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1.发明申请CANCER CHEMOTHERAPEUTIC CYCLIC AND ACYCLIC DISULFONIC ESTER COMPOUNDS, METHOD OF USE THEREFOR, AND INTERMEDIATES 审中-公开癌症化疗循环和ACYCLIC DISUFONIC ESTER化合物，其使用方法和中间体
公开(公告)号：WO1985003075A1
公开(公告)日：1985-07-18
申请号：PCT/US1985000057
申请日：1985-01-14
Applicant: CRONYN, Marshall, W.
IPC: C07C143/68
CPC classification number: C07F7/0834 , C07C309/00 , C07D327/00
Abstract: Bifunctional cyclic disulfonic ester compounds effective in treating certain types of cancers. Initial nucleophilic reaction with the compound produces a negatively charged sulfonic acid end-group which remains attached to the compound until a second alkylation reaction can occur.
Abstract translation: 双官能环状二磺酸酯化合物有效治疗某些类型的癌症。 与化合物的初始亲核反应产生负电荷的磺酸端基，其保持与化合物连接，直至发生第二烷基化反应。
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