公开(公告)号：WO2008093329A2

公开(公告)日：2008-08-07

申请号：PCT/IL2008/000113

申请日：2008-01-24

Applicant: FRUCHTER, Lazar

Inventor： FRUCHTER, Lazar

CPC classification number: A61B1/24 ,  A61B10/0045 ,  A61B10/0096 ,  A61B2010/0003 ,  G01N2333/315

Abstract: A method and kit for detecting a medical condition associated with presence of pathogens in a body sample, the method comprising incubating a body sample thereby to provide an incubated body sample; and performing a rapid test on the incubated body sample to determine one of pathogen presence and pathogen absence.

Abstract translation: 一种用于检测与身体样品中病原体存在相关的医学病症的方法和试剂盒，所述方法包括孵育身体样品从而提供孵化体样品; 并对孵化的身体样品进行快速测试以确定病原体存在和病原体缺失之一。

公开(公告)号：WO2007037707A2

公开(公告)日：2007-04-05

申请号：PCT/NZ2006/000252

申请日：2006-09-29

Applicant: CLARKE, David, Conrad ,  CLARKE, Glenn, Andrew

Inventor： CLARKE, David, Conrad ,  CLARKE, Glenn, Andrew

IPC: F25D16/00

CPC classification number: C09K5/10 ,  A41D13/0053 ,  A61B2010/0003 ,  A61F2007/0065 ,  A61F2007/0233 ,  A61F2007/0261 ,  A62B17/005

Abstract: A cooling device, which includes a cooling solution and an absorption means; such that the cooling solution includes one or more low boiling point alcohols, one or more cooling sensates and water; wherein the total concentration of low boiling point alcohols is between 5% and 25% of the cooling solution; the total concentration of cooling sensates is up to 20% of the cooling solution, and the concentration of any single cooling sensate is a maximum of 10% of the cooling solution; and the water concentration is at least 50% of the cooling solution, wherein at least part of the absorption means is configured to releasably absorb any cooling solution applied to it and, in use, allow contact between a user's skin and the cooling solution; and wherein said absorption means is a flexible garment configured to closely fit one or more body parts of the user.

Abstract translation: 一种冷却装置，包括冷却溶液和吸收装置; 使得冷却溶液包括一种或多种低沸点醇，一种或多种冷却感和水; 其中低沸点醇的总浓度在冷却溶液的5％至25％之间; 冷却液的总浓度高达冷却液的20％，任何单一冷却液的浓度最多为冷却溶液的10％; 并且所述水浓度为所述冷却溶液的至少50％，其中所述吸收装置的至少一部分构造成可释放地吸收施加到其上的任何冷却溶液，并且在使用中允许使用者的皮肤与所述冷却溶液之间的接触; 并且其中所述吸收装置是被配置为紧密地配合使用者的一个或多个身体部位的柔性衣服。

公开(公告)号：WO2006050033B1

公开(公告)日：2006-12-14

申请号：PCT/US2005038786

申请日：2005-10-27

Applicant: SONTRA MEDICAL CORP ,  KELLOGG SCOTT C ,  CHUANG HAN

Inventor： KELLOGG SCOTT C ,  CHUANG HAN

IPC: A61B5/05

CPC classification number: A61B5/681 ,  A61B5/14514 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150083 ,  A61B5/150358 ,  A61B5/150969 ,  A61B5/15134 ,  A61B5/157 ,  A61B10/0045 ,  A61B2010/0003

Abstract: The invention relates to a transdermal analyte monitoring system comprising a medium adapted to interface with a biological membrane and to receive an analyte from the biological membrane and an electrode assembly comprising a plurality of electrodes, wherein the medium is adapted to react continuously with the analyte, an electrical signal is detected by the electrode assembly, and the electrical signal correlates to an analyte value. The analyte value may be the flux of the analyte through the biological membrane or the concentration of the analyte in a body fluid of a subject. The medium may comprise a vinyl acetate based hydrogel, an agarose based hydrogel, or a polyethylene glycol diacrylate (PEG-DA) based hydrogel, for example. The surface region of the electrode may comprise pure platinum. The system may include an interference filter located between the biological membrane and the electrode assembly for reducing interference in the system. The system may comprise a processor programmed to implement an error correction method that corrects for sensor drift.

