-
61.发明申请
公开(公告)号：WO2021021771A1
公开(公告)日：2021-02-04
申请号：PCT/US2020/043808
申请日：2020-07-28
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： VANAPALLI, Siva , KAMYABI, Nabiollah , PORE, Adity , AHMED, Shamim , BITHI, Swastika, S.
Abstract: The present invention includes a device and a method of using the device, wherein the device is a microfluidic device for single or multicell capture comprising: a substrate; one or more microgrooves or microtubes disposed within the substrate, each microgroove or microtube having a first end and a second end, wherein a width of the microgroove or microtube is a diameter of a target cell or a group of cells, wherein the microgroove or microtube comprises one or more chambers; a fluid input disposed within the substrate in fluid communication with the first end of the one or more microgrooves or microtube; and a fluid output disposed within the substrate in fluid communication with the second end of the one or more microgrooves or microtube, or the one or more chambers, wherein one or more cells that are captured in the microgroove can be analyzed as a single cell.
-
公开(公告)号：WO2020252493A1
公开(公告)日：2020-12-17
申请号：PCT/US2020/045586
申请日：2020-08-10
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： CHEN, Chau-Chyun
Abstract: The present invention includes a method for thermodynamic formulation of a Langmuir isotherm comprising: (1), (1') (1), (1') where n i is the adsorption amount of gas component i ; (1') is the adsorption maximum amount; P is the gas vapor pressure, and K is the apparent adsorption equilibrium constant in which adsorption and desorption rates are proportional to a concentrations of vacant sites and occupied sites; and substituting the concentration of both a vacant site and an occupied site with site activities, wherein a reference state for the vacant sites is at zero surface coverage while the reference state for the occupied sites is at full surface coverage.
-
公开(公告)号：WO2020181267A1
公开(公告)日：2020-09-10
申请号：PCT/US2020/021574
申请日：2020-03-06
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： CHONG, Jo Woon , ASKARIAN, Behnam , TABEI, Fatemehsadat
IPC: A61B3/107
Abstract: Diagnostic system and method for eye disease detection using a smartphone (308). At least some of the example embodiments are methods including capturing, by way of a camera lens on a device (308), an image of an eye (504) to create a raw specimen, wherein the image of the eye comprises a series of concentric rings on a cornea of the eye; processing the raw specimen to create a processed specimen; performing edge detection on the processed specimen to detect a boundary of a cornea; determining a topography of the eye based on the series of concentric rings; and classifying the processed specimen as including an eye disease, based on the determining the topography.
-
公开(公告)号：WO2020081759A1
公开(公告)日：2020-04-23
申请号：PCT/US2019/056645
申请日：2019-10-17
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： GARG, Himanshu , JOSHI, Anjali
Abstract: The present invention includes composition and methods for making multivalent vaccines for immunization against flavivirus and/or arboviruses including a multivalent Virus Like Particles (VLP) and mixtures thereof, the method comprising: method of making a flavivirus and/or arboviruses Virus Like Particles (VLP) comprising: inserting two or more nucleic acids that encode at least one flavivirus protein into a lentiviral backbone vector; generating a lentivirus by transfecting a first cell line with the lentiviral backbone vector and isolating the lentivirus therefrom; transducing a second cell line with the lentivirus; culturing the transduced cell line under conditions in which the multivalent flavivirus Virus Like Particles (VLP) are released from the cell line; and isolating the flavivirus Virus Like Particles (VLP) from a culture supernatant, wherein a cell line makes a virus-specific VLP, and the VLPs are purified and then mixed in different combinations to make the multivalent vaccine.
-
公开(公告)号：WO2020081716A2
公开(公告)日：2020-04-23
申请号：PCT/US2019/056580
申请日：2019-10-16
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： GILL, Harvinder, Singh , LEE, Chang, Hyun
IPC: C12N5/07
Abstract: The present invention includes a polypeptide for use in a three dimensional (3D) culture system for the growth of cells comprising one or more repeats of a sequence n1-(X 1 X 2 GXP)-n2 (SEQ ID NO: 8), wherein X 1 and X 2 are any amino acids except proline, wherein X 1 and X 2 can be the same or different amino acid in solution or coated on a substrate, wherein n 1 and n 2 are equal to or greater than one, and wherein X is an aliphatic amino acid.
