公开(公告)号：WO2023080797A1

公开(公告)日：2023-05-11

申请号：PCT/NZ2022/050136

申请日：2022-11-04

Applicant: KORU DIAGNOSTICS LIMITED ,  PERNTHANER, Anton ,  HURST, Suzanne ,  FLOSSDORF, David

Inventor： PERNTHANER, Anton ,  HURST, Suzanne ,  FLOSSDORF, David

IPC: C12Q1/04 ,  C12Q1/28 ,  G01N21/25 ,  G01N33/569 ,  G01N33/53 ,  G01N33/543

Abstract: The invention relates to methods of screening biological samples from a subject for the presence of one or more microorganisms, such as the presence in the subject of one or more pathogenic or potentially pathogenic microorganisms, and diagnostic kits and devices suitable for carrying out said methods. More particularly, the present invention relates to sensitive and specific methods for determining the presence of gram-negative bacteria or analytes therefrom in a sample from a subject using immunoassays, and devices and kits for carrying out such methods.

公开(公告)号：WO2023027601A1

公开(公告)日：2023-03-02

申请号：PCT/NZ2022/050114

申请日：2022-08-26

Applicant: FISHER & PAYKEL HEALTHCARE LIMITED

Inventor： VAN SCHALKWYK, Andre ,  O'DONNELL, Kevin Peter

IPC: A61M16/04 ,  A61M16/08

Abstract: A tracheostomy guard (10, 30, 40, 50) for a patient interface is provided. The tracheostomy guard (10, 30, 40, 50) comprises a first portion (11) arranged to connect to a patient interface, in use, a second portion (12) attached to the first portion and configured to be in fluid communication with the patient interface and/or the first portion (11), in use. The second portion (12) comprising at least one first member (121) and/or second member (122) forming at least one aperture in fluid communication with the ambient environment, wherein the aperture (13) has a size that is variable in response to a force applied to at least part of the second portion, in use. An assembly (100) comprising the tracheostomy guard, a valve unit, a valve component, and a kit of parts, are also provided.

公开(公告)号：WO2023282771A1

公开(公告)日：2023-01-12

申请号：PCT/NZ2022/050092

申请日：2022-07-08

Applicant: COVID-19 VACCINE CORPORATION LIMITED

Inventor： FELDMAN, Robert Graham ,  HERBERT, Andrew Brian ,  HOLLINGS, Andrew James ,  MAZZOCCO, Giovanni ,  MYRONOV, Alexander ,  NIEMIEC, Iga ,  STĘPNIAK, Piotr ,  KOLBACHER, Oliver ,  SCHUBERT, Benjamin

IPC: C07K14/005 ,  C07K14/165 ,  A61P31/14 ,  A61K39/00 ,  A61K39/215 ,  C12N7/00

Abstract: The present disclosure relates to a multivalent vaccine composition characterised in that it elicits broad spectrum protection against at least one strain of coronavirus (such as a viral lineage, in particular SARS-Cov-2, more specifically selected from B.1.617. 2 [delta and/or kappa variants], B.1.1.7 and/or omicron), said vaccine comprising: a pool of T cell epitopes derived from at least one viral protein wherein the vaccine has a calculated world population HLA coverage of at least 95%, for example 95.5%, 96%, 96.5%, 97%, 97.5%, 98%, 98.5%, 99%, 99.1%, 99.2%, 99.3%, 99.4%, 99.5%, 99.6%, 99.7%, 99.8%. The disclosure also relates to constructs disclosed herein, methods or preparing same and use in treatment including prophylaxis.

公开(公告)号：WO2022260537A1

公开(公告)日：2022-12-15

申请号：PCT/NZ2022/050068

申请日：2022-06-07

Applicant: KAY, David Godfrey

Inventor： KAY, David Godfrey

IPC: F04F5/52 ,  F04F5/04 ,  F04F5/42

Abstract: An apparatus for generating a negative pressure has an upper flow director, an inlet for directing a driving liquid into the upper flow director, a lower flow director in fluid communication with the upper flow director, and a vacuum port. The upper flow director is shaped to induce a first spiralling flow in which the driving liquid flows in a generally inwardly and downwardly spiralling manner about a first spiral axis. The lower flow director is shaped to induce a second spiralling flow in a generally inwardly and upwardly spiralling manner about a second spiral axis. Flow of the driving liquid through the apparatus generates a negative pressure at the vacuum port.

公开(公告)号：WO2022182253A1

公开(公告)日：2022-09-01

申请号：PCT/NZ2022/050020

申请日：2022-02-24

Applicant: IQ SCIENCE LIMITED ,  SILVA, Saimon Moraes

Inventor： KUMAR, Shalen ,  BRITO, Angel ,  TROBIANI, Laura

IPC: C12N15/115 ,  C07H21/00 ,  C12Q1/70 ,  G01N33/569

Abstract: The present invention is concerned with the detection of a SARS-Cov-2 virus antigen including, for example, a SARS-Cov-2 virus nucleocapsid protein and/or a SARS-Cov-2 virus spike protein. The present invention provides novel polynucleotide sequences which spontaneously fold to form aptamers having secondary structure features that promote selective binding to a SARS-CoV-2 virus antigen. The present invention further provides test kits and assay methods which employ the polynucleotides described herein, to achieve a more accurate, lower cost, rapid diagnosis COVID-19 test intended to accelerate contact tracing and testing of individuals and the community in the management of the ongoing global pandemic caused by various strains of SARS-CoV-2 virus.

