公开(公告)号：WO2015170190A2

公开(公告)日：2015-11-12

申请号：PCT/IB2015/001424

申请日：2015-04-10

Applicant: CREDO BIOMEDICAL PTE LTD.

Inventor： OU, Chung-pei ,  RAHMAN, Abdur Rub, Abdur ,  SAGAR, Kaushal ,  KAO, Stephen, Chang-chi ,  WINSTON WONG, Jr.

CPC classification number: G01N33/52 ,  C12Q1/6813 ,  G01N33/84 ,  C12Q2527/119 ,  C12Q2563/173

Abstract: The present invention relates to a kit and a device for measuring nucleic acid amplification through colour differentiation wherein said kit contains at least one pH indicator dye, one or more contained amplification reagents. The kit and device of the present invention also are used to detect, measure and/or record enzymatic reactions that result in pH changes. The kit and device provide a mechanism to detect pH change by utilizing a pH indicator dye, thus making it observable with the un-aided eye. The kit contains a device for carrying out said reactions. The device contains at least one container, reagents, a pH indicator, a heating or cooling means where needed and a magnetic component.

Abstract translation: 本发明涉及用于通过颜色分化测量核酸扩增的试剂盒和装置，其中所述试剂盒含有至少一种pH指示剂染料，一种或多种含有扩增试剂。 本发明的试剂盒和装置还用于检测，测量和/或记录导致pH变化的酶反应。 试剂盒和装置提供了通过使用pH指示剂染料来检测pH变化的机制，从而使其可以用无辅助眼睛观察到。 试剂盒包含用于进行所述反应的装置。 该装置包含至少一个容器，试剂，pH指示剂，需要的加热或冷却装置和磁性组分。

公开(公告)号：WO2015033229A2

公开(公告)日：2015-03-12

申请号：PCT/IB2014/002637

申请日：2014-08-28

Applicant: CREDO BIOMEDICAL PTE LTD.

Inventor： CHUNG-PEI, Ou ,  KAUSHAL, Sagar ,  RAHMAN, Abdur Rub, Abdur ,  WINSTON, Wong ,  KAO, Steven, Chang-chi ,  CATIA, Marques

CPC classification number: G01N21/78 ,  C12Q1/686 ,  C12Q1/703 ,  C12Q2600/158 ,  G01N21/80 ,  G01N27/4145 ,  G01N27/4167 ,  G01N33/5438 ,  G01N33/558 ,  G01N33/84 ,  G01N2021/752

Abstract: The present invention relates to assay test devices, and methods and kits for use to monitor, sense, read and display results by using devices with printed electronics, such as batteries, reading devices, and other circuitry and/or using colorimetric means for testing by using a sensitive indicator pH dye, or both.

Abstract translation: 本发明涉及化验测试设备，以及用于通过使用具有印刷电子设备的设备（诸如电池，读取设备和其他电路）来监测，感测，读取和显示结果的方法和套件，以及 /或使用比色法通过使用敏感指示剂pH染料或两者进行测试。