-
Patent Agency Ranking
公开(公告)号：WO2020035805A3
公开(公告)日：2020-02-20
申请号：PCT/IB2019/056902
申请日：2019-08-14
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： GORUMLU, Serdar , AKSAK, Burak
Abstract: A method, system, and apparatus for an improved gripping device comprises a substrate and a curved microplate formed on the substrate. In certain embodiments, the system further comprises an array of curved microplates formed on the substrate further comprising a plurality of aligned rows of the curved microplates formed on the substrate and a plurality of aligned columns of the curved microplates formed on the substrate. The curved microplate has a gripping direction, being substantially opposite the direction of the curve in the curved microplate and the curved microplate has a releasing direction, substantially in line with the direction of the curve in the curved microplate.
-
公开(公告)号：WO2020035805A2
公开(公告)日：2020-02-20
申请号：PCT/IB2019/056902
申请日：2019-08-14
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： GORUMLU, Serdar , AKSAK, Burak
IPC: B29C39/40
Abstract: A method, system, and apparatus for an improved gripping device comprises a substrate and a curved microplate formed on the substrate. In certain embodiments, the system further comprises an array of curved microplates formed on the substrate further comprising a plurality of aligned rows of the curved microplates formed on the substrate and a plurality of aligned columns of the curved microplates formed on the substrate. The curved microplate has a gripping direction, being substantially opposite the direction of the curve in the curved microplate and the curved microplate has a releasing direction, substantially in line with the direction of the curve in the curved microplate.
-
公开(公告)号：WO2019241348A1
公开(公告)日：2019-12-19
申请号：PCT/US2019/036714
申请日：2019-06-12
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： ALTENBERG, Guillermo, A. , CHANG, Cheng-Wei, Tom
IPC: A01N1/02
Abstract: The present invention includes novel molecules and methods of using an amphiphilic kanamycin molecule having substitutions at the O -4", 0-6", or O -4" and 0-6" positions having reduced antimicrobial activity for targeting Connexin Hemichannels.
-
69.发明申请
公开(公告)号：WO2019237050A1
公开(公告)日：2019-12-12
申请号：PCT/US2019/036134
申请日：2019-06-07
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： CHEN, Qiang , SHENG, James, J.
IPC: C09K3/00
Abstract: Method to generate microfractures by chemical reaction in low carbonate mineral content shale reservoirs in which sulfate acid or persulfate compound (such as ammonium persulfate ((NH 4 ) 2 S 2 O 8 ) at a relatively high content) injected into conventional fracturing fluid can react with shale carbonate components resulting in the precipitation reaction of gypsum crystal (CaSO4∙2H2O) to occur because an insoluble calcium sulfate (CaSO 4 ) solid is formed. It has been found that expansion stress generated by rapid crystallization in the shale nanoscale pore space can intensively crack shale rocks without additional energy input. Not only does this lead to the formation of much denser secondary microfracture networks, it also can increase SRV by the micrometer-scale gypsum crystals prohibiting these secondary microfracture networks from closure under a normal stress, thereby, improve the efficiency of hydraulic fracturing and hydrocarbon production.
-
公开(公告)号：WO2019173706A9
公开(公告)日：2019-09-12
申请号：PCT/US2019/021339
申请日：2019-03-08
Applicant: TEXAS TECH UNIVERSITY SYSTEM
Inventor： ABDELGAWAD, Amr
Abstract: The present invention includes a tibio-talar device for providing stabilizing support between a tibia and a talus including: a bone nail adapted to traverse the tibia and the talus, wherein the bone nail is curved such that it traverses the tibia and enters the talus at an angle, wherein the bone nail is angled from lateral to medial, wherein the bone nail is configured to provide for intra medullary fusion of the ankle without obstructing the subtalar joint, wherein the bone nail has openings are positioned along the length of the bone nail, and wherein the screw engages the bone nail to lock its rotation in relation to the tibia and talus and optionally for compression of two or more bones selected from tibia to talus, fibula to tibia, or fibula to talus,
-
-
-
-
-
-
-
-
-
Search Results
253
records
(took 0.029 seconds)