公开(公告)号：WO2022114965A1

公开(公告)日：2022-06-02

申请号：PCT/NZ2021/050205

申请日：2021-11-24

Applicant: AROA BIOSURGERY LIMITED

Inventor： WARD, Brian Roderick ,  MASON, Isaac Tristram Tane ,  ASEFI, Dorrin ,  ROSE, Hamish Joshua ,  GORMAN, Sean James ,  CHITTOCK, Henry David

IPC: A61M1/00 ,  A61F13/00 ,  A61M39/24

Abstract: A system for treating a wound, having a wound treatment device, a fluid input upstream side of the device, a fluid output downstream of the device; an air inlet valve upstream of the fluid output; an actuator to drive the air inlet valve between open and closed positions; a pump downstream of the fluid input; a motor to drive the pump to provide a negative pressure to the device; and a controller in configured to operate the air inlet valve and the pump. The controller is configured to (i) open the air inlet valve and operate the pump to maintain a first vacuum pressure at the wound treatment device and introduce air into the device, and (ii) close the air inlet valve and operate the pump to maintain a second vacuum pressure at the wound treatment device and remove air and fluid from the device.

公开(公告)号：WO2022103283A1

公开(公告)日：2022-05-19

申请号：PCT/NZ2021/050202

申请日：2021-11-12

Applicant: INSITUGEN LIMITED

Inventor： HEATHER, Alison Kay

IPC: C12Q1/6897 ,  G01N33/74 ,  C12N9/22

Abstract: The present invention provides diagnostic test kits and assay methods involving the detection of steroid hormone ligand(s) in a test sample. For example, in the detection of ligands which bind to and activate an androgen receptor, estrogen receptor, progesterone receptor, mineralocorticoid receptor and glucocorticoid receptor. In particular, the test kits and assay methods described herein are configured for field-based applications, for example, for trackside drug testing in athletes or at home testing of humans or animals for steroid hormone activity, which test kits, assays and methods colorimetric read-outs involving either inorganic pyrophosphate or CRISPR/Cas mediated RNA probe cleavage involving (e.g.) probes which have a detectable label including fluorophore/quencher molecules or fluorophore/tag molecules. Accordingly, the diagnostic test kits and assay methods described herein eliminate the requirement for detection instrumentation allowing reproducible 'rapid fire' tests in the field.

公开(公告)号：WO2022039604A1

公开(公告)日：2022-02-24

申请号：PCT/NZ2021/050139

申请日：2021-08-20

Applicant: PICTOR LIMITED

Inventor： VASHIST, Sandeep Kumar ,  TEJERINA, Jimena Maria

IPC: C07K14/47 ,  C07K16/18 ,  C07K16/40 ,  G01N33/04 ,  G01N33/53 ,  G01N33/535 ,  G01N33/543 ,  G01N33/58 ,  G01N33/68

Abstract: Johne's disease, an infection caused by Mycobacterium avium paratuberculosis (MAP), is a major production limiting disease of dairy cows. Calves can become infected with Johne's disease during birth. The present invention provides methods for detecting both Johne's disease and pregnancy associated glycoproteins in a single multiplex immunoassay.

公开(公告)号：WO2020130857A1

公开(公告)日：2020-06-25

申请号：PCT/NZ2019/050164

申请日：2019-12-20

Applicant: VICTORIA LINK LIMITED

Inventor： BORAH, Rohan ,  NANN, Thomas ,  HUGHSON, Fraser Ross

IPC: H01G11/60 ,  H01M10/26

Abstract: Disclosed are electrolyte compositions for electrochemical devices, where the electrolyte compositions comprise a microemulsion and where the microemulsion comprises an aqueous phase and a water-immiscible phase. Also disclosed are microemulsion electrolyte compositions for electrically rechargeable electrochemical energy storage devices, including ion batteries (such as lithium ion, sodium ion, magnesium ion, calcium ion, and aluminium ion batteries), redox flow batteries and supercapacitors.

公开(公告)号：WO2020130854A1

公开(公告)日：2020-06-25

申请号：PCT/NZ2019/050161

申请日：2019-12-20

Applicant: ECOLIBRIUM BIOLOGICALS HOLDINGS LIMITED ,  FORD, Stephen Reynold ,  TREADWELL, Michael ,  SIGDEL, Ankita ,  KIMBLE, Bernard

Inventor： FORD, Stephen Reynold ,  TREADWELL, Michael ,  SIGDEL, Ankita ,  KIMBLE, Bernard

IPC: A01N25/04 ,  A01N63/30 ,  A01N57/20

Abstract: The invention relates to compositions for use in agriculture and horticulture, wherein the compositions comprise one or more carbohydrates and one or more active agents selected from the group comprising one or more phytotoxins, one or more nutrients, and one or more organic molecules. Methods of preparing and using the compositions are also provided, for example in the control of unwanted plants, to promote the growth of one or more desired plants, and/or to minimise environmental impacts stemming from the widespread use of large quantities and concentrations of agricultural chemicals.