NON-INVASIVE IMAGING OF TISSUE REDOX STATE BY MRI
    1.
    发明申请
    NON-INVASIVE IMAGING OF TISSUE REDOX STATE BY MRI 审中-公开
    通过磁共振成像技术对组织红霉素进行非侵入成像

    公开(公告)号:WO2014165719A1

    公开(公告)日:2014-10-09

    申请号:PCT/US2014/032901

    申请日:2014-04-04

    Abstract: Chemical exchange saturation transfer technique is tailored to obtain chemical exchange saturation transfer contrast and redox status of tumors. Tissue is imaged in such a way to characterize its heterogeneity and correlate with the redox state of the tumor with sensitivity to the corona and core structure of the tumor. The method includes creating a detectable chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) contrast with frequency selective saturation of exchangeable protons associated with a redox reaction of a tissue, identifying metabolites in the tissue that express CEST MRI contrast in vivo, and quantifying a redox state of the tissue based on the MRI contrast.

    Abstract translation: 化学交换饱和转移技术被定制以获得肿瘤的化学交换饱和转移对比和氧化还原状态。 组织以这样的方式成像,以表征其异质性并与肿瘤的氧化还原状态相关,对肿瘤的电晕和核心结构具有敏感性。 该方法包括创建可检测的化学交换饱和转移(CEST)磁共振成像(MRI)对比度,其与组织的氧化还原反应相关的可交换质子的频率选择饱和,识别组织中表达体内CEST MRI对比的代谢物,以及 基于MRI对比度量化组织的氧化还原状态。

    ENABLING AWARENESS AND COORDINATION AMONG APPLICATIONS

    公开(公告)号:WO2023077154A1

    公开(公告)日:2023-05-04

    申请号:PCT/US2022/079049

    申请日:2022-11-01

    Abstract: An application coordination service (ACS) enables awareness among applications and perform coordination actions regarding these applications. For example, application client may request application coordination service from an ACS client. The ACS client may identify the influencer applications that are of interest, monitor the activities and status of the influencer applications, generate notifications, or determine and perform actions regarding the service request.

    ARCHITECTURE ENHANCEMENTS FOR NETWORK SLICING

    公开(公告)号:WO2023049744A1

    公开(公告)日:2023-03-30

    申请号:PCT/US2022/076776

    申请日:2022-09-21

    Abstract: A user equipment (UE) may detect that two or more of the slices that were requested by the UE cannot be served by the same access and mobility management function (AMF). Once the UE is able to determine that the multiple requested slices cannot be served by the same AMF, the UE may account for this incompatibility. For example, the UE may decide to only request compatible slices, or the UE may execute procedures with the network that allow the UE to simultaneously communicate with multiple AMFs. By allowing the UE to communicate with multiple AMFs, the UE may be able to utilize separate AMFs to register to slices that cannot be served by the same AMF. The system may allow for the UE to be paged by multiple AMFs.

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