公开(公告)号：WO2022146855A1

公开(公告)日：2022-07-07

申请号：PCT/US2021/065016

申请日：2021-12-22

申请人： LAWRENCE LIVERMORE NATIONAL SECURITY, LLC ,  OPCONDYS, INC.

发明人： SAMPAYAN, Kristin Cortella ,  CAPORASO, George James ,  CHEN, Yu-Jiuan ,  SHANG, Clifford C. ,  SAMPAYAN, Stephen E.

IPC分类号： A61N5/10

摘要： Methods, devices and systems for ultra-high dose radiotherapy are disclosed. The described techniques rely in-part on active switching control of a photoconductive switch during the time the accelerator is accelerating charged particles to produce the output radiation at the desired dose rates. One flash radiotherapy system includes an induction accelerator, and a controllable switch coupled to the induction accelerator. The switch is operable to produce a plurality of voltage pulses to drive the induction accelerator. The radiotherapy system also includes a radiation measurement device to measure output radiation produced by the radiotherapy system and provide feedback to the controllable switch. The controllable switch is operable to, based on the received feedback, modify an amplitude, shape, spacing, number or width of the voltage pulses that are supplied to the particle accelerator to deliver the desired output radiation.

公开(公告)号：WO2022144538A1

公开(公告)日：2022-07-07

申请号：PCT/GB2021/053348

申请日：2021-12-17

申请人： ELEKTA LIMITED

发明人： ROBERTS, David

IPC分类号： A61N5/10

摘要： Disclosed herein is a radiotherapy apparatus comprising a radiation source configured to emit a beam of radiation having a central axis, a multi-leaf collimator, MLC, for shaping the beam of radiation emitted by the radiation source, wherein the MLC comprises a plurality of leaves, and a detection device for detecting radiation emitted by the radiation source. The detection device comprises a first detector arranged to detect a position of the central axis, wherein the first detector comprises a two dimensional array of pixels for generating a two dimensional map of radiation intensity, and at least one second detector arranged to detect a position of each leaf of the plurality of leaves.

公开(公告)号：WO2022141568A1

公开(公告)日：2022-07-07

申请号：PCT/CN2020/142497

申请日：2020-12-31

申请人： 深圳市奥沃医学新技术发展有限公司

发明人： 何冰 ,  闫浩

IPC分类号： A61N5/10 ,  A61B6/00

摘要： 一种放疗系统，包括：机架（100）、射源装置（200）以及影像设备（300）；射源装置（200）设置于机架（100）上；射源装置（200）用于对患者进行射线照射治疗，射源装置（200）通过翻转在不同工作位之间进行转换；影像设备（300）用于对患者身体的部分进行成像。放疗系统可以使射源装置（200）处于不同工作位置，并且通过增加影像设备（300）能够保证摆位过程中的摆位精度更高，使射线照射的效果更加理想，避免对患者的其他区域造成损伤。在放疗系统进行治疗时，可以利用影像设备（300）进行实时成像，从而确保靶区和射线照射区域的位置精度，并且可以实时检测射线束的剂量，以确保治疗的效果。

公开(公告)号：WO2022140987A1

公开(公告)日：2022-07-07

申请号：PCT/CN2020/140390

申请日：2020-12-28

申请人： 西安大医集团股份有限公司

发明人： 付凯强 ,  李超 ,  李立谏 ,  王中亚

IPC分类号： A61N5/10

摘要： 一种图像引导配合方法、系统、电子设备及计算机存储介质。其中，方法包括：根据患者的靶点的放射治疗计划，确定靶点的拉弧照射信息，并将靶点的拉弧照射信息发送至下位机（50），使得下位机（50）根据靶点的拉弧照射信息，控制图像引导放射治疗设备（60）对靶点拉弧照射（S101）；当接收到下位机（50）发送的用于指示目标次拉弧照射开始的标识消息时，根据标识消息，确定靶点的目标次拉弧照射信息，并向上位机（40）的图像引导控制系统发送靶点的目标次拉弧照射信息，使得图像引导控制系统根据靶点的目标次拉弧照射信息，控制图像引导放射治疗设备（60）执行图像引导操作（S102）。该方法能够在对靶点拉弧照射时实时检测靶点的位置，以确保对靶点拉弧照射的位置的准确性。

公开(公告)号：WO2022136839A1

公开(公告)日：2022-06-30

申请号：PCT/GB2021/053336

申请日：2021-12-16

申请人： ELEKTA LIMITED

发明人： WIBERG, Kristian ,  CARLSSON, Per

IPC分类号： A61N5/10

摘要： A radiotherapy apparatus is described. The radiotherapy apparatus comprises a radiation source, a beam shaping apparatus, a beam receiving apparatus, and a controller configured to control the beam shaping apparatus. The radiation source is configured to deliver radiation in each of a coplanar configuration and at least one non-coplanar configuration. The beam shaping apparatus is configured to direct the radiation produced by the radiation source towards the beam receiving apparatus in each of the coplanar configuration and the at least one non-coplanar configuration. The controller is configured to control the beam shaping apparatus to apply a limit on a field of radiation produced by the radiation source based on whether the radiation source is configured in the coplanar configuration or the at least one non-coplanar configuration.

