公开(公告)号：WO2020106197A1

公开(公告)日：2020-05-28

申请号：PCT/SE2019/051010

申请日：2019-10-14

Applicant: PRISMATIC SENSORS AB

Inventor： DANIELSSON, Mats ,  SUNDBERG, Christel

IPC: G01T1/24 ,  A61B6/03 ,  G01N23/04 ,  G01T1/29

Abstract: There is provided an x-ray imaging system (100) comprising an x-ray source (10), and an associated x-ray detector (20), wherein the x-ray detector (20) is a photon counting x-ray detector for enabling detection of photon-counting events. The x-ray imaging system (100) is configured for enabling acquisition of at least one phase contrast image based on detected photon-counting events. The x-ray detector (20) is based on a number of x-ray detector sub-modules, also referred to as wafers, each of which comprises detector elements, wherein the x-ray detector sub-modules are oriented in edge-on geometry with their edge directed towards the x-ray source, assuming the x- rays enter through the edge. Each x-ray detector sub-module or wafer has a thickness with two opposite sides of different potentials to enable charge drift towards the side, where the detector elements, also referred to as pixels, are arranged. The x-ray imaging system (100) is further configured to determine an estimate or measure of charge diffusion originating from a Compton interaction or an interaction through photoeffect related to an incident x-ray photon in an x-ray detector sub-module or wafer of the x-ray detector, and to determine an estimate of a point of interaction of the incident x-ray photon in the x-ray detector sub-module based on the determined estimate or measure of charge diffusion.

公开(公告)号：WO2020040681A1

公开(公告)日：2020-02-27

申请号：PCT/SE2019/050732

申请日：2019-08-09

Applicant: FOGELBERG CONSULTING AB

Inventor： FOGELBERG, Thomas

IPC: H01F27/245 ,  H01F27/26 ,  H01F41/02

Abstract: A method and an apparatus for almost scrap-less manufacturing of magnetic cores (100; 150; 200; 250) for electrical power transformers or reactors are provided. The method comprises the steps of cutting (S10) a cut-out (41) from the middle of a long side of a rectangular yoke plate made of electrical steel such that a symmetric gap is formed in the yoke plate, forming (S20) building elements (40; 40') of grain oriented electrical steel either from the cut-out (41) or from a rectangular limb plate, repositioning (S30) the building elements such that at least some of the building elements get a new orientation and/or position in relation to the yoke plate or the limb plate, and building (S50) a magnetic core (100; 150; 200; 250) by assembling at least yoke plates and repositioned building elements such that the repositioned building elements fit into the symmetric gaps formed in the yoke plates. Magnetic cores (100; 150; 200; 250) for electrical power transformers or reactors are also provided, where the core losses and noise levels are reduced compared to prior art technology. In particular, magnetic hybrid cores with grain oriented electrical steel and amorphous steel are provided.

公开(公告)号：WO2019209152A1

公开(公告)日：2019-10-31

申请号：PCT/SE2018/050764

申请日：2018-07-13

Applicant: BERGSTRÖM, Tomas ,  ANDERSSON, Göran ,  MÄKELÄINEN, Suvi ,  EKESTEN, Björn

Inventor： BERGSTRÖM, Tomas ,  ANDERSSON, Göran ,  MÄKELÄINEN, Suvi ,  EKESTEN, Björn

IPC: C12Q1/6883 ,  A01K67/02 ,  C12Q1/6827 ,  G01N33/48 ,  G01N33/68

Abstract: The invention relates to the detection of a 1 bp insertion in or near a cytosine mononucleotide repeat region in a canine ABCA4 gene. The resulting frameshift mutation generates a premature stop codon and a truncated ABCA4 protein. Dogs homozygous for the mutation suffer from an autosomal recessive retinal degenerative disease with a phenotype similar to Stargardt disease in humans. The invention also covers diagnosing a canine subject with an autosomal recessive retinal degenerative disease, by detecting the presence of the specific mutation. In addition, the invention covers the use of a canine subject homozygous for the ABCA4 mutation as a canine model for human autosomal recessive retinal degenerative disease, as well as the generation of such model animals via breeding of homozygous or heterozygous canine subjects.

