘要： Improvements in the existing procedures and materials for conduct of high gradient magnetic separation (HGMS) are disclosed. The use of plastic coated matrices especially small spheres or balls which form superior magnetic gradient-intensifying supports are disclosed, along with improved methods and apparatus to conduct HGMS. The selection of small spheres in combination with the coating provides for uniform matrices of high stability.

摘要翻译： 公开了用于进行高梯度磁选（HGMS）的现有程序和材料的改进。 公开了使用形成优异的磁梯度增强载体的塑料涂层基质，特别是小球或球，以及改进的用于进行HGMS的方法和装置。 与涂层组合的小球的选择提供了高稳定性的均匀基质。