公开(公告)号：WO2006130482A2

公开(公告)日：2006-12-07

申请号：PCT/US2006020489

申请日：2006-05-25

Applicant: STAT MEDICAL DEVICES INC ,  SCHRAGA STEVEN

Inventor： SCHRAGA STEVEN

CPC classification number: A61B5/15194 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150183 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150824 ,  A61B5/150908 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15186 ,  A61B5/1519 ,  A61B17/32093 ,  A61B2010/0003 ,  A61B2562/0295

Abstract: Cap (1) for a testing device (100). The cap (1) includes a lancet (L) movably mounted within the cap (1) and a skin-engaging end (3) having an opening (5) that allows a portion of a needle (N) of the lancet (L) to pass therethrough. A test strip (6a/6b) may be arranged on the cap (1).

Abstract translation: 用于测试装置（100）的盖（1）。 盖（1）包括可移动地安装在盖（1）内的刺血针（L）和皮肤接合端（3），其具有允许刺血针（L）的针（N）的一部分的开口（5） 通过。 测试条（6a / 6b）可以布置在盖（1）上。

公开(公告)号：WO2006129195A2

公开(公告)日：2006-12-07

申请号：PCT/IB2006001723

申请日：2006-05-26

Applicant: APROVIX AB ,  LUNDKVIST ULF ,  SJOBERG BERNDT ,  WILLANDER ERIK ,  NYGREN SOREN

Inventor： LUNDKVIST ULF ,  SJOBERG BERNDT ,  WILLANDER ERIK ,  NYGREN SOREN

IPC: A61B10/02 ,  A61B10/00

CPC classification number: A61B10/0096 ,  A61B10/0051 ,  A61B10/0291 ,  A61B2010/0003 ,  A61B2010/0074 ,  A61B2017/00473

Abstract: A sampling system comprises a mailing package; a cell sampling device comprising a flexible shaft having a handle at one end, wherein the shaft is configured to allow an individual to self collect a cell sample from mucous tissue, and a sample collecting element removably connectable with the other end of the shaft and operable to collect a cell sample from mucous tissue of an individual; and a sealable unit, wherein the unit is configured to store the sample collecting element having a cell sample thereon and to be received within the mailing package in its sealed form. The system may optionally further include a transport package configured to receive the remaining components of the system for delivery to a user.

Abstract translation: 采样系统包括邮寄包装; 细胞取样装置，其包括在一端具有手柄的柔性轴，其中所述轴构造成允许个体自身从粘液组织收集细胞样品，以及样品收集元件，其可拆卸地与所述轴的另一端连接并可操作 从个体的粘液组织收集细胞样品; 以及可密封单元，其中所述单元被配置为将其上具有电池样品的样品收集元件存储在其密封形式的所述邮寄包装内。 系统可以可选地进一步包括被配置为接收系统的剩余组件以传送给用户的传输包。

公开(公告)号：WO2006050033A3

公开(公告)日：2006-11-02

申请号：PCT/US2005038786

申请日：2005-10-27

Applicant: SONTRA MEDICAL CORP ,  KELLOGG SCOTT C ,  CHUANG HAN

Inventor： KELLOGG SCOTT C ,  CHUANG HAN

IPC: A61B5/05

CPC classification number: A61B5/681 ,  A61B5/14514 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150083 ,  A61B5/150358 ,  A61B5/150969 ,  A61B5/15134 ,  A61B5/157 ,  A61B10/0045 ,  A61B2010/0003

Abstract: The invention relates to a transdermal analyte monitoring system comprising a medium adapted to interface with a biological membrane and to receive an analyte from the biological membrane and an electrode assembly comprising a plurality of electrodes, wherein the medium is adapted to react continuously with the analyte, an electrical signal is detected by the electrode assembly, and the electrical signal correlates to an analyte value. The analyte value may be the flux of the analyte through the biological membrane or the concentration of the analyte in a body fluid of a subject. The medium may comprise a vinyl acetate based hydrogel, an agarose based hydrogel, or a polyethylene glycol diacrylate (PEG-DA) based hydrogel, for example. The surface region of the electrode may comprise pure platinum. The system may include an interference filter located between the biological membrane and the electrode assembly for reducing interference in the system. The system may comprise a processor programmed to implement an error correction method that corrects for sensor drift.