公开(公告)号：WO2019161904A1

公开(公告)日：2019-08-29

申请号：PCT/EP2018/054483

申请日：2018-02-23

Applicant: KAMEL, Wael Sayed Saleh Elsayed ,  AKUSJÄRVI, Göran

Inventor： KAMEL, Wael Sayed Saleh Elsayed ,  AKUSJÄRVI, Göran

IPC: C12N15/11

Abstract: An RNA molecule (1) comprises a RNA fragment (2) and a hairpin RNA fragment (3). The hairpin RNA fragment (3) comprises a first stem region (10) comprising the RNA sequence GCGUCG, a loop region (20) comprising the RNA sequence CUGUCCA and a second stem region (30) comprising the RNA sequence CGAGCGC. The RNA fragment (2) constitutes a functional domain of the RNA molecule (1), whereas the hairpin RNA fragment (3) constitutes a stabilizing domain inhibiting degradation of the RNA fragment (2).

公开(公告)号：WO2019160491A1

公开(公告)日：2019-08-22

申请号：PCT/SE2019/050134

申请日：2019-02-15

Applicant: ASTREGO DIAGNOSTICS AB

Inventor： BALTEKIN, Özden ,  ÖHMAN, Ove ,  LOVMAR, Martin ,  ELF, Johan ,  OLSSON, Mikael

IPC: G01N33/487 ,  B01D61/14 ,  B81B1/00 ,  G01N33/483

Abstract: A microfluidic device (1) comprises a substrate (10) having a flow input channel (30) in fluid connection with a first fluid port (31) and a flow output channel (40) in fluid connection with a third fluid port (41) and cell channels (20) disposed between the flow input channel (30) and the flow output channel (40). The cell channels (20) comprise a respective obstruction (25) designed to prevent the target cells from passing the respective obstruction (25) and into the flow output channel (40). The microfluidic device (1) also comprises a pre-filter (50) with a filter channel (60) in fluid connection with a first filter port (61) and pre-filter channels (70) adapted to accommodate the target cells. A respective first end (72) of the pre- filter channels (70) is in fluid connection with the filter channel (60) and a respective second end (74) of the pre-filter channels (70) is in fluid connection with the flow input channel (30).

公开(公告)号：WO2019108113A8

公开(公告)日：2019-06-06

申请号：PCT/SE2018/051203

申请日：2018-11-20

Applicant: VALMET AB

Inventor： LINDBLOM, Thommy

IPC: B02C7/12 ,  D21B1/14 ,  D21D1/30

Abstract: Disclosed is a refiner plate (1) that is adapted to be attached to a rotatable refiner disc (10) on a refiner (100) for mechanical treatment of lignocellulosic material. The refiner plate (1) comprises a refining surface (11) that is adapted to be arranged oppositely a second refining surface (21) of a second refiner disc (20) on said refiner (100). The refining surface (11) is provided with a plurality of refining bars (110), where at least one of the refining bars (110) is provided with cavities (111) that are at least partially embedded in the refining bars. Moreover, at least one cavity (111) provided on the at least one refining bar (110) have one end (111a) arranged closer to the leading edge (112) of a refining bar (110) and one end (111 b) arranged closer to the trailing edge (113) of the refining bar and wherein the depth dimension of the cavity at the end (111a) is smaller than the depth dimension of the cavity at the end (111b).

