METHODS AND SYSTEMS FOR IMMOBILIZING A BIOLOGICAL SPECIMEN FOR MICROSCOPIC IMAGING

    公开(公告)号:WO2020243564A1

    公开(公告)日:2020-12-03

    申请号:PCT/US2020/035311

    申请日:2020-05-29

    Abstract: Embodiments of the present invention generally relate to methods for immobilizing a biological specimen for extended periods of time for image capture. Specific embodiments may be used to support a target specimen in a gel matrix. In some embodiments, the biological specimen may be in liquid form at elevated temperatures, a stain and/or lyse may be added to the biological specimen, and a gelling composition may added. At reduced temperatures, the gelling composition may still the biological specimen to immobilize a biological specimen for extended periods of time for image capture.

    MAINTENANCE MANAGEMENT SYSTEM FOR LABORATORY INSTRUMENTATION

    公开(公告)号:WO2020154456A1

    公开(公告)日:2020-07-30

    申请号:PCT/US2020/014702

    申请日:2020-01-23

    Abstract: A geospatial maintenance server collects information from lab instruments such as usage information, instrument uptime, operational performance, and other characteristics, Such information may be used to identify upcoming maintenance needs for lab instruments, including usage based preventative maintenance, and unanticipated degradation based maintenance. A geospatial maintenance interface is provided that allows a user to select a certain country, region, state, or other geographic area to view information on lab instruments and maintenance needs within that area. The interface may display graphs showing uptime for various time periods, comparisons to uptime in other areas, maps with symbols indicating areas and types of maintenance needs, and per-device descriptions of maintenance needs. The interface may also be used to automate efficient and economical assignment of technicians to address maintenance tasks.

    ANTIMICROBIC SUSCEPTIBILITY TESTING USING MACHINE LEARNING

    公开(公告)号:WO2020142274A1

    公开(公告)日:2020-07-09

    申请号:PCT/US2019/067903

    申请日:2019-12-20

    Abstract: An optimized testing method is used to determine minimum inhibitory concentration (MIC) of a particular antimicrobic for use on a sample. This may include iteratively imaging wells inoculated with the sample and containing various concentrations of the antimicrobic. The images are thereafter processed to determine various characteristic values that are provided as input to a machine learning model.

    INFORMATION TO SUPPORT SCHEDULING ON A LABORATORY INSTRUMENT

    公开(公告)号:WO2020131772A1

    公开(公告)日:2020-06-25

    申请号:PCT/US2019/066693

    申请日:2019-12-17

    Inventor: O'REILLY, Aaron

    Abstract: Aspects of the disclosed technology may be used to implement methods in which a lab instrument may locally schedule testing of a sample selected from one or more samples based upon a set of sample metadata provided by a middleware device. The set of sample metadata describes associated sample tests that are being performed in parallel on other lab instruments. Using such data, a local test of the sample may be scheduled so that the results are available at approximately the same time as results become available for the associated sample tests. Variations may include scheduling based upon further factors, such as need for performing maintenance on a lab instrument and whether an associated test is a screening test that may be followed by a confirmatory test, and may also include using transactional principles to ensure controlled scheduling across multiple lab instruments.

    AUTOMATIC QUALITY CHECK FOR LABORATORY INSTRUMENTS

    公开(公告)号:WO2020033509A1

    公开(公告)日:2020-02-13

    申请号:PCT/US2019/045450

    申请日:2019-08-07

    Abstract: Systems and methods for calibrating laboratory instruments. In an example, a laboratory instrument for testing patient specimens includes a testing apparatus configured to receive a cassette that includes a patient specimen or a quality control specimen. In response to determining that a quality control specimen is present, the instrument obtains a first measurement of a parameter. If the first parameter is outside an expected tolerance, the instrument ceases performing tests on all specimens, the instrument re-tests the quality control specimen to obtain a second measurement of the parameter. If the second measurement is within the expected tolerance, instrument resumes processing of the cassette. If the second measurement is outside the expected tolerance, the instrument indicates that recalibration or service is required.

    LAB INSTRUMENT STATUS MONITORING
    18.
    发明申请

    公开(公告)号:WO2020033301A1

    公开(公告)日:2020-02-13

    申请号:PCT/US2019/045088

    申请日:2019-08-05

    Abstract: A dashboard interface may be displayed on a lab instrument to provide aggregate status information from a plurality of other interfaces organized into a single interface. The aggregate status information may be viewed by a nearby user of the lab instrument, and selecting portions of the information via a touchscreen display will navigate directly to a subsequent interface that may be used to view additional information or make configuration changes relating to the selected information. The dashboard may be used as a screensaver on a lab instrument when the instrument is not in use, or may be navigated to by an active user of a lab instrument, or both.

    SAMPLE TUBE RACK AND SAMPLE TUBE RACK ASSEMBLY

    公开(公告)号:WO2020008413A1

    公开(公告)日:2020-01-09

    申请号:PCT/IB2019/055725

    申请日:2019-07-04

    Abstract: A sample tube rack (10) for receiving at least one sample tube is provided, comprising: a bottom surface (12) comprising at least one opening (14) for receiving the sample tube, and at least two guiding elements (16, 16', 16a-d) arranged on the bottom surface (12) adjacent to the opening (14), wherein each guiding element (16, 16', 16a-d) extends substantially parallel to a vertical axis (18) of the opening (14) from the bottom surface (12) towards a top side (20) of the sample tube rack (10). The guiding elements (16.16', 16a-d) are arranged at different positions (l7a-d) around the opening (14), such that a tube compartment (24) for receiving the sample tube is formed by the guiding elements (16, 16', 16a-d) and the opening (14), wherein the guiding elements (16, 16', 16a-d) are spaced apart from each other along a perimeter (21) of the opening (14), thereby forming at least two clearances (22) between the guiding elements (16, 16', 16a-d) along the perimeter (21) of the opening (14).

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