Abstract translation: 本发明涉及一种透皮分析物监测系统，该系统包括适于与生物膜界面接触并从生物膜接收分析物的介质和包含多个电极的电极组件，其中该介质适于与分析物连续反应， 电信号被电极组件检测到，并且电信号与分析物值相关。 分析物值可以是分析物通过生物膜的通量或者受试者体液中分析物的浓度。 例如，介质可以包含基于乙酸乙烯酯的水凝胶，基于琼脂糖的水凝胶或基于聚乙二醇二丙烯酸酯（PEG-DA）的水凝胶。 电极的表面区域可以包含纯铂。 该系统可以包括位于生物膜和电极组件之间的干扰滤波器，用于减少系统中的干扰。 该系统可以包括处理器，该处理器被编程为实施纠正传感器漂移的纠错方法。

公开(公告)号：WO2006050032A3

公开(公告)日：2006-09-08

申请号：PCT/US2005038785

申请日：2005-10-27

Applicant: SONTRA MEDICAL CORP ,  CHUANG HAN ,  BARMAN SHIKHA P

Inventor： CHUANG HAN ,  BARMAN SHIKHA P

IPC: A61B5/05

CPC classification number: A61B5/681 ,  A61B5/14514 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150083 ,  A61B5/150358 ,  A61B5/150969 ,  A61B5/15134 ,  A61B5/157 ,  A61B10/0045 ,  A61B2010/0003

Abstract: The invention relates to a transdermal analyte monitoring system comprising a medium adapted to interface with a biological membrane and to receive an analyte from the biological membrane and an electrode assembly comprising a plurality of electrodes, wherein the medium is adapted to react continuously with the analyte, an electrical signal is detected by the electrode assembly, and the electrical signal correlates to an analyte value. The analyte value may be the flux of the analyte through the biological membrane or the concentration of the analyte in a body fluid of a subject. The medium may comprise a vinyl acetate based hydrogel, an agarose based hydrogel, or a polyethylene glycol diacrylate (PEG-DA) based hydrogel, for example. The surface region of the electrode may comprise pure platinum. The system may include an interference filter located between the biological membrane and the electrode assembly for reducing interference in the system. The system may comprise a processor programmed to implement an error correction method that corrects for sensor drift.

Abstract translation: 本发明涉及一种透皮分析物监测系统，其包括适于与生物膜接合并接收来自生物膜的分析物的介质和包含多个电极的电极组件，其中所述介质适于与分析物连续反应， 电信号由电极组件检测，电信号与分析物值相关。 分析物值可以是通过生物膜的分析物的通量或受试者的体液中分析物的浓度。 介质可以包括例如基于乙酸乙烯酯的水凝胶，基于琼脂糖的水凝胶或基于聚乙二醇二丙烯酸酯（PEG-DA）的水凝胶。 电极的表面区域可以包括纯铂。 该系统可以包括位于生物膜和电极组件之间的干涉滤波器，用于减少系统中的干扰。 系统可以包括被编程为实现校正传感器漂移的纠错方法的处理器。

公开(公告)号：WO2006088904A2

公开(公告)日：2006-08-24

申请号：PCT/US2006005237

申请日：2006-02-15

Applicant: GAO PING

Inventor： GAO PING

IPC: G01N33/53 ,  A61M31/00

CPC classification number: A61B10/0038 ,  A61B10/0096 ,  A61B2010/0003 ,  G01N1/38 ,  G01N33/558 ,  G01N33/56983 ,  G01N2001/028 ,  G01N2035/00108 ,  G01N2333/14

Abstract: The present invention includes devices and methods for the detection of an analyte in a fecal sample. The fecal sample test device includes a sample collection structure and sample collection housing, a detection housing, a fecal suspension solution or fecal dilution solution, a detection housing capable of attachment to the collection housing and an analyte detecting means. When attached, the collection housing permits a portion of liquid extracted sample to fluidly flow into the detection housing where the analyte detection means detects the presence or quantity of an analyte suspected of being present in the fecal sample.