公开(公告)号：WO2019108113A1

公开(公告)日：2019-06-06

申请号：PCT/SE2018/051203

申请日：2018-11-20

Applicant: VALMET AB

Inventor： LINDBLOM, Thommy

IPC: B02C7/12 ,  D21B1/14 ,  D21D1/30

Abstract: Disclosed is a refiner plate (1) that is adapted to be attached to a rotatable refiner disc (10) on a refiner (100) for mechanical treatment of lignocellulosic material. The refiner plate (1) comprises a refining surface (11) that is adapted to be arranged oppositely a second refining surface (21) of a second refiner disc (20) on said refiner (100). The refining surface (11) is provided with a plurality of refining bars (110), where at least one of the refining bars (110) is provided with cavities (111) that are at least partially embedded in the refining bars. Moreover, at least one cavity (111) provided on the at least one refining bar (110) have one end (111a) arranged closer to the leading edge (112) of a refining bar (110) and one end (111 b) arranged closer to the trailing edge (113) of the refining bar and wherein the depth dimension of the cavity at the end (111a) is smaller than the depth dimension of the cavity at the end (111b).

公开(公告)号：WO2019088904A1

公开(公告)日：2019-05-09

申请号：PCT/SE2018/051108

申请日：2018-10-30

Applicant: ASTREGO DIAGNOSTICS AB

Inventor： ELF, Johan ,  ÖHMAN, Ove ,  LOVMAR, Martin ,  BALTEKIN, Özden

IPC: B81B1/00 ,  C12Q1/06 ,  G01N33/487

Abstract: A microfluidic device (1) comprises a substrate (10) having spatially defined and separated cell compartments (20) configured to accommodate cells. A respective first end (22) of the spatially defined and separated cell compartments (20) is in fluid connection with a flow input channel (30). The microfluidic device (1) comprises at least one identification surface (60, 61) comprising immobilized affinity molecules configured to capture cells of a species or serotype or of a group of species or serotypes.

公开(公告)号：WO2018208197A1

公开(公告)日：2018-11-15

申请号：PCT/SE2017/050488

申请日：2017-05-12

Applicant: TELEFONAKTIEBOLAGET LM ERICSSON (PUBL)

Inventor： ANDERSSON, Stefan

IPC: H04J3/06

Abstract: A method for assisting in synchronization of slave clocks in a communication network comprises receiving, in a node (14; 16; 18) of the communication network, a message comprising a representation of a value of a synchronization accuracy (δ rec ) of a first upstream node (12; 14; 16) in the communication network. A value of an accuracy (δ link ) of a link latency unbalance between forward and reverse signalling in a link (21; 22; 23) on which the node ( 14; 16; 18) received the message is obtained. A value of a total synchronization accuracy (δ tot ) of the node ( 14; 16; 18) comprises at least the accuracy (δ link ) of said link latency unbalance of the link (21; 22; 23) on which the node (14; 16; 18) received the message is calculated. A node (14; 16; 18) for assisting in synchronization of slave clocks in a communication network is also presented.

公开(公告)号：WO2018160122A1

公开(公告)日：2018-09-07

申请号：PCT/SE2018/050184

申请日：2018-02-27

Applicant: MAGSTRÖM AB

Inventor： LUNDIN, Urban ,  ABRAHAMSSON, Johan ,  PEREZ-LOYA, J Jose

IPC: H02P1/46 ,  H02K19/12 ,  H02P3/18

CPC classification number: H02K1/146 ,  H02K3/487 ,  H02P1/46 ,  H02P6/32 ,  H02P2207/05

Abstract: An electrical synchronous machine (1) comprises a rotor (20) with rotor field windings (22) and a stator (10) with stator windings as well as a rotor power supply (50) and a stator power supply (60). The rotor power supply (50) is arranged to supply rotor field current for causing a magnetization of rotor magnetic poles (24). The stator power supply is arranged to supply alternating stator current for causing a rotating stator magnetic field. The electrical synchronous machine (1) further comprises at least one sensor (30), arranged to measure a quantity that is dependent on a relative angle between the rotor (20) and the rotating stator magnetic field. The electrical synchronous machine further comprises a rotor magnetization control arrangement (40), arranged for repeatedly varying amplitude and/or direction of the rotor current as a response to a change of the measured quantity. A corresponding control method is also disclosed.