公开(公告)号：WO2017004274A3

公开(公告)日：2017-01-05

申请号：PCT/US2016/040212

申请日：2016-06-29

Applicant: NANTBIOSCIENCE, INC.

Inventor： RABIZADEH, Shahrooz ,  BUZKO, Oleksandr ,  WEINGARTEN, Paul ,  MCFARLANE, Heather ,  TSAI, Connie ,  BENZ, Stephen Charles ,  NIAZI, Kayvan ,  SOON-SHIONG, Patrick

IPC: A61K31/415 ,  A61K31/4453 ,  A61K31/4465 ,  A61K31/538 ,  A61K45/06

Abstract: Various compounds, compositions, and methods for inhibition of Rit1 are presented. In especially preferred aspects, contemplated compounds and compositions are suitable for treatment of cancers and other diseases associated with Rit1 signaling.

公开(公告)号：WO2017004274A2

公开(公告)日：2017-01-05

申请号：PCT/US2016/040212

申请日：2016-06-29

Applicant: NANTBIOSCIENCE, INC.

Inventor： RABIZADEH, Shahrooz ,  BUZKO, Oleksandr ,  WEINGARTEN, Paul ,  MCFARLANE, Heather ,  TSAI, Connie ,  BENZ, Stephen Charles ,  NIAZI, Kayvan ,  SOON-SHIONG, Patrick

IPC: A61K31/415 ,  A61K31/4453 ,  A61K31/4465 ,  A61K31/538 ,  A61K45/06

CPC classification number: A61K31/4196 ,  A61K31/4155 ,  A61K31/4178 ,  A61K31/4439 ,  A61K31/538 ,  A61K45/06 ,  A61P35/00 ,  A61K2300/00

Abstract: Various compounds, compositions, and methods for inhibition of Rit1 are presented. In especially preferred aspects, contemplated compounds and compositions are suitable for treatment of cancers and other diseases associated with Rit1 signaling.

Abstract translation: 介绍了用于抑制Rit1的各种化合物，组合物和方法。 在特别优选的方面，所考虑的化合物和组合物适用于治疗与Rit1信号传导相关的癌症和其他疾病。