公开(公告)号：WO2022130680A1

公开(公告)日：2022-06-23

申请号：PCT/JP2021/028894

申请日：2021-08-04

申请人： 株式会社日立製作所

发明人： 中島　裕人

IPC分类号： H05H7/04 ,  H05H7/10 ,  H05H13/02 ,  G21K5/04 ,  A61N5/10

摘要： 磁場と加速器内壁の間におけるベータトロン振動によるビームロスを低減する技術を提供する。加速器は、ヨークの内部に円筒状領域を構成し、円筒状領域に静磁場を形成する主電磁石と、荷電粒子ビームを主電磁石の内部から外部へ輸送するビーム出射経路と、静磁場中を周回する荷電粒子ビームを加速するための、周波数を変調した加速電場を印加する加速電場印加器と、加速電場により加速した荷電粒子ビームのベータトロン振動の振幅を増大させるキッカと、を有し、主電磁石は、キッカによりベータトロン振動の振幅が増大した荷電粒子ビームを前記ビーム出射経路に進入させるための第１磁場と、ヨーク内の静磁場の領域とヨークの内壁の間における荷電粒子ビームの発散を抑制するための第２磁場とを作成する。

公开(公告)号：WO2022120487A1

公开(公告)日：2022-06-16

申请号：PCT/CA2021/051769

申请日：2021-12-09

申请人： ELEKTA LIMITED [CA]/[CA]

发明人： NOVOSAD, Philip P. ,  BERIAULT, Silvain

IPC分类号： A61N5/10 ,  G06N3/04 ,  G06N3/08 ,  G06T7/10 ,  G16H30/40

摘要： Systems and methods are disclosed for performing operations comprising: receiving first and second images depicting an anatomy of a subject; obtaining a segmentation associated with the first image; applying a trained neural network to estimate the adapted segmentation corresponding to the anatomy depicted in the second image, the trained network consisting of two sub-networks: a registration sub-network, generating an initial segmentation estimate representing a deformation of the segmentation associated with the first image to fit the anatomy depicted in the second image, and a segmentation refinement sub-network, predicting a refined segmentation for the second image given the initial segmentation estimate.

公开(公告)号：WO2022114829A1

公开(公告)日：2022-06-02

申请号：PCT/KR2021/017573

申请日：2021-11-26

申请人： 한국원자력의학원

发明人： 조일성 ,  홍봉환 ,  박차원 ,  민선홍 ,  김민호 ,  황원택 ,  김경민 ,  박승우

IPC分类号： A61N5/10 ,  A61K41/00

摘要： 본 발명은, 중성자 빔의 이동경로상에 형성되는 공간을 포함하는 차폐하우징, 차폐하우징의 전방에, 가속기를 통과한 입자빔이 조사되도록 구성되는 타겟, 차폐하우징의 후방에 구비되며, 중성자빔의 통과영역을 조절할 수 있도록 구성되는 콜리메이터 및 공간에 삽입될 수 있도록 구성되며, 중성자빔의 에너지를 감소시킬 수 있도록 구성되는 복수의 필터 모듈을 포함하며, 복수의 필터 모듈은 사용자의 선택에 따라 개수가 선택되어 하우징 내에 삽입될 수 있도록 구성되는 붕소중성자 포획치료 장치용 빔 성형장치 및 이를 포함하는 붕소중성자 포획치료장치에 관한 것이다. 본 발명에 따른 붕소 중성자 포획치료 장치용 빔 성형장치 및 이를 포함하는 붕소 중성자 포획치료장치는 중성자 발생 전 사용자가 미리 필터 모듈의 개수를 선택하여 배치하여 열외 중성자의 확보를 극대화활 수 있으므로, 붕소 중성자 포획치료시 치료효과를 향상시킬 수 있고, 부작용을 최소화 할 수 있는 효과가 있다.

公开(公告)号：WO2022112297A1

公开(公告)日：2022-06-02

申请号：PCT/EP2021/082771

申请日：2021-11-24

申请人： POPOWSKI, Georg

发明人： POPOWSKI, Georg

IPC分类号： A61N5/10 ,  A61B90/00 ,  A61B90/14 ,  A61B90/17 ,  A61B34/30

摘要： Provided is a positioning tool (200) for assisting treatment of a subject in an external radiotherapy programme comprising two or more external radiotherapy treatment sessions comprising: a steering guide (300) having a rigid handle portion (316) disposed at the proximal end (40) in fixed relation to an effector shaft (310) for controlling the position and/or direction of the effector shaft (310), wherein the handle portion (316) is provided with a grip locator (300) configured for position-repeatable co-operation with a gripper (432) of a robotic arm (400), wherein the gripper (432) has an open state and a closed state; wherein the grip locator (300) is configured to be seated within the gripper (432) in the closed state, in which movements of the seated grip locator (300) relative to the gripper (432) are limited and prevented.

公开(公告)号：WO2022112058A1

公开(公告)日：2022-06-02

申请号：PCT/EP2021/081849

申请日：2021-11-16

申请人： RAYSEARCH LABORATORIES AB

发明人： TRANEUS, Erik

IPC分类号： A61N5/10

摘要： A radiotherapy treatment planning method for achieving a FLASH radiotherapy treatment plan involves optimizing the plan using an optimization problem that has been designed to maximize the part of the irradiation that will be delivered under FLASH conditions, in particular to an organ at risk, to minimize the damage to the organ at risk.