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公开(公告)号:WO2022255955A1
公开(公告)日:2022-12-08
申请号:PCT/TR2021/050513
申请日:2021-05-31
发明人: KAVAKLI, İbrahim Halil , GÜZEL, Mustafa , AYDIN, Cihan , TÜRKAY, Metin , GÜL, Şeref , ERGÜN, Çağla , ŞAVLUĞ İPEK, Özgecan
IPC分类号: A61K31/517 , A61P3/10 , A61P43/00
摘要: The present invention relates to ((1S,9S)-11-{[4-(1,3-benzodioxol-5-ylamino)-8-methyl-2-quinazolinyl]methyl}-7,11-diazatricyclo[7.3.1.0~2,7~] trideca-2,4-dien-6-one) compound and related derivatives. The compound of the invention is a CRY1/2-binding small molecule and also a stabilizer of CRY1 and CRY2 proteins, and is therefore useful, as pharmaceutical agent, especially in the treatment and/or prevention of disorders associated with the circadian rhythm, including CRY1-mediated diseases such as diabetes.
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2.
公开(公告)号:WO2022235234A2
公开(公告)日:2022-11-10
申请号:PCT/TR2022/050181
申请日:2022-03-01
发明人: GÜZEL, Mustafa , ARPA, Muhammet Davut , ÜSTÜNDAĞ OKUR, Neslihan , ÖNAL, Hasan , ÇAĞLAR, Emre Şefik
IPC分类号: A61K31/00
摘要: The present invention involves synthesizing Angiotensin-1-7 which is a medicine active ingredient on both laboratory and industrial scale in order to be used effectively in Covid-19 treatment, and its new formulations.
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公开(公告)号:WO2022146363A1
公开(公告)日:2022-07-07
申请号:PCT/TR2021/051505
申请日:2021-12-24
发明人: ARSLAN, Hüseyin , SOLAIJA, Muhammad Sohaib Jamal , SULEIMAN, Hanadi Mohammad Youssef , KİHERO, Abuu Bakari , MADNI, Haji Muhammed Furqan Ahmed
摘要: The present invention provides a method to protect wireless communication signals from being overheard/intercepted by malicious eavesdroppers. The method has three main steps: selection of the coordinating transmission points (TPs) for the user whose communication is to be secured, splitting of the data that is to be sent to the aforementioned user into N parts, where N is the number of TPs used and channel based manipulation of the transmitted signal to ensure that delay spread is less than guard duration.
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公开(公告)号:WO2022146362A1
公开(公告)日:2022-07-07
申请号:PCT/TR2021/051504
申请日:2021-12-24
发明人: ARSLAN, Hüseyin , AYGÜL, Mehmet Ali
摘要: The invention relates to a method (100) that enables the following steps to be performed in any order to ensure that at least one attack to be made to any at least one OSI layer and/or to any at least one sub-layer of said OSI layer in communication systems can be predicted/detected and thus precautions are taken in advance; - Creating the training dataset by determining the machine inputs (G) and machine outputs (Ç) in the first step - Making the training datasets understandable by the machine (computer) in the second step - Designing machine learning in the third step - Creating the validation dataset in the fourth step - Training the machine (or trained machine) in the fifth step - Obtaining test data (or sets) in the sixth step - In the seventh step, estimating (or testing) the machine outputs (Ç) using the machine trained in the fifth step and the test input set obtained in the sixth step.
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5.
公开(公告)号:WO2022146361A1
公开(公告)日:2022-07-07
申请号:PCT/TR2021/051503
申请日:2021-12-24
摘要: The invention is related to a method for the model-independent solution of inverse problems with deep learning in image/video processing.
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公开(公告)号:WO2022146360A2
公开(公告)日:2022-07-07
申请号:PCT/TR2021/051502
申请日:2021-12-24
摘要: The present invention is related to reduced graphene oxide (rGO) nanoplatforms coated with a methacrylate-based copolymer and the methods used in the preparation of these platforms for use as a drug carrier system.
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7.
公开(公告)号:WO2022132109A1
公开(公告)日:2022-06-23
申请号:PCT/TR2021/051424
申请日:2021-12-16
发明人: ARSLAN, Hüseyin , NADERI, Sanaz
IPC分类号: H04L27/26
摘要: A novel method for cyclic prefix (CP) adaptation based on wireless channel randomness is proposed for orthogonal frequency-division multiplexing (OFDM) systems. Specifically, a quantization algorithm and an adaptive window-based strong subcarriers selection are designed on the sorted channel frequency response of the legitimate party to randomly select the secure CP (SCP) length for each OFDM symbol without the need to share any information between legitimate nodes. The proposed technique creates a problem for illegitimate user's synchronization as it does not have any information about SCP length for every OFDM symbol, even if it uses blind synchronization techniques.
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公开(公告)号:WO2022132104A1
公开(公告)日:2022-06-23
申请号:PCT/TR2021/051414
申请日:2021-12-15
发明人: KAYA, Berkay , ATILGAN, Esra , ÖZDEMİR GÖRGÜ, Sena
IPC分类号: A61H23/02
摘要: The invention relates to a treatment vest that is compatible with the anatomical shape of the lungs and facilitates the excretion of secretions (sputum) accumulated in the lungs, consisting of the motor housing (1), motor cover (1a), hollow plastic ball (1b), rubber (2), vibration motor (3), battery housing (4), potentiometer (5), cotton outer lining of the vest (6), vest lock (7), vibration sensors (8), mobile device (9), motion sensor (10), pulse oximeter (11), connecting cable (12) and temperature sensor (13) parts.
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9.
公开(公告)号:WO2021015700A1
公开(公告)日:2021-01-28
申请号:PCT/TR2020/050633
申请日:2020-07-19
发明人: YOZGAT, Yasemin
IPC分类号: C12N15/00 , A61K31/7105 , A61K31/711
摘要: This invention relates to an isoform of hexokinase 1 (HK1), namely hexokinase 1b (HK1b), for use as a prognosis marker and as a specific target for use in treatment of cancer.
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公开(公告)号:WO2020149813A1
公开(公告)日:2020-07-23
申请号:PCT/TR2020/050034
申请日:2020-01-19
发明人: BAYRAKTAR, Zeki
摘要: The present invention is related to a method for increasing sperm motility. The present invention is characterized by increasing sperm motility without the need to apply a chemical or invasive method.
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