Abstract translation: 本发明包括用于检测粪便样品中的分析物的装置和方法。 粪便样本测试装置包括样本收集结构和样本收集壳体，检测壳体，粪便悬浮液或粪便稀释溶液，能够附着到收集壳体的检测壳体和分析物检测装置。 当附接时，收集壳体允许液体提取样品的一部分流体流入检测壳体，其中分析物检测装置检测到疑似存在于粪便样品中的分析物的存在或数量。

公开(公告)号：WO2005072398A2

公开(公告)日：2005-08-11

申请号：PCT/US2005/002684

申请日：2005-01-27

Applicant: BAMBURGH MARRSH LLC

Inventor： SLOWEY, Paul, D. ,  HERRIG, Richard ,  WICKSTEAD, James ,  ENNIS, John ,  SMITH, Paul

IPC: A61B10/00 ,  A61B10/02 ,  B01L3/00 ,  B01L99/00

CPC classification number: A61B10/02 ,  A61B10/0051 ,  A61B2010/0003 ,  B01L3/5029 ,  B01L2300/027

Abstract: A specimen sample collection device includes a handle having a sufficiency indicator and an absorbent pad partially contained within said handle. A specimen sample collection device and test system includes a handle having a sufficiency indicator, an absorbent pad partially contained within said handle, a pad compression tube insertable over said absorbent pad within said handle and around an end of said handle, and a collection tube having one or more sample chambers, attachable to said pad compression tube, and wherein said compression tube defines one or more chambers, and wherein when said collection tube is attached to said pad compression tube, the chambers are in fluid communication with said pad compression tube. A specimen sample collection device including a sufficiency indicator made up of a light pipe indicator window. A specimen sample collection device including an absorbent pad split and divided into two lengths connected at a base. A specimen sample collection device including a bar code identification. A specimen sample collection device and test system including a lock and key securing mechanism. A specimen sample collection device including a handle one or more analyte test strips. A specimen sample collection device and test system including a reader.

Abstract translation: 样本采集装置包括具有足够指示器的手柄和部分地包含在所述手柄内的吸收垫。 样本采集装置和测试系统包括具有足够指示器的手柄，部分地包含在所述手柄内的吸收垫，可插入所述手柄内的所述吸收垫上并围绕所述手柄的端部的垫压缩管，以及收集管， 一个或多个样品室，可附接到所述垫压缩管，并且其中所述压缩管限定一个或多个室，并且其中当所述收集管附接到所述垫压缩管时，所述室与所述垫压缩管流体连通。 一种样本采集装置，包括由光管指示器窗口组成的足够指示器。 一种标本样品收集装置，包括分开并分成在基部连接的两个长度的吸收垫。 包括条形码识别的样本采集装置。 标本采集装置和测试系统，包括锁和钥匙固定机构。 包括手柄的一个或多个分析物测试条的样本采集装置。 标本样本收集装置和包括阅读器的测试系统。

公开(公告)号：WO02062234A3

公开(公告)日：2003-08-07

申请号：PCT/US0148843

申请日：2001-12-11

Applicant: INTEGRATED VASCULAR SYS INC

Inventor： GINN RICHARD S ,  SALMON STEPHEN M ,  JABBA RONALD J

IPC: A61B17/08 ,  A61B10/00 ,  A61B17/00 ,  A61B17/12

CPC classification number: A61B17/0057 ,  A61B2010/0003 ,  A61B2017/00004 ,  A61B2017/00637 ,  A61B2017/00654 ,  A61B2017/00898

Abstract: An apparatus for sealing a passage through tissue includes an elongate shaft and a cylindrical plug disposed on a distal end of the shaft, the plug including a helical thread on its outer surface. Intestinal submucosa may be secured to the plus, e.g., in a cavity in its distal end, that may be delivered into the passage. Alternatively, the plug may be formed from a bioabsorbable material and may be released from the shaft within the passage. The plug is threaded into the passage, thereby engaging the tissue to seal the passage. The shaft is rotated until it engages a blood vessel within the tissue while monitoring blood flow through the vessel. The shaft is rotated to thread the plug into the passage until blood flow ceases through the vessel, whereupon rotation of the shaft is reversed to back the plug until blood flow through the vessel resumes.

Abstract translation: 用于密封通过组织的通道的装置包括细长轴和设置在轴的远端上的圆柱塞，该塞在其外表面上包括螺旋形螺纹。 肠粘膜下层可以固定到加上，例如在其远端的空腔中，其可以被输送到通道中。 或者，塞子可以由生物可吸收材料形成并且可以在通道内从轴释放。 塞子被拧入通道中，从而接合组织以密封通道。 旋转轴直到其与组织内的血管接合，同时监测通过血管的血流。 轴被旋转以将塞子螺纹连接到通道中，直到血流停止通过血管，由此轴的旋转被反向以回到塞子，直到通过血管的血液流动恢复。