摘要:
Methods for treating infection and related compositions, compounds of formula (I) as defined in the application and methods for preparing same, are provided. In general, the compounds inhibit tarnsfer ribonucleic acid (tRNA) synthetase and are useful as antimicrobial agents.
摘要:
Compounds having formula (I) are inhibitors of 5-lipoxygenase and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, psoriasis, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
摘要:
Alpha-adrenoceptor antagonists having formula (I), which are useful to produce alpha-adrenoceptor antagonism, pharmaceutical compositions including these antagonists, and methods of using these antagonists to produce alpha-adrenoceptor antagonism